Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Makiri Kawasaki"'
Autor:
Makiri Kawasaki, Rushd F. M. Al-Shama, Fransisca A. Nariswari, Benedetta Fabrizi, Nicoline W. E. van den Berg, Robin Wesselink, Jolien Neefs, Eva R. Meulendijks, Sarah W. E. Baalman, Antoine H. G. Driessen, Joris R. de Groot
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Atrial fibrosis serves as an arrhythmogenic substrate in atrial fibrillation (AF) and contributes to AF persistence. Treating atrial fibrosis is challenging because atrial fibroblast activity is multifactorial. We hypothesized that the prima
Externí odkaz:
https://doaj.org/article/6b9feb6c08294774b486b07070095f8e
Autor:
Eva R. Meulendijks, Rushd F. M. Al-Shama, Makiri Kawasaki, Benedetta Fabrizi, Jolien Neefs, Robin Wesselink, Auriane C. Ernault, Sander Piersma, Thang V. Pham, Connie R. Jimenez, Jaco C. Knol, Wim J. P. van Boven, Antoine H. G. Driessen, Tim A. C. de Vries, Britt van der Leeden, Hans W. M. Niessen, Onno J. de Boer, Sébastien P. J. Krul, Joris R. de Groot
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Epicardial adipose tissue (EAT) secretome induces fibrosis. Fibrosis, primarily extracellular matrix (ECM) produced by fibroblasts, creates a substrate for atrial fibrillation (AF). Whether the EAT secretome from patients with AF
Externí odkaz:
https://doaj.org/article/b6cf7114ad5148eaab99d938a3be13c0
Autor:
Auriane C. Ernault, Makiri Kawasaki, Benedetta Fabrizi, Pablo Montañés-Agudo, Shirley C. M. Amersfoorth, Rushd F. M. Al-Shama, Ruben Coronel, Joris R. De Groot
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Background: Atrial fibrosis plays an important role in the development and persistence of atrial fibrillation by promoting reentry. Primary cilia have been identified as a regulator of fibroblasts (FB) activation and extracellular matrix (ECM) deposi
Externí odkaz:
https://doaj.org/article/ebebcfbda4be4769afb87a318b921dd0
Autor:
Robin Wesselink, Bente Mossink, Eva R. Meulendijks, Nicoline W. E. van den Berg, Jolien Neefs, Makiri Kawasaki, Benedetta Fabrizi, Femke R. Piersma, Rushd F. M. Al-Shama, Tim A. C. de Vries, Jonas S. S. G. de Jong, Wim Jan P. van Boven, Antoine H. G. Driessen, Joris R. de Groot
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 7, p 2650 (2023)
Introduction. Atrial fibrillation (AF) is more prevalent in men than in women. However, women with AF are more symptomatic, have a worse quality of life, a higher stroke risk and may therefore benefit most from ablation. In this study we aim to ident
Externí odkaz:
https://doaj.org/article/164c5ad6487b4774a45b96b65cdf1ce7
Autor:
Makiri Kawasaki, Eva R. Meulendijks, Nicoline W. E. van den Berg, Fransisca A. Nariswari, Jolien Neefs, Robin Wesselink, Sarah W. E. Baalman, Aldo Jongejan, Tim Schelfhorst, Sander R. Piersma, Thang V. Pham, Wim J. P. van Boven, Antoine H. G. Driessen, Connie R. Jimenez, Joris R. de Groot
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Despite our expanding knowledge about the mechanism underlying atrial fibrillation (AF), the interplay between the biological events underlying AF remains incompletely understood. This study aimed to identify the functionally enriched gene-s
Externí odkaz:
https://doaj.org/article/a465c257cf0a4202abba46855f955d7d
Autor:
Nicoline W. E. van den Berg, Makiri Kawasaki, Benedetta Fabrizi, Fransisca A. Nariswari, Arianne C. Verduijn, Jolien Neefs, Robin Wesselink, Rushd F. M. Al‐Shama, Allard C. van der Wal, Onno J. de Boer, Jan Aten, Antoine H. G. Driessen, Aldo Jongejan, Joris R. de Groot
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 11, Pp n/a-n/a (2021)
Abstract Background Improved understanding of the interconnectedness of structural remodeling processes in atrial fibrillation (AF) in patients could identify targets for future therapies. Methods We present transcriptome sequencing of atrial tissues
Externí odkaz:
https://doaj.org/article/1856597343d24eb6845f5da16fe68c38
Autor:
Arie O. Verkerk, Gerard A. Marchal, Jan G. Zegers, Makiri Kawasaki, Antoine H. G. Driessen, Carol Ann Remme, Joris R. de Groot, Ronald Wilders
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Introduction: Atrial fibrillation (AF) is the most common cardiac arrhythmia. Consequently, novel therapies are being developed. Ultimately, the impact of compounds on the action potential (AP) needs to be tested in freshly isolated human atrial myoc
Externí odkaz:
https://doaj.org/article/bcf3988a253842a6aaf10994a35a7445
Autor:
Simona Casini, Gerard A. Marchal, Makiri Kawasaki, Benedetta Fabrizi, Robin Wesselink, Fransisca A. Nariswari, Jolien Neefs, Nicoline W.E. van den Berg, Antoine H.G. Driessen, Joris R. de Groot, Arie O. Verkerk, Carol Ann Remme
Publikováno v:
Canadian journal of cardiology. Pulsus Group Inc.
Background: The cellular mechanisms underlying progression from paroxysmal to persistent atrial fibrillation (AF) are not fully understood, but alterations in (late) sodium current (INa) have been proposed. Human studies investigating electrophysiolo
Autor:
Auriane C. Ernault, Arie O. Verkerk, Jason D. Bayer, Kedar Aras, Pablo Montañés-Agudo, Rajiv A. Mohan, Marieke Veldkamp, Mathilde R. Rivaud, Rosan de Winter, Makiri Kawasaki, Shirley C.M. van Amersfoorth, Eva R. Meulendijks, Antoine H.G. Driessen, Igor R. Efimov, Joris R. de Groot, Ruben Coronel
Publikováno v:
Heart rhythm, 19(9), 1461-1470. Elsevier
Background: Epicardial adipose tissue (EAT) accumulation is associated with cardiac arrhythmias. The effect of EAT secretome (EATs) on cardiac electrophysiology remains largely unknown. Objective: The purpose of this study was to investigate the arrh
Autor:
Eva R. Meulendijks, Sébastien P.J. Krul, Sarah W. Baalman, Tim A.C. de Vries, Robin Wesselink, Auriane C. Ernault, Makiri Kawasaki, Rushd Al-Shama, Jolien Neefs, Jacqueline Limpens, Joris R. de Groot
Publikováno v:
Trends in Cardiovascular Medicine.
Obesity increases the risk of atrial fibrillation (AF), potentially through proteins secreted by adipose tissue (AT) that affect atrial electrical and structural remodeling. We aim to give a comprehensive overview of circulating AT proteins that are