Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Makoto, FUKUMATSU"'
Publikováno v:
Clinical Ophthalmology.
Masahiko Shimura,1 Makoto Fukumatsu,2 Jun Tsujimura,2 Kazufumi Hirano,2 Toshiyuki Sunaya3 On behalf of the Participating Investigators1Department of Ophthalmology, Tokyo Medical University Hachioji Medical Center, Tokyo, Japan; 2Medical Affairs & Pha
Autor:
Yuko Yoshikawa, Toru Yanagawa, Akira Kakizuka, Michinaga Ogawa, Minsoo Kim, Trinad Chakraborty, Elizabeth Sztul, Makoto Fukumatsu, Torsten Hain, Tetsuro Ishii, Ichiro Nakagawa, Hitomi Mimuro, Mitsutaka Yoshida, Chihiro Sasakawa
Publikováno v:
Nature Cell Biology. 11:1233-1240
Autophagy degrades unnecessary organelles and misfolded protein aggregates, as well as cytoplasm-invading bacteria. Nevertheless, the bacteria Listeria monocytogenes efficiently escapes autophagy. We show here that recruitment of the Arp2/3 complex a
Autor:
Dangeruta Kersulyte, Hanako Morikawa, Makoto Fukumatsu, Shigeo Koyasu, Robert H. Gilman, Douglas E. Berg, Nozomi Ishijima, Hitomi Mimuro, Shigenori Nagai, Chihiro Sasakawa, Masato Suzuki, Kotaro Kiga
Publikováno v:
Cell Host & Microbe. 5:23-34
SummaryCagA, a major virulence factor of Helicobacter pylori (Hp), is delivered into gastric epithelial cells and exists in phosphorylated and nonphosphorylated forms. The biological activity of the phosphorylated form is well established; however, f
Autor:
Makoto, FUKUMATSU, Yukihiro, UENO, Ayako, OGASAWARA, Toshihiko, WATANABE, Takeshi, MIKAMI, Tatsuji, MATSUMOTO
Publikováno v:
東北薬科大学研究誌. 50:155-159
Candida albicans generally grows in hyphal form in RPMI-1640 medium. However, transformation of hyphal form to yeast form is observed by increasing of the cell density in RPMI-1640 medium. Intracellular Ca^ was increased in yeast growth condition (hi
Autor:
Ayako Ogasawara, Takeshi Mikami, Makoto Fukumatsu, Toshihiko Watanabe, Yukihiro Ueno, Tatsuzi Matsumoto
Publikováno v:
Biological and Pharmaceutical Bulletin. 27:890-892
Candida albicans generally grows in hyphae form in RPMI1640 medium. However, addition of 1,4-diamino-2-butanone (DAB), a competitive inhibitor of ornithine decarboxylase, decreased the amount of polyamines in C. albicans, and induced the proliferatio
Publikováno v:
Virulence. 3(6)
Many invasive intracellular bacterial pathogens such as Shigella and Listeria monocytogenes can spread from cell to cell during infection, and this spreading is an important pathogenic mechanism to expand their replicative niches. However, it is stil
Autor:
Tomohiro Koyama, Kotaro Kiga, Hitomi Mimuro, Shigeru Kakuta, Hiroshi Ashida, Takahiro Nagatake, Yuko Yoshikawa, Michinaga Ogawa, Magdalena Kawalec, Jean-Marc Reichhart, Chihiro Sasakawa, Yoshiyuki Goto, Taira Kobayashi, Makoto Fukumatsu, Mitsutaka Yoshida, Shinya Nagai, Hiroshi Kiyono, Zhenzi Piao
Publikováno v:
Cell Host & Microbe. (5):376-389
SummarySelective autophagy of bacterial pathogens represents a host innate immune mechanism. Selective autophagy has been characterized on the basis of distinct cargo receptors but the mechanisms by which different cargo receptors are targeted for au
Autor:
Minsoo Kim, Chihiro Sasakawa, Satoko Arakawa, Kazuhisa Nakayama, Masato Suzuki, Makoto Fukumatsu, Shigeomi Shimizu, Hitomi Mimuro, Michinaga Ogawa
Publikováno v:
Virulence
SummaryBacteria move between cells in the epithelium using a sequential pseudopodium-mediated process but the underlying mechanisms remain unclear. We show that during cell-to-cell movement, Shigella-containing pseudopodia target epithelial tricellul