Evaluation of the Safety and Gastrointestinal Migration of Guanidinylated Chitosan after Oral Administration to Rats

Autor: Nowshin Farzana Khan, Hideaki Nakamura, Hironori Izawa, Shinsuke Ifuku, Daisuke Kadowaki, Masaki Otagiri, Makoto Anraku

Publikováno v: Journal of Functional Biomaterials, Vol 14, Iss 7, p 340 (2023)

Arginine-rich membrane-permeable peptides (APPs) can be delivered to cells by forming complexes with various membrane-impermeable bioactive molecules such as proteins. We recently reported on the preparation of guanidinylated chitosan (GCS) that mimi

Externí odkaz: https://doaj.org/article/3727352d13c0488783caea833d2d9ac9

Metal-catalyzed oxidation of human serum albumin does not alter the interactive binding to the two principal drug binding sites

Autor: Keishi Yamasaki, Koji Nishi, Makoto Anraku, Kazuaki Taguchi, Toru Maruyama, Masaki Otagiri

Publikováno v: Biochemistry and Biophysics Reports, Vol 14, Iss C, Pp 155-160 (2018)

It is well known that various physiological factors such as pH, endogenous substances or post-translational modifications can affect the conformational state of human serum albumin (HSA). In a previous study, we reported that both pH- and long chain

Externí odkaz: https://doaj.org/article/74794110fec0470899bbbb0dd6cbf49b

Contributors

Autor: Rasaq Abolore, Makoto Anraku, Amit Arora, R. Baeza-Jiménez, Nagamani Balagurusamy, Shivali Banerjee, Prashant Bhagwat, Komal Bhise, Márquez-Cardozo Carlos Julio, Mary Carmen Martínez, Gaurav Chetal, Deki Choden, Kamlesh Chour, Anunava Das, Sukanya Das, Wangzin Dendup, Khomdram Bijoya Devi, Sashi Prava Devi, Neena K. Dhiman, Yepes-Betancur Diana, Cadena-Chamorro Edith, Juan Carlos Contreras Esquivel, R.M. Gade, Suresh Kumar Gadi, Ming Gao, Roeb García-Arrazola, Nalan Gokoglu, Prakash Halami, Qazi Parvaiz Hassan, Amit K. Jaiswal, Swarna Jaiswal, Dhruva Kumar Jha, Yan Jia, Yong Jin, Shrikalaa Kannan, Khushdil Khan, Meena Koche, Amrit Kumar, Franco Emanuel Lacava, Londoño-Hernandez Liliana, Hongzhi Ma, L.X. López-Martínez, Rahul Malakar, null Manju, Pedro Martínez Rodríguez, Navodita Maurice, María Rocío Meini, Natasha Melnichuk, Julio Montañez, Lourdes Morales-Oyervides, O. Márquez-Molina, Nargis Nazir, Roberto Olayo González, Roberto Olayo-Valles, Santhosh Pillai, Jintu Rabha, Vijaya Raghavan, Piyush Kant Rai, Shalini Rai, R.C. Ranveer, N.B. Rathod, E. Rojo-Gutiérrez, Diana Romanini, Niranjan Roy, H.K. Saenz-Hidalgo, Alka Sagar, Rashmi Saini, B.K. Sakhale, Aafreen Sakina, Nilam Sarma, Aditya Sharma, Sonia Sharma, Vishakha Sharma, Keiko Shirai, Sridevi Annapurna Singh, Jazel Doménica Sosa-Martínez, Phalisteen Sultan, Flor Tania Escárcega Olivares, A.R. Tapre, Bahiru Tsegaye, Salony Raghunath Vaishnav, Madan L. Verma, Miguel Ángel Villegas-Mendez, Humberto Vázquez, Qunhui Wang, Ashish Warghane, Chuanfu Wu, Saurabh Singh Yadav, Jian Yang, Ziqiang Yu, Cadavid-Mora Yuliana

Publikováno v: Value-Addition in Agri-food Industry Waste Through Enzyme Technology ISBN: 9780323899284

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d699aa9aeac95016b234bd77b4c0f4e9
https://doi.org/10.1016/b978-0-323-89928-4.00099-7

Design and Evaluation of An Extended-Release Olmesartan Tablet Using Chitosan/Cyclodextrin Composites

Autor: Makoto Anraku, Ryo Tabuchi, Miwa Goto, Daisuke Iohara, Yasuyuki Mizukai, Yuji Maezaki, Akihiro Michihara, Daisuke Kadowaki, Masaki Otagiri, Fumitoshi Hirayama

Publikováno v: Pharmaceutics, Vol 11, Iss 2, p 82 (2019)

Sustained-release olmesartan tablets (OLM) were prepared by the simple, direct compression of composites of anionic sulfobutyl ether-β-cyclodextrin (SBE-β-CD) and cationic spray-dried chitosan (SD-CS), and were evaluated for use as a sustained rele

Externí odkaz: https://doaj.org/article/6ff4d2a26ede46068896599db53afd60

The Effects of Sacran, a Sulfated Polysaccharide, on Gut Microbiota Using Chronic Kidney Disease Model Rats

Autor: Miwa Goto, Yusei Kobira, Shinichiro Kaneko, Hidetoshi Arima, Akihiro Michihara, Kazuo Azuma, Taishi Higashi, Keiichi Motoyama, Hiroshi Watanabe, Toru Maruyama, Daisuke Kadowaki, Masaki Otagiri, Daisuke Iohara, Fumitoshi Hirayama, Makoto Anraku

Publikováno v: Biologicalpharmaceutical bulletin. 45(5)

The aim of this study was to investigate the beneficial effects of sacran, a sulfated polysaccharide, on renal damage and intestinal microflora, in 5/6 nephrectomy rats as a model for chronic kidney disease (CKD). 5/6 Nephrectomy rats were divided in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4ff3304273c0143e7e53ac228f5b76
https://pubmed.ncbi.nlm.nih.gov/35491162