Zobrazeno 1 - 10
of 233
pro vyhledávání: '"Makoto FUJIWARA"'
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
ObjectiveCheckpoint inhibitors (CPIs) can trigger complications related to the autoimmune process such as CPI-triggered diabetes mellitus. The typical treatment for CPI-triggered diabetes is insulin, but a detailed therapeutic method has not yet been
Externí odkaz:
https://doaj.org/article/7df53643dc4b475084a17fd68d037c20
Autor:
Hiroshi Ogata, Shigeki Kitamura, Makoto Fujiwara, Masaru Shimizu, Chengbo Tan, Songji Zhao, Yuko Maejima, Kenju Shimomura
Publikováno v:
Dose-Response, Vol 21 (2023)
Sulfamethoxazole (SMX) is widely used as an antibiotic in the clinical application with side effects of hypoglycemia. This is because SMX contains the sulfonamide structure, which closes ATP-sensitive potassium (K ATP ) channels and induces insulin s
Externí odkaz:
https://doaj.org/article/fe05354e2280460a8227d748e50d6cf3
Publikováno v:
Bone Reports, Vol 18, Iss , Pp 101673- (2023)
Pachydermoperiostosis (PDP) is a rare hereditary disease characterized by digital clubbing, pachydermia, and periostosis. We describe a Japanese male patient with PDP who was differentially diagnosed with acromegaly by identification of compound hete
Externí odkaz:
https://doaj.org/article/407b3d0dbaa64da39e9e5990edc8c84f
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-4 (2022)
Abstract Objectives Due to the increase of type 2 diabetes (T2D), the number of patients in treatment with multiple anti-diabetic agents is increased. According to the recent recommendation of treatment guidelines, sodium-glucose cotransporter 2 (SGL
Externí odkaz:
https://doaj.org/article/234d8ac6a58d434491dd260102086da1
Publikováno v:
IEEE Journal of the Electron Devices Society, Vol 10, Pp 737-743 (2022)
In today’s data-driven society, memory is an unavoidable component. IoT and 5G are accelerating data generation exponentially, and the demands of high-capacity memory are increasing. Flash memory is a crucial infrastructure component and inevitable
Externí odkaz:
https://doaj.org/article/978fa323260e40998e56c81cf9be3490
Autor:
Jialiang S. Wang, Tushar Kamath, Courtney M. Mazur, Fatemeh Mirzamohammadi, Daniel Rotter, Hironori Hojo, Christian D. Castro, Nicha Tokavanich, Rushi Patel, Nicolas Govea, Tetsuya Enishi, Yunshu Wu, Janaina da Silva Martins, Michael Bruce, Daniel J. Brooks, Mary L. Bouxsein, Danielle Tokarz, Charles P. Lin, Abdul Abdul, Evan Z. Macosko, Melissa Fiscaletti, Craig F. Munns, Pearl Ryder, Maria Kost-Alimova, Patrick Byrne, Beth Cimini, Makoto Fujiwara, Henry M. Kronenberg, Marc N. Wein
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
The molecular circuitry that drives dendrite formation during osteocytogenesis remains poorly understood. Here the authors show that deletion of Sp7, a gene linked to rare and common skeletal disease, in mature osteoblasts and osteocytes causes sever
Externí odkaz:
https://doaj.org/article/cd91057df8104b6bb42af0b42b4a9105
Autor:
Yasuhisa Ohata, Taichi Kitaoka, Takeshi Ishimi, Chieko Yamada, Yukako Nakano, Kenichi Yamamoto, Shinji Takeyari, Hirofumi Nakayama, Makoto Fujiwara, Takuo Kubota, Keiichi Ozono
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0290812 (2023)
Osteogenesis imperfecta (OI) is a hereditary skeletal disease characterized by bone fragility. Areal bone mineral density (BMD), evaluated by dual-energy X-ray absorptiometry (DXA), is used to assess bone brittleness. The height-adjusted BMD Z-score
Externí odkaz:
https://doaj.org/article/217a64d86a1240f3afcf2f178fd93abb
Autor:
Yasuhisa Ohata, Haruna Kakimoto, Yuko Seki, Yasuki Ishihara, Yukako Nakano, Kenichi Yamamoto, Shinji Takeyari, Makoto Fujiwara, Taichi Kitaoka, Satoshi Takakuwa, Takuo Kubota, Keiichi Ozono
Publikováno v:
Bone Reports, Vol 17, Iss , Pp 101637- (2022)
Pseudohypoparathyroidism 1A (PHP1A) and pseudopseudohypoparathyroidism (PPHP) are caused by loss-of-function variants of GNAS, which encodes Gsα. We present two unrelated Japanese families with PHP1A and PPHP harboring unreported pathogenic variants
Externí odkaz:
https://doaj.org/article/1bb2d9ce3da440dd8c935b6b42dd836e
Autor:
Kazunori Fukushima, Keiko Kawai-Kowase, Yukio Yonemoto, Makoto Fujiwara, Hiroko Sato, Mahito Sato, Takuo Kubota, Keiichi Ozono, Junich Tamura
Publikováno v:
Journal of Medical Case Reports, Vol 13, Iss 1, Pp 1-6 (2019)
Abstract Background Hypophosphatasia is an inherited bone disease characterized by low alkaline phosphatase activity encoded by ALPL. Clinically, hypophosphatasia can be categorized as perinatal, infantile, childhood, and adult forms, as well as odon
Externí odkaz:
https://doaj.org/article/0f6c85a1e6274fb886e71a94995499c4
Autor:
Kohji Miura, Noriyuki Namba, Makoto Fujiwara, Yasuhisa Ohata, Hidekazu Ishida, Taichi Kitaoka, Takuo Kubota, Haruhiko Hirai, Chikahisa Higuchi, Noriyuki Tsumaki, Hideki Yoshikawa, Norio Sakai, Toshimi Michigami, Keiichi Ozono
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42180 (2012)
We describe a three-generation family with tall stature, scoliosis and macrodactyly of the great toes and a heterozygous p.Val883Met mutation in Npr2, the gene that encodes the CNP receptor NPR2 (natriuretic peptide receptor 2). When expressed in HEK
Externí odkaz:
https://doaj.org/article/7666ccd6a6b84b47b4c07294efaeea88