Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Makoto, Mitsuhashi"'
Autor:
Takeshi Fukuda, Yuji Nagamine, Makoto Mitsuhashi, Jun Udaka, Tadashi Tokashiki, Hirofumi Osumi, Hiroya Ojiri, Tetsuro Nishizawa, Mitsuhito Yukawa, Keishi Marumo, Tomohiro Kayama, Kunihiko Fukuda, Yuya Okutsu, Kazuhiro Maeda, Hiroyuki Chino, Naoya Inagaki
Publikováno v:
Modern Rheumatology Case Reports. 3:165-171
We report a rare case of carpal tunnel syndrome with flexion contracture of the fingers caused by giant gouty tophi requiring surgery. A 57-year-old man presented with a 2-year history of numbness ...
Autor:
Kenichiro Doi, Hideki Wanibuchi, Shoji Fukushima, Jun Shen, Makoto Mitsuhashi, Elsayed I. Salim, Shinzoh Kudoh, Kazuto Hirata, Min Wei
Publikováno v:
Cancer Letters. 206:15-26
The DMBDD rat multi-organ carcinogenesis model based on two-stage carcinogenesis theory was revised to make more suitable assay system for detecting chemopreventive effects of chemical substances by increasing the doses of two carcinogens, 1,2-dimeth
Autor:
Hideki Wanibuchi, Tatsuya Nakatani, Keiichirou Morimura, Makoto Mitsuhashi, Atsuhiko Kiyota, Seiji Wada, Shoji Fukushima
Publikováno v:
Journal of Toxicologic Pathology. 17:219-222
In the present study, a suitable rat model for testing the modifying effect of liver injury on the rat male organ toxicity of endocrine disrupters was researched using thioacetamide (TAA) and carbon tetrachloride (CCl4) as liver toxicants. Male 8-wee
Autor:
Keiichirou Morimura, Seiji Wada, Makoto Mitsuhashi, Shoji Fukushima, Shuji Hayashi, Atsuhiko Kiyota, Tatsuya Nakatani, Hideki Wanibuchi
Publikováno v:
Journal of Toxicologic Pathology. 17:177-185
The modifying effects of liver injury on male reproductive organ toxicity of di-n-butyl phthalate (DBP) were studied using male F344 rats. Seventy-two male animals, aged 10 weeks at the commencement, were divided into 8 groups of 9 rats each. Groups
Autor:
Makoto Mitsuhashi, Elsayed I. Salim, Min Wei, Keiichirou Morimura, Shoji Fukushima, Jun Shen, Hideki Wanibuchi, Masaharu Moku, Kenichiro Doi
Publikováno v:
Cancer Letters. 202:11-16
Selective COX-2 inhibitors have been suggested to be an effective strategy in the prevention of colon cancer without the adverse side effects of non-selective, nonsteroid anti-inflammatory drugs. The present experiment was designed to assess the pote
Autor:
Tatsuya Nakatani, Hideki Wanibuchi, Seiji Wada, Kenichiro Doi, Chikayoshi Masuda, Keiichirou Morimura, Min Wei, Shoji Fukushima, Tadao Kakizoe, Makoto Mitsuhashi
Publikováno v:
Journal of Toxicologic Pathology. 16:19-23
The immunostimulatory α-galactosylceramide, KRN 7000 or (2S, 3S, 4R)-1-0-(α-D-galactopyranosyl)-2-(N-hexacosnoylamino)-1,3,4-octadecatrienol, might be anticipated to have antitumor activity in vivo apart from any direct toxicity to cancer cells. We
Autor:
Rikio Yoshimura, Yoshihiro Segawa, Hajime Sano, Tatsuya Nakatani, Yutaka Kawahito, Seiji Wada, Taro Hase, Makoto Mitsuhashi
Publikováno v:
Urology. 60:542-547
Objectives. To investigate the expression of peroxisome proliferator activator-receptor (PPAR)-alpha, beta, and gamma in human testicular cancer (TC) and normal testicular (NT) tissues, as well as the effects of the PPAR-gamma ligand. Recent studies
Publikováno v:
Journal of Urology. 165:1468-1472
Purpose: Cyclooxygenase-2 is considered to have an important role in the development of metastasis in cancer due to angiogenesis function. The expression of cyclooxygenase-2 was found to be up-regulated in colorectal carcinoma and other cancers. We i
Autor:
Masahide, Matsuyama, Rikio, Yoshimura, Makoto, Mitsuhashi, Kenji, Tsuchida, Yoshiaki, Takemoto, Yutaka, Kawahito, Hajime, Sano, Tatsuya, Nakatani
Publikováno v:
Oncology reports. 14(1)
The metabolism of arachidonic acid by either the cyclooxygenase or lipoxygenase (LOX) pathway is believed to play an important role in tumor promotion. We investigated the expression of 5- and 12-LOX in renal cell carcinoma (RCC), as well as the effe
Autor:
Seiji, Wada, Satoshi, Ito, Shinji, Yamamoto, Mitsuru, Yoshimoto, Keisuke, Inoue, Rikio, Yoshimura, Makoto, Mitsuhashi, Tatsuya, Nakatani
Publikováno v:
Hinyokika kiyo. Acta urologica Japonica. 50(9)
We report a case of stage I malignant melanoma of the penis (confined to the penis). A 74-year-old uncircumcised man noticed a nonhealing, painless black lesion in penile foreskin and visited our institute. As the lesion was confined to the prepuce,