Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Makoto HORIUCHI"'
Autor:
Wataru Hirose, Makoto Horiuchi, Donghan Li, Ikuko N. Motoike, Lin Zhang, Hafumi Nishi, Yusuke Taniyama, Takashi Kamei, Mikiko Suzuki, Kengo Kinoshita, Fumiki Katsuoka, Keiko Taguchi, Masayuki Yamamoto
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 1, Pp 153-178 (2023)
Background & Aims: NF-E2-related factor 2 (NRF2) is a transcription factor that regulates cytoprotective gene expression in response to oxidative and electrophilic stresses. NRF2 activity is mainly controlled by Kelch-like ECH-associated protein 1 (K
Externí odkaz:
https://doaj.org/article/ff35abbc6e624ce2a687505c62afc73f
Autor:
Makoto Horiuchi, Christian J. Hinderer, Jenny A. Greig, Cecilia Dyer, Elizabeth L. Buza, Peter Bell, Jessica A. Chichester, Peter M. Hayashi, Hanying Yan, Tamara Goode, James M. Wilson
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 272-280 (2022)
Gene therapy using neurotropic adeno-associated virus vectors represents an emerging solution for genetic disorders affecting the central nervous system. The first approved central nervous system-targeting adeno-associated virus gene therapy, Zolgens
Externí odkaz:
https://doaj.org/article/47d10615a3624fa0872c118998bf302a
Autor:
Junichi Tsunokake, Yusuke Taniyama, Fumiyoshi Fujishima, Chiaki Sato, Hiroshi Okamoto, Toshiaki Fukutomi, Yohei Ozawa, Naoto Ujiie, Ken Koseki, Yusuke Gokon, Makoto Horiuchi, Ryujiro Akaishi, Takuro Yamauchi, Michiaki Unno, Takashi Kamei
Publikováno v:
Surgical Case Reports, Vol 7, Iss 1, Pp 1-7 (2021)
Abstract Background Esophageal achalasia causes dysphagia following impaired relaxation of the lower esophageal sphincter due to the degeneration of Auerbach’s plexus in the esophageal smooth muscle. Recently, peroral endoscopic myotomy (POEM) has
Externí odkaz:
https://doaj.org/article/090f8686bec443b7a5be7acb71de51ff
Autor:
Joshua J Sims, Jenny A Greig, Kristofer T Michalson, Sharon Lian, R Alexander Martino, Rosemary Meggersee, Kevin B Turner, Kalyani Nambiar, Cecilia Dyer, Christian Hinderer, Makoto Horiuchi, Hanying Yan, Xin Huang, Shu-Jen Chen, James M Wilson
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009544 (2021)
SARS-CoV-2 variants have emerged with enhanced pathogenicity and transmissibility, and escape from pre-existing immunity, suggesting first-generation vaccines and monoclonal antibodies may now be less effective. Here we present an approach for preven
Externí odkaz:
https://doaj.org/article/1456eae8f81744b0b130542e55e5bbc3
Publikováno v:
Nihon Kikai Gakkai ronbunshu, Vol 82, Iss 844, Pp 16-00300-16-00300 (2016)
The demands for reduction of noise, vibration and harshness in the vehicle are getting increased in these years. In order to achieve the demands, the most efficient way is to reduce the input to the vehicle body. There are many investigations of the
Externí odkaz:
https://doaj.org/article/a954ecef4c5540cfa433e88835ea0c60
Autor:
Makoto Horiuchi, Christian J. Hinderer, Hailey N. Shankle, Peter M. Hayashi, Jessica A. Chichester, Casey Kissel, Peter Bell, Cecilia Dyer, James M. Wilson
Publikováno v:
Human Gene Therapy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fe7b89f769159071052d5af773cb031
https://doi.org/10.1089/hum.2022.216
https://doi.org/10.1089/hum.2022.216
Autor:
Wataru Hirose, Makoto Horiuchi, Yusuke Taniyama, Takashi Kamei, Keiko Taguchi, Masayuki Yamamoto
Publikováno v:
Diseases of the Esophagus. 35
Nrf2 is a transcription factor that regulates cytoprotective genes in response to oxidative and electrophilic stresses. The activity of Nrf2 is mainly controlled by the protein degradation by Keap1, a ubiquitin E3 ligase adaptor. Most of esophageal s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c70e1cfcbed2a0d2a824c9538edd2cc1
https://doi.org/10.1093/dote/doac051.206
https://doi.org/10.1093/dote/doac051.206
Autor:
Yusuke Gokon, Junichi Tsunokake, Toshiaki Fukutomi, Takuro Yamauchi, Yusuke Taniyama, Hiroshi Okamoto, Fumiyoshi Fujishima, Ryujiro Akaishi, Makoto Horiuchi, Chiaki Sato, Yohei Ozawa, Ken Koseki, Takashi Kamei, Michiaki Unno, Naoto Ujiie
Publikováno v:
Surgical Case Reports, Vol 7, Iss 1, Pp 1-7 (2021)
Surgical Case Reports
Surgical Case Reports
Background Esophageal achalasia causes dysphagia following impaired relaxation of the lower esophageal sphincter due to the degeneration of Auerbach’s plexus in the esophageal smooth muscle. Recently, peroral endoscopic myotomy (POEM) has become on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::684e01a223c6dd74a7a67e5d95681d66
https://doaj.org/article/090f8686bec443b7a5be7acb71de51ff
https://doaj.org/article/090f8686bec443b7a5be7acb71de51ff
Autor:
Ayumi Kuga, Kouhei Tsuchida, Harit Panda, Makoto Horiuchi, Akihito Otsuki, Keiko Taguchi, Fumiki Katsuoka, Mikiko Suzuki, Masayuki Yamamoto
Publikováno v:
Mol Cell Biol
Nrf2 activates cytoprotective gene expression, and Nrf2 activity is regulated through at least two protein degradation pathways: the Keap1-mediated and β-TrCP-mediated pathways. To address the relative contributions of these pathways, we generated k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20afe1b5dbcd4ce6b76c72e426517d6
https://europepmc.org/articles/PMC9302178/
https://europepmc.org/articles/PMC9302178/
Autor:
Xinpei Jiang, George M. Smith, Shin-ichi Muramatsu, Armin Sami, Makoto Horiuchi, Lena Ma, Shuxin Li, Yosuke Ohtake, Kieran Slattery, Michael E. Selzer
Publikováno v:
Molecular Therapy. 27:102-117
Liver kinase B1 (LKB1), a downstream effector of cyclic AMP (cAMP)/PKA and phosphatidylinositol 3-kinase (PI3K) pathways, is a determinant for migration and differentiation of many cells, but its role in CNS axon regeneration is unknown. Therefore, L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5feb5a91dfc211b53c81e8009bc0cc0
https://doi.org/10.1016/j.ymthe.2018.10.019
https://doi.org/10.1016/j.ymthe.2018.10.019