Zobrazeno 1 - 10
of 415
pro vyhledávání: '"Makoto, Otsuki"'
Publikováno v:
Gastroenterology Research and Practice, Vol 2010 (2010)
Animal models for CP in rats can be classified into 2 groups: one is noninvasive or nonsurgical models and the other is invasive or surgical models. Pancreatic injury induced by repetitive injections of supramaximal stimulatory dose of caerulein (Cn)
Externí odkaz:
https://doaj.org/article/9bec9aa0ea37423986c30596b03bc9b4
Autor:
Makoto Otsuki
Publikováno v:
Suizo. 32:110-124
Publikováno v:
Cell reports. 34(3)
Intercellular karyotype diversity, or aneuploidy, is a widespread feature of cancers propagated through continuous mitotic chromosome segregation errors, the condition called chromosomal instability. The protease separase is an essential enzyme that
Publikováno v:
International Journal Of Nutrition. 2:4-14
Publikováno v:
Metabolism. 65:41-53
Purpose The effects of statins on insulin resistance (IR) and type 2 diabetes mellitus (T2DM) are still controversial and its effects on pancreatic fibrosis are poorly defined. The purpose of this study is to examine the effects of atorvastatin on th
Autor:
Makoto Otsuki
Publikováno v:
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]. 17(4)
The Palade Prize is the most distinguished award of the IAP for achievement in pancreatic research. It is named after George E. Palade, who in 1974 was awarded the Nobel Prize for his work on protein trafficking in pancreatic acinar cells. It is a gr
Publikováno v:
Regulatory Peptides. 178:80-85
Background/aim The renin–angiotensin system (RAS) exists in the pancreas, but the role of RAS in the regulation of pancreatic exocrine secretion under physiological conditions has been little known. The present study addressed the RAS's effect on t
Publikováno v:
Laboratory Investigation. 91:872-884
As appropriate therapies for pancreatic fibrosis and inflammation are limited, prognosis of chronic pancreatitis has not improved to date. Recent studies have shown that statins improve inflammation and fibrosis in several organs. We therefore examin
Autor:
Tetsuhide Ito, Tooru Shimosegawa, Takamasa Oono, Yusuke Niina, Ryoichi Takayanagi, Masahiko Uchida, Hisato Igarashi, Makoto Otsuki, Isao Nishimori, Taichi Nakamura, Ken Kawabe, Nao Fujimori
Publikováno v:
Journal of Digestive Diseases. 12:210-216
OBJECTIVE: Although patients with autoimmune pancreatitis (AIP) tend to have concurrent diverse disorders, very few studies have focused on diabetes mellitus (DM) coexisting with AIP. METHODS: In total 102 AIP patients with DM were divided into three
Publikováno v:
Digestive Diseases and Sciences. 56:2326-2332
Little is known about the etiopathogenesis of chronic pancreatitis, due mainly to the lack of simple animal models suitable to study inflammatory and fibrogenetic processes in the pancreas. The purpose of this study was to examine whether transient c