Zobrazeno 1 - 10
of 694
pro vyhledávání: '"Makoto, Kiso"'
Autor:
Wataru Masuda, Tomoko Yamakawa, Rieko Ajima, Katsuya Miyake, Toshifumi Umemiya, Kazuhiko Azuma, Jun-ichi Tamaru, Makoto Kiso, Puspa Das, Yumiko Saga, Kenji Matsuno, Motoo Kitagawa
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Notch signaling is an evolutionarily conserved mechanism required for numerous types of cell fate decisions in metazoans. It mediates short-range communication between cells with receptors and ligands, both of which are expressed on the cell
Externí odkaz:
https://doaj.org/article/db8e41c628a4412e85d3d2da141b5a7e
Autor:
Yuki Suganuma, Akihiro Imamura, Hiromune Ando, Makoto Kiso, Hiromu Takematsu, Takeshi Tsubata, Hideharu Ishida
Publikováno v:
Glycoconjugate Journal. 40:225-246
Autor:
Akiko Tsuchida, Motohiro Senda, Akihiro Ito, Seiichi Saito, Makoto Kiso, Takayuki Ando, Anne Harduin-Lepers, Akio Matsuda, Keiko Furukawa, Koichi Furukawa
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-15 (2018)
Abstract GalNAc-disialyl Lc4 (GalNAc-DSLc4) was reported as a novel antigen that associated with malignant features of renal cell cancers (RCCs). To clarify roles of GalNAc-DSLc4 in malignant properties of RCCs, we identified B4GalNAc-T2 as a respons
Externí odkaz:
https://doaj.org/article/6931623c8cee4e688a3f16eaa3d0c741
Publikováno v:
eLife, Vol 7 (2018)
The metameric structure in vertebrates is based on the periodic formation of somites from the anterior end of the presomitic mesoderm (PSM). The segmentation boundary is defined by the Tbx6 expression domain, whose anterior limit is determined by Tbx
Externí odkaz:
https://doaj.org/article/7234894fa3574d6c81306cdbe4b71e77
Autor:
Naoko Matsubara, Akihiro Imamura, Tatsuya Yonemizu, Chizuru Akatsu, Hongrui Yang, Akiharu Ueki, Natsuki Watanabe, Hajjaj Abdu-Allah, Nobutaka Numoto, Hiromu Takematsu, Shinobu Kitazume, Thomas F. Tedder, Jamey D. Marth, Nobutoshi Ito, Hiromune Ando, Hideharu Ishida, Makoto Kiso, Takeshi Tsubata
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Sialic acid-binding immunoglobulin-like lectins (Siglecs) are expressed in various immune cells and most of them carry signaling functions. High-affinity synthetic sialoside ligands have been developed for various Siglecs. Therapeutic potentials of t
Externí odkaz:
https://doaj.org/article/b295e45b1a9243a2b75066dfbe524004
Autor:
Megumi Yamagishi, Ritsuko Hosoda-Yabe, Hideki Tamai, Miku Konishi, Akihiro Imamura, Hideharu Ishida, Tomio Yabe, Hiromune Ando, Makoto Kiso
Publikováno v:
Marine Drugs, Vol 13, Iss 12, Pp 7250-7274 (2015)
LLG-3 is a ganglioside isolated from the starfish Linchia laevigata. To clarify the structure-activity relationship of the glycan of LLG-3 toward rat pheochromocytoma PC12 cells in the presence of nerve growth factor, a series of mono- to tetrasaccha
Externí odkaz:
https://doaj.org/article/ce526e434542440dbd5f813448d8f009
Publikováno v:
Molecules, Vol 18, Iss 12, Pp 15153-15181 (2013)
The development of a novel cyclic glucosyl ceramide cassette acceptor for efficient glycolipid syntheses was investigated. p-Methoxybenzyl (PMB) groups were selected as protecting groups at C2 and C3 of the glucose residue with the aim of improving t
Externí odkaz:
https://doaj.org/article/18534c9f8fed467fb11e97dfc0e19e0d
Publikováno v:
Molecules, Vol 19, Iss 1, Pp 414-437 (2013)
A new chemical approach to synthesizing human ABO histo-blood type 2 antigenic determinants was developed. N-Phthaloyl-protected lactosaminyl thioglycoside derived from lactulose via the Heyns rearrangement was employed to obtain a type 2 core disacc
Externí odkaz:
https://doaj.org/article/bbe3d263edeb4e7885a264e27c51195f
Autor:
Tomohiro Nohara, Akihiro Imamura, Maho Yamaguchi, Kazuya I. P. J. Hidari, Takashi Suzuki, Tatsuya Komori, Hiromune Ando, Hideharu Ishida, Makoto Kiso
Publikováno v:
Molecules, Vol 17, Iss 8, Pp 9590-9620 (2012)
A novel ganglioside bearing Neua2-3Gal and Neua2-6Gal structures as distal sequences was designed as a ligand for influenza A viruses. The efficient synthesis of the designed ganglioside was accomplished by employing the cassette coupling approach as
Externí odkaz:
https://doaj.org/article/fe118eba9e694e7d8777254dec51ef88
Autor:
Tatsuya Suzuki, Hiromune Ando, Hideharu Ishida, Akihiro Imamura, Makoto Kiso, Naoko Komura, Hidenori Tanaka, Rie Tamai, Junya Ogawa, Yoshiki Yamaguchi, Jun Uzawa, Chieka Hayashi
Publikováno v:
Organic Letters. 21:6393-6396
To expand the potential of Se-carbohydrates for multifunctional mimicry of sugars, herein we addressed the synthesis of the highly challenging and biologically significant Se-glycosides of sialic acid (Se-sialosides). An α-sialyl selenolate anion ge