Zobrazeno 1 - 10
of 729
pro vyhledávání: '"Makoto, Higuchi"'
Autor:
Koki Mimura, Jumpei Matsumoto, Daichi Mochihashi, Tomoaki Nakamura, Hisao Nishijo, Makoto Higuchi, Toshiyuki Hirabayashi, Takafumi Minamimoto
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Nonhuman primates (NHPs) exhibit complex and diverse behavior that typifies advanced cognitive function and social communication, but quantitative and systematical measure of this natural nonverbal processing has been a technical challenge.
Externí odkaz:
https://doaj.org/article/6093c6dd9364430580057493bfddded4
Autor:
Kenji Tagai, Harutsugu Tatebe, Sayo Matsuura, Zhang Hong, Naomi Kokubo, Kiwamu Matsuoka, Hironobu Endo, Asaka Oyama, Kosei Hirata, Hitoshi Shinotoh, Yuko Kataoka, Hideki Matsumoto, Masaki Oya, Shin Kurose, Keisuke Takahata, Masanori Ichihashi, Manabu Kubota, Chie Seki, Hitoshi Shimada, Yuhei Takado, Kazunori Kawamura, Ming-Rong Zhang, Yoshiyuki Soeda, Akihiko Takashima, Makoto Higuchi, Takahiko Tokuda
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-5 (2024)
Externí odkaz:
https://doaj.org/article/7c34e3413c9e47fabe9c650ddabe1a10
Autor:
Kei Oyama, Kei Majima, Yuji Nagai, Yukiko Hori, Toshiyuki Hirabayashi, Mark A. G. Eldridge, Koki Mimura, Naohisa Miyakawa, Atsushi Fujimoto, Yuki Hori, Haruhiko Iwaoki, Ken-ichi Inoue, Richard C. Saunders, Masahiko Takada, Noriaki Yahata, Makoto Higuchi, Barry J. Richmond, Takafumi Minamimoto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Primates must adapt to changing environments by optimizing their behavior to make beneficial choices. At the core of adaptive behavior is the orbitofrontal cortex (OFC) of the brain, which updates choice value through direct experience or kn
Externí odkaz:
https://doaj.org/article/f27f8d73cd764fdea074b296a315d225
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Temporal discounting, in which the recipient of a reward perceives the value of that reward to decrease with delay in its receipt, is associated with impulsivity and psychiatric disorders such as depression. Here, we investigate the role of
Externí odkaz:
https://doaj.org/article/49c7bf42b78340898ae30e79830cdb12
Autor:
Toshiyuki Hirabayashi, Yuji Nagai, Yuki Hori, Yukiko Hori, Kei Oyama, Koki Mimura, Naohisa Miyakawa, Haruhiko Iwaoki, Ken-ichi Inoue, Tetsuya Suhara, Masahiko Takada, Makoto Higuchi, Takafumi Minamimoto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Visual object memory is a fundamental element of various cognitive abilities, and the underlying neural mechanisms have been extensively examined especially in the anterior temporal cortex of primates. However, both macroscopic large-scale f
Externí odkaz:
https://doaj.org/article/02803be30c1241b9a4827729b6309ee6
Autor:
Mari Miyata, Keisuke Takahata, Yasunori Sano, Yasuharu Yamamoto, Shin Kurose, Manabu Kubota, Hironobu Endo, Kiwamu Matsuoka, Kenji Tagai, Masaki Oya, Kosei Hirata, Fumie Saito, Masaru Mimura, Koji Kamagata, Shigeki Aoki, Makoto Higuchi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Cognitive dysfunction, especially memory impairment, is a typical clinical feature of long-term symptoms caused by repetitive mild traumatic brain injury (rmTBI). The current study aims to investigate the relationship between regional brain
Externí odkaz:
https://doaj.org/article/b9e19ea8ec664b4aa1f7cb2f3bf3b27c
Autor:
Naruhiko Sahara, Makoto Higuchi
Publikováno v:
FEBS Open Bio, Vol 14, Iss 2, Pp 165-180 (2024)
Tauopathies, characterized by fibrillar tau accumulation in neurons and glial cells, constitute a major neuropathological category of neurodegenerative diseases. Neurofibrillary tau lesions are strongly associated with cognitive deficits in these dis
Externí odkaz:
https://doaj.org/article/a10cf597887049ffa80dbcf1db61fa0d
Autor:
Yoshimasa Matsumura, Alvin Tanudjaja, Mizuki Fukushima, Makoto Higuchi, Shin Ogino, Makoto Ishidoshiro, Yasuyuki Irie, Hiroaki Imoto, Kensuke Naka, Ryoyu Hifumi, Shinsuke Inagi, Ikuyoshi Tomita
Publikováno v:
Designed Monomers and Polymers, Vol 26, Iss 1, Pp 190-197 (2023)
The donor-acceptor type π-conjugated polymers having heterole units were prepared by the reaction of a regioregular organometallic polymer having both reactive titanacyclopentadiene and electron-donor thiophene-2,5-diyl units in the main chain with
Externí odkaz:
https://doaj.org/article/7e8f97d7d8c841a19da58457da6cfb08
Autor:
Hiroshi Ikenuma, Aya Ogata, Hiroko Koyama, Bin Ji, Hideki Ishii, Takashi Yamada, Junichiro Abe, Chie Seki, Yuji Nagai, Masanori Ichise, Takafumi Minamimoto, Makoto Higuchi, Ming-Rong Zhang, Takashi Kato, Kengo Ito, Masaaki Suzuki, Yasuyuki Kimura
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 8, Iss 1, Pp 1-16 (2023)
Abstract Background Receptor interacting protein kinase 1 (RIPK1) is a serine/threonine kinase, which regulates programmed cell death and inflammation. Recently, the involvement of RIPK1 in the pathophysiology of Alzheimer’s disease (AD) has been r
Externí odkaz:
https://doaj.org/article/cfeab7411ca541868cfb1ec34b86e244
Autor:
Joachim Strobel, Elham Yousefzadeh-Nowshahr, Katharina Deininger, Karl Peter Bohn, Christine A. F. von Arnim, Markus Otto, Christoph Solbach, Sarah Anderl-Straub, Dörte Polivka, Patrick Fissler, Gerhard Glatting, Matthias W. Riepe, Makoto Higuchi, Ambros J. Beer, Albert Ludolph, Gordon Winter
Publikováno v:
Biomedicines, Vol 12, Iss 7, p 1460 (2024)
Accurately diagnosing Alzheimer’s disease (AD) and frontotemporal lobar degeneration (FTLD) is challenging due to overlapping symptoms and limitations of current imaging methods. This study investigates the use of [11C]PBB3 PET/CT imaging to visual
Externí odkaz:
https://doaj.org/article/d87668f1d75d4efda34c8e53925f4409