Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Makoto, Kurano"'
Autor:
Baasanjav Uranbileg, Eri Sakai, Masayuki Kubota, Hideaki Isago, Masahiko Sumitani, Yutaka Yatomi, Makoto Kurano
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Mass spectrometry-based lipidomics approaches offer valuable tools for the detection and quantification of various lipid species, including sphingolipids. The present study aimed to develop a new method to simultaneously detect various sphin
Externí odkaz:
https://doaj.org/article/b216bbc5511c4397b54fee729e722fc8
Autor:
Christopher D. Green, Ryan D.R. Brown, Baasanjav Uranbileg, Cynthia Weigel, Sumit Saha, Makoto Kurano, Yutaka Yatomi, Sarah Spiegel
Publikováno v:
Molecular Metabolism, Vol 86, Iss , Pp 101971- (2024)
Objective: Hepatocellular carcinoma (HCC) is the third leading cause of cancer mortality, and its incidence is increasing due to endemic obesity. HCC is sexually dimorphic in both humans and rodents with higher incidence in males, although the mechan
Externí odkaz:
https://doaj.org/article/0d27976db3474a0b8686c16ec6a18ec0
Autor:
Takashi Suzuki, Makoto Kurano, Akari Isono, Takuya Uchino, Yohei Sayama, Honami Tomomitsu, Daiki Mayumi, Ruriko Shibayama, Toru Sekiguchi, Naoki Edo, Kiyoko Uno-Eder, Kenji Uno, Koji Morita, Toshio Ishikawa, Kazuhisa Tsukamoto
Publikováno v:
Endocrine Journal, Vol 71, Iss 5, Pp 447-460 (2024)
Severe hypertriglyceridemia is a pathological condition caused by genetic factors alone or in combination with environmental factors, sometimes leading to acute pancreatitis (AP). In this study, exome sequencing and biochemical analyses were performe
Externí odkaz:
https://doaj.org/article/df737d40b63b464983bd43999385bea5
Publikováno v:
Frontiers in Aging Neuroscience, Vol 16 (2024)
IntroductionAlzheimer’s disease (AD) is associated with disturbed metabolism, prompting investigations into specific metabolic pathways that may contribute to its pathogenesis and pathology. Sphingolipids have garnered attention due to their known
Externí odkaz:
https://doaj.org/article/db3b26a9d92044b88c9abaca2ce817d6
Publikováno v:
Frontiers in Nephrology, Vol 4 (2024)
BackgroundTo avoid an invasive renal biopsy, noninvasive laboratory testing for the differential diagnosis of kidney diseases is a desirable goal. As sphingolipids are demonstrated to be involved in the pathogenesis of various kidney diseases, we inv
Externí odkaz:
https://doaj.org/article/2add16f4c97f4a6caf8527f0d2fa0217
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115400- (2023)
The pleiotropic effects of high-density lipoprotein (HDL), including its protective properties against sepsis, are attributed to the sphingosine 1-phosphate and apolipoprotein M (ApoM) that are carried on the lipoproteins. In this study, we attempted
Externí odkaz:
https://doaj.org/article/8bb2bcfd61a043c5b2d00b6cd27686a4
Autor:
Takuya Shimura, Makoto Kurano, Koh Okamoto, Daisuke Jubishi, Hideki Hashimoto, Kuniyuki Kano, Koji Igarashi, Satoshi Shimamoto, Junken Aoki, Kyoji Moriya, Yutaka Yatomi
Publikováno v:
Annals of Medicine, Vol 54, Iss 1, Pp 3189-3200 (2022)
Introduction In order to identify therapeutic targets in Coronavirus disease 2019 (COVID-19), it is important to identify molecules involved in the biological responses that are modulated in COVID-19. Lysophosphatidic acids (LPAs) are involved in the
Externí odkaz:
https://doaj.org/article/33a9954239154f15806777cb1a6376fd
Autor:
Makoto Kurano, Daisuke Jubishi, Koh Okamoto, Hideki Hashimoto, Eri Sakai, Yoshifumi Morita, Daisuke Saigusa, Kuniyuki Kano, Junken Aoki, Sohei Harada, Shu Okugawa, Kent Doi, Kyoji Moriya, Yutaka Yatomi
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-18 (2022)
Abstract Background Among various complications of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), renal complications, namely COVID-19-associated kidney injuries, are related to the mortal
Externí odkaz:
https://doaj.org/article/8068e1f7d8d34721ab51aca8725df7b4
Publikováno v:
Cancer Medicine, Vol 11, Iss 18, Pp 3491-3507 (2022)
Abstract Background Numerous studies have investigated the possible involvement of eicosanoids, lysophospholipids, and sphingolipids in cancer. We considered that comprehensive measurement of these lipid mediators might provide a better understanding
Externí odkaz:
https://doaj.org/article/bc25b40aa99f490182c438d1fbc8f415
Autor:
Kenichi Shukuya, Yoshihumi Morita, Takashi Hisasue, Yoshikazu Ono, Satoshi Tomiyasu, Makoto Kurano, Yutaka Yatomi, Masami Tanaka
Publikováno v:
Practical Laboratory Medicine, Vol 36, Iss , Pp e00328- (2023)
a) Objectives: Urinalysis is one of the most common laboratory screening tests to detect problems in the renal and urinary system; however, they cannot detect atypical cells (Atyp.Cs). The Sysmex UF-5000, a fully automated urine particle analyzer, ca
Externí odkaz:
https://doaj.org/article/aabfee3f7f0d40ae96ab01c5ce1d5e2c