Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Makoto, Kanematsu"'
Autor:
Makoto Kanematsu, Koichiro Fukuda, Tetsuji Kawamoto, David G. Cork, Shinichi Masada, Hirotsugu Usutani, Shotaro Miura
Publikováno v:
Organic & Biomolecular Chemistry. 17:8166-8174
Continuous flow-flash synthesis of a 2-bromobenzaldehyde derivative 18 as a key intermediate of a novel cholinergic muscarinic M1 positive allosteric modulator 1 bearing an isoindolin-1-one ring system as a pharmacophore has been achieved using flow
Autor:
Shotaro, Miura, Koichiro, Fukuda, Shinichi, Masada, Hirotsugu, Usutani, Makoto, Kanematsu, David G, Cork, Tetsuji, Kawamoto
Publikováno v:
Organicbiomolecular chemistry. 17(35)
Continuous flow-flash synthesis of a 2-bromobenzaldehyde derivative 18 as a key intermediate of a novel cholinergic muscarinic M
Autor:
Takatoshi Ito, Siyanda Mngadi, B.P. Watson, H. Ogasawara, Yasuo Yabe, Kosuke Sugimura, Ryogo Tadokoro, Makoto Kanematsu, Akio Funato, Shuhei Abe, Raymond Durrheim, Akimasa Ishida, Gerhard Hofmann, Mitsuya Higashi, Lourens Scheepers, Harumi Kato
Publikováno v:
Proceedings of the Ninth International Conference on Deep and High Stress Mining.
To demonstrate the possibility of stress measurement at depths of more than 3 km, in-situ stress states were determined around the source faults of three seismic events: a Mw2.2 seismic event at about 3.3 km below surface in Mponeng gold mine, a Mw3.
Autor:
Hiromasa Yokoe, Makoto Kanematsu, Takaaki Araki, Kozo Shishido, Tsukasa Ozawa, Masahiro Yoshida
Publikováno v:
Organic Letters. 15:200-203
A novel and highly diastereoselective intramolecular carbamoylketene/alkene [2 + 2] cycloaddition has been developed, and the methodology was successfully applied to the enantioselective syntheses of (-)-esermethole and Takayama's intermediate for (+
Publikováno v:
Synlett. 24:61-64
The second generation synthesis of (+)-aspermytin A and the first total synthesis of (–)-oblongolide C have been accomplished employing an intramolecular nitrile oxide–alkene [3+2] cycloaddition as the key step.
Autor:
Yuki Manabe, Hiromasa Yokoe, Masahiro Yoshida, Makoto Kanematsu, Akari Miyawaki, Daisuke Kikuchi, Kozo Shishido, Masu Niki
Publikováno v:
The Journal of Organic Chemistry. 77:8231-8243
A full account of the development of a novel type of the intramolecular Hosomi-Sakurai reactions of the substrates with a p-benzoquinone and an allylsilane moieties connected by an ether linkage is described. This transformation proceeds via an addit
Autor:
Makoto Kanematsu, Kozo Shishido
Publikováno v:
Journal of Synthetic Organic Chemistry, Japan. 70:1196-1205
Publikováno v:
Tetrahedron. 67:6753-6761
The enantioselective syntheses of the compounds with the assigned structures of the helibisabonols A and B have been accomplished. Using an enzymatic desymmetrization of the σ-symmetrical diol (route a) and a diastereoselective conjugate addition of
Publikováno v:
Tetrahedron. 67:4758-4766
The second-generation enantioselective synthesis of heliannuol A and the first enantioselective total synthesis of heliannuol K (via two routes) have both been accomplished efficiently; (heliannuol A, nine steps and 25% yield; heliannuol K, seven ste
Publikováno v:
Synthesis. 2009:2893-2904
An efficient total synthesis of (+)-bongkrekic acid, a potent apoptosis inhibitor, has been accomplished by employing a convergent strategy based on the Suzuki-Miyaura coupling of three fully functionalized segments.