Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Mako Yasuda-Yamahara"'
Autor:
Yoshimi Imamura-Uehara, Mako Yasuda-Yamahara, Shogo Kuwagata, Kosuke Yamahara, Mamoru Yoshibayashi, Yuki Tanaka-Sasaki, Akio Shimizu, Hisakazu Ogita, Masami Chin-Kanasaki, Shinji Kume
Publikováno v:
Biochemistry and Biophysics Reports, Vol 37, Iss , Pp 101607- (2024)
Renal artery stenosis-induced chronic renal ischemia is an important cause of renal dysfunction, especially in older adults, and its incidence is currently increasing. To elucidate the mechanisms underlying chronic renal hypoperfusion-induced kidney
Externí odkaz:
https://doaj.org/article/c46db925d33343ed9e64a58237eff28d
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 321 (2021)
Diabetic kidney disease (DKD) is the leading cause of end-stage renal disease and the number of patients affected is increasing worldwide. Thus, there is a need to establish a new treatment for DKD to improve the renal prognosis of diabetic patients.
Externí odkaz:
https://doaj.org/article/670e670a65f24d27886728b94e5ce32e
Autor:
Mako Yasuda-Yamahara, Manuel Rogg, Kosuke Yamahara, Jasmin I Maier, Tobias B Huber, Christoph Schell
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200487 (2018)
Podocytes are highly-specialized epithelial cells essentially required for the generation and the maintenance of the kidney filtration barrier. This elementary function is directly based on an elaborated cytoskeletal apparatus establishing a complex
Externí odkaz:
https://doaj.org/article/417c490aeecf4518a44a609e89396886
Autor:
Issei Tomita, Hiroaki Tsuruta, Mako Yasuda‐Yamahara, Kosuke Yamahara, Shogo Kuwagata, Yuki Tanaka‐Sasaki, Masami Chin‐Kanasaki, Yukihiro Fujita, Eiichiro Nishi, Hideki Katagiri, Hiroshi Maegawa, Shinji Kume
Publikováno v:
Aging Cell.
Accumulating evidence suggests health benefits of ketone bodies, and especially for longevity. However, the precise role of endogenous ketogenesis in mammalian life span, and the safety and efficacy of the long-term exogenous supplementation of keton
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55500c0336a400b1c5c41dddf0242bf9
https://doi.org/10.1111/acel.13833
https://doi.org/10.1111/acel.13833
Autor:
Yoshihiko Fujino, Mako Yasuda-Yamahara, Yuki Tanaka-Sasaki, Shogo Kuwagata, Kosuke Yamahara, Atsuko Tagawa, Masami Chin-Kanasaki, Motoko Yanagita, Hiroshi Maegawa, Shinji Kume
Publikováno v:
Biochemical and biophysical research communications. 620:15-20
Lipoprotein lipase (LPL) is an enzyme that catalyzes the hydrolysis of circulating triglyceride and the transport of fatty acids into cells. Its activity is positively regulated by insulin, and insulin resistance is associated with low LPL activity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4434302144e79201d69802a8c59bdb97
http://hdl.handle.net/10422/00013367
http://hdl.handle.net/10422/00013367
Autor:
Masami Chin-Kanasaki, Naoko Takeda, Hiroshi Maegawa, Yukihiro Fujita, Kousuke Yamahara, Kazunobu Sawai, Shin-ichi Araki, Mako Yasuda-Yamahara, Shinji Kume, Norihisa Osawa
Publikováno v:
CEN Case Rep
A 43-year-old male patient on maintenance hemodialysis had an enhanced computed tomography scan examination with iohexol for the first time 10 min before regular hemodialysis therapy. At the start of hemodialysis, no symptoms were observed, and the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca31ed1542e808835f24a613d969b9a
https://doi.org/10.1007/s13730-020-00468-8
https://doi.org/10.1007/s13730-020-00468-8
Autor:
Norihisa Osawa, Hiroshi Maegawa, Yuki Nakae, Hideki Yokoi, Naoko Takeda, Mako Yasuda-Yamahara, Katsuhiko Asanuma, Masashi Mukoyama, Masami Chin-Kanasaki, Mamoru Yoshibayashi, Shin-ichi Araki, Kosuke Yamahara, Shinji Kume
Publikováno v:
Biochemical and Biophysical Research Communications. 525:319-325
To examine the cell-protective role of podocyte autophagy against glomerular endothelial dysfunction in diabetes, we analyzed the renal phenotype of tamoxifen (TM)-inducible podocyte-specific Atg5-deficient (iPodo-Atg5-/-) mice with experimental endo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef55c7b5efa74915f2591cab646f869
https://doi.org/10.1016/j.bbrc.2020.02.088
https://doi.org/10.1016/j.bbrc.2020.02.088
Autor:
Shinji Kume, Mako Yasuda-Yamahara, Yoshimi Imamura-Uehara, Shogo Kuwagata, Kosuke Yamahara, Naoko Takeda, Masami Chin-Kanasaki, Koichi Kato, Seiko Ohno, Yoshihisa Nakagawa, Hiroshi Maegawa
Publikováno v:
Internal medicine (Tokyo, Japan). 61(20)
Fabry disease is an inherited lysosomal disorder caused by mutations in the alpha-galactosidase A gene. We herein report a Fabry disease patient with enzyme replacement therapy (ERT)-resistant proteinuria who showed improvement in the estimated glome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f98ddd37e2231ac84e8d42d6de166b
https://pubmed.ncbi.nlm.nih.gov/35283375
https://pubmed.ncbi.nlm.nih.gov/35283375
Autor:
Makoto Tagaya, Shinji Kume, Mako Yasuda-Yamahara, Shogo Kuwagata, Kosuke Yamahara, Naoko Takeda, Yuki Tanaka, Masami Chin-Kanasaki, Yuki Nakae, Hideki Yokoi, Masashi Mukoyama, Naotada Ishihara, Masatoshi Nomura, Shin-ichi Araki, Hiroshi Maegawa
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1868(5)
Aims:Identifying the mechanisms that underlie progression from endothelial damage to podocyte damage, which leads to massive proteinuria, is an urgent issue that must be clarified to improve renal outcome in diabetic kidney disease (DKD). We aimed to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c3b596cd885365bdbd3cf6fd93231a
http://hdl.handle.net/10422/00013229
http://hdl.handle.net/10422/00013229
Autor:
Nor Idayu A. Rahman, Rasel Molla, Akira Sato, Hiroshi Maegawa, Akio Shimizu, Joanne Ern Chi Soh, Mohammad Khusni B Ahmat Amin, Le Kim Chi Nguyen, Masahiro Komeno, Nao Kokami, Mako Yasuda-Yamahara, Shinji Kume, Hisakazu Ogita, Yoshihiro Asano, Xiaoling Pang
Publikováno v:
The Journal of Biological Chemistry
Diabetes mellitus (DM) causes injury to tissues and organs, including to the heart and kidney, resulting in increased morbidity and mortality. Thus, novel potential therapeutics are continuously required to minimize DM-related organ damage. We have p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e278a406b4efe8fb929d3f147cf014
https://pubmed.ncbi.nlm.nih.gov/33971198
https://pubmed.ncbi.nlm.nih.gov/33971198