Výsledky vyhledávání - "Makio Tamura"

Autophagy activators stimulate the removal of advanced glycation end products in human keratinocytes

Autor: Makio Tamura, Bradley B. Jarrold, X. Wang, B. Fang, J. Chen, Timothy Laughlin, A. Matsubara, L. Li, G. Deng, W. Zhao, Tomohiro Hakozaki, Y. Tan

Publikováno v: Journal of the European Academy of Dermatology and Venereology. 34:12-18

Background The accumulation of advanced glycation end products (AGEs) can impact cellular homoeostasis and protein structure, thus is implicated in numerous skin conditions including yellow, dull appearance. AGE formation is irreversible; thus, under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cfc39021860fa6c00c39cc465482d2e
https://doi.org/10.1111/jdv.16453

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Combinations of Peptides Synergistically Activate the Regenerative Capacity of Skin Cells In Vitro

Autor: Michael J. Flagler, Joseph D. Sherrill, Lisa Ann Mullins, Bradley B. Jarrold, Kim Kozak, Tim Laughlin, Rachel L. Adams, Makio Tamura, Kellen Cresswell, Julie Ashe, Scott Michael Hartman, Robert J. Isfort

To explore synergistic effects related to skin regeneration, peptides with distinct biological mechanisms of action were evaluated in combination with different skin cell lines in the presence or absence of niacinamide (Nam). Furthermore, the synergi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab911a2481995cab36e2fc25ffc4c7c
https://doi.org/10.1101/2021.07.07.451479

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Niacinamide mitigates SASP-related inflammation induced by environmental stressors in human epidermal keratinocytes and skin

Autor: John Erich Oblong, Ben C. Hulette, Catherine E. Mack, Christina Yan Ru Tan, Timothy Laughlin, Makio Tamura, Sophie Bellanger, Joseph D. Sherrill, Malgorzata Morenc, John Crist Bierman

Publikováno v: International journal of cosmetic scienceReferences. 42(5)

Objective To evaluate whether niacinamide (Nam) can mitigate production of inflammatory and senescence-related biomarkers induced by environmental stressors. Methods Human epidermal keratinocytes were exposed to UVB, urban dust, diesel exhaust and ci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9aafc1aea67875946c590f1e3258f90
https://pubmed.ncbi.nlm.nih.gov/32657437

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Nicotinamide (aka Niacinamide) Mitigates SASP-Related Inflammation Induced by Environmental Stressors in Human Epidermal Keratinocytes

Autor: Makio Tamura, Catherine E. Mack, Malgorzata Morenc, John Erich Oblong, Sophie Bellanger, Christina Yan Ru Tan, Ben C. Hulette, Timothy Laughlin, John Crist Bierman

Daily exposure of skin to environmental stressors leads to molecular and morphological changes ascribed as premature aging. These stressors include solar radiation, industrial pollution, fossil fuel and carbon emissions, which cause cellular damage t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d76f6a463ae041a1a712d1bff8350850
https://doi.org/10.20944/preprints202003.0192.v1

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Age-induced and photoinduced changes in gene expression profiles in facial skin of Caucasian females across 6 decades of age

Publikováno v: Journal of the American Academy of Dermatology. 78(1)

Background Intrinsic and extrinsic factors, including ultraviolet irradiation, lead to visible signs of skin aging. Objective We evaluated molecular changes occurring in photoexposed and photoprotected skin of white women 20 to 74 years of age, some

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e347eed34a324bfaa6ddcb17fe48ad93
https://pubmed.ncbi.nlm.nih.gov/29146147

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What women want - quantifying the perception of hair amount: an analysis of hair diameter and density changes with age in caucasian women

Autor: R.S. Youngquist, C. Robbins, Paradi Mirmirani, Makio Tamura, T. Filloon, M.P. Birch, Fangyi Luo, Andrew G. Messenger, Thomas L. Dawson

Publikováno v: British Journal of Dermatology. 167:324-332

Summary Background It has long been known that women lose satisfaction with their hair with ageing. Our data show that caucasian women perceive a decrease in hair amount in their mid 40s with a further decrease in the mid to late 50s, which leads to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8532d583c85b462da53895ded5003cb1
https://doi.org/10.1111/j.1365-2133.2012.11010.x

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Dandruff/seborrhoeic dermatitis is characterized by an inflammatory genomic signature and possible immune dysfunction: transcriptional analysis of the condition and treatment effects of zinc pyrithione

Autor: Jay P. Tiesman, Makio Tamura, J. Henry, K.J. Mills, Jun Xu, Ping Hu

Publikováno v: British Journal of Dermatology. 166:33-40

Summary Background Dandruff/seborrhoeic dermatitis is a common scalp condition that is characterized by flakes, pruritus and sometimes mild erythema. These symptoms reflect tissue level events that are poorly understood at the molecular level. Object

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5845782dfb9b0c5fb11288414fdcaca9
https://doi.org/10.1111/j.1365-2133.2012.10863.x

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Microbial genotype–phenotype mapping by class association rule mining

Autor: Patrik D'haeseleer, Makio Tamura

Publikováno v: Bioinformatics

Motivation: Microbial phenotypes are typically due to the concerted action of multiple gene functions, yet the presence of each gene may have only a weak correlation with the observed phenotype. Hence, it may be more appropriate to examine co-occurre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642b8c4c1ae326de9a9c7c7eb264fb7d
http://europepmc.org/articles/PMC2718668

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