Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Makoto, Takehana"'
The Extracellular C-loop Domain Plays an Important Role in the Cell Adhesion Function of Aquaporin 0
Publikováno v:
Current Eye Research. 42:617-624
Although aquaporin 0 (AQP0) is a member of the AQP family, it has limited water permeability compared with other members. AQP0 may also have cell adhesion-related functions, but the evidence is still limited. Here, we studied the relationship of AQP0
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a67870acaf066c15f13a724c6a46af6f
https://doi.org/10.1080/02713683.2016.1217547
https://doi.org/10.1080/02713683.2016.1217547
Publikováno v:
Open Medicine, Vol 11, Iss 1, Pp 183-189 (2016)
Open Medicine
Open Medicine
Background. Chaperone activity of α-crystallin in the lens works to prevent protein aggregation and is important to maintain the lens transparency. This study evaluated the effect of hesperetin on lens chaperone activity in selenite-induced cataract
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312ed9b4c1029a03bbffd5a8ca5853d9
https://doaj.org/article/700c6d1a91914cb88faa7ced394381a9
https://doaj.org/article/700c6d1a91914cb88faa7ced394381a9
Publikováno v:
Biochemical and Biophysical Research Communications. 415:125-130
Aquaporin 0 (AQP0) is a lens-specific protein comprising more than 30% of lens membrane protein content and is a member of the aquaporin family. Water permeates through AQP0 much more slowly than other aquaporin family members, and other compounds, s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40fe206b41e27aa1af04db908d09123
https://doi.org/10.1016/j.bbrc.2011.10.028
https://doi.org/10.1016/j.bbrc.2011.10.028
Publikováno v:
Biomedicine & Preventive Nutrition. 1:43-48
Ascorbic acid (AA) is found in high concentrations in the lens and protects the lens from photochemical events such as photo-oxidation. Diabetes reduces the concentration of AA in the lens, and it has been suggested that AA supplementation may rescue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3045aca6e10eb348ddda7d5d32c8ad63
https://doi.org/10.1016/j.bionut.2010.09.008
https://doi.org/10.1016/j.bionut.2010.09.008
Publikováno v:
Journal of Health Science. 51:734-737
The Shumiya cataract rat (SCR) is a hereditary cataract model in which lens opacity appears spontaneously in both the nuclear and perinuclear regions of 10‐11 week old animals. The expression of drug metabolizing enzymes, including cytochrome P450
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::982454faeac27fe647766e4d7ab2c807
https://doi.org/10.1248/jhs.51.734
https://doi.org/10.1248/jhs.51.734
Autor:
Satoki Ueno, Mikako Oka, Shizuko Kobayashi, Makoto Takehana, Noriyasu Hada, Yumiko Aoyama, Jun Inoue, Tadahiro Takeda
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 20:1-13
We studied the intraocular pharmacokinetics of dorzolamide hydrochloride eye drops and the effect of dorzolamide on carbonic anhydrase activity and localization in ocular tissues. Carbonic anhydrase activity was detected in normal ocular tissues. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2cf64295adcdf089fa6f844cb4baf9
https://doi.org/10.1089/108076804772745419
https://doi.org/10.1089/108076804772745419
Autor:
Shizuko Kobayashi, Hajime Obazawa, Makoto Takehana, Kenji Kawai, Masayasu Bando, Ichiko Akatsuka, Mikako Oka, Takahiro Suzuki, Hideo Tsukamoto
Publikováno v:
Japanese Journal of Ophthalmology. 47:437-443
Purpose: To evaluate the relationship of λ-crystallin to reduced nicotinamide adenine dinucleotide (NADH)-dependent dehydroascorbate (DHA) reductase found specifically in the rabbit lens. Methods: DHA reductase Fractions I–IV were separated from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54a470acff97b16dc6d39d6e09649bb
https://doi.org/10.1016/s0021-5155(03)00140-0
https://doi.org/10.1016/s0021-5155(03)00140-0
Autor:
Shingo Tajima, Shizuko Kobayashi, Makoto Takehana, Noriko Yamaguchi, Yuko Matsubara, Akira Ishibashi, Atsushi Akagi
Publikováno v:
Journal of Investigative Dermatology. 118:267-274
We have previously reported that connective tissue cells in the superficial dermis preferentially express α 1 (XVI) collagen rather than those in the lower dermis. Double immunofluorescence labeling using the antibodies for α 1 (XVI) collagen and f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3333d5563c7c758892a4849bfb0df6f
https://doi.org/10.1046/j.0022-202x.2001.01666.x
https://doi.org/10.1046/j.0022-202x.2001.01666.x
Publikováno v:
Journal of Health Science. 48:346-349
Composition and inducibility of cytochrome P450 (CYP) in ocular tissues were investigated using reverse transcription-polymerase chain reaction (RT-PCR) and immunoblot techniques. Composition of ocular CYPs is more restricted than that of hepatic for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::417904bbce0fe9c457ce53978fcb2e78
https://doi.org/10.1248/jhs.48.346
https://doi.org/10.1248/jhs.48.346
Publikováno v:
Japanese Journal of Ophthalmology. 45:233-239
Purpose: To clarify the function of ascorbate free radical (AFR) reductase in the lens antioxidation mechanism, we investigated the difference among species in AFR reductase activity in different vertebrate lenses.Materials and Methods: Soluble and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5cef8d476d1084d600206840ef12cc
https://doi.org/10.1016/s0021-5155(00)00385-3
https://doi.org/10.1016/s0021-5155(00)00385-3