Zobrazeno 1 - 10
of 173
pro vyhledávání: '"Makio Ogawa"'
Autor:
Keith L. Kirkwood, Ying Xiong, Meenal Mehrotra, Uday K Baliga, Makio Ogawa, In-Hong Kang, Katie R. Wilson, Beneta Parthiban, Shikhar Mehrotra, Amanda C. LaRue, Krishnamurthy Thyagarajan, Shilpak Chatterjee, James L. Borke, Emily L. Moore
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
While earlier studies have suggested that cells positive for hematopoietic markers can be found in dental tissues, it has yet to be confirmed. To conclusively demonstrate this, we utilized a unique transgenic model in which all hematopoietic cells ar
Publikováno v:
Best Practice & Research Clinical Haematology. 28:73-80
Almost two decades ago, a number of cell culture and preclinical transplantation studies suggested the striking concept of the tissue-reconstituting ability of hematopoietic stem cells (HSCs). While this heralded an exciting time of radically new the
Publikováno v:
Blood Cells, Molecules, and Diseases. 50:41-49
Repair of bone fracture requires recruitment and proliferation of stem cells with the capacity to differentiate to functional osteoblasts. Given the close association of bone and bone marrow (BM), it has been suggested that BM may serve as a source o
Autor:
Yong Z. Gong, Masahiro Masuya, Demetri D. Spyropoulos, Gary S. Gilkeson, Christopher R. Williams, Omar Moussa, Amanda C. LaRue, Xian K. Zhang, Makio Ogawa, Dennis K. Watson, Romeo S. Abangan
Publikováno v:
Molecular and Cellular Biology. 30:5194-5206
Targeted disruption of the Fli1 gene results in embryonic lethality. To dissect the roles of functional domains in Fli1, we recently generated mutant Fli1 mice that express a truncated Fli1 protein (Fli1(ΔCTA)) that lacks the carboxy-terminal regula
Publikováno v:
Experimental Hematology. 38:603-608
Objective To develop an efficient method for single hematopoietic stem cell (HSC) transplantation for high-level hematopoietic engraftment. Materials and Methods We combined single-cell sorting with short-term culture of putative HSCs. Mouse bone mar
Autor:
Makio Ogawa, John R. Wingard, Christopher J. Drake, Paul A. Fleming, Su Yang, Hitoshi Minamiguchi, Fumihiko Ishikawa
Publikováno v:
Pancreas. 36:e30-e35
Objectives Pancreatic acinar cells and hepatocytes arise from the same cell population located within the embryonic endoderm. It has been reported that a multipotent population of liver cells is capable of differentiating into pancreatic cells. Recen
Publikováno v:
Blood. 108:2893-2896
Tissue fibroblasts/myofibroblasts play a key role in growth factor secretion, matrix deposition, and matrix degradation, and therefore are important in many pathologic processes. Regarding the origin of tissue fibroblasts/myofibroblasts, a number of
Autor:
Roger R. Markwald, Christopher J. Drake, Richard P. Visconti, Tim C. McQuinn, Paul A. Fleming, Amanda C. LaRue, Hitoshi Minamiguchi, Yasuhiro Ebihara, Makio Ogawa, Masahiro Masuya
Publikováno v:
Circulation Research. 98:690-696
Recent studies evaluating hematopoietic stem cell (HSC) potential raise the possibility that, in addition to embryonic sources, adult valve fibroblasts may be derived from HSCs. To test this hypothesis, we used methods that allow the potential of a s
Autor:
Masahiro Masuya, Hitoshi Minamiguchi, Christopher J. Drake, Paul A. Fleming, Makio Ogawa, Yasuhiro Ebihara, Richard P. Visconti, Amanda C. LaRue
Publikováno v:
Experimental Hematology. 34:219-229
Objective Using transplantation of a clonal population of cells derived from a single hematopoietic stem cell (HSC) of transgenic enhanced green fluorescent protein (EGFP) mice, we have documented the hematopoietic origin of myofibroblasts, such as k
Publikováno v:
Annals of the New York Academy of Sciences. 938:139-145
For more than a decade it was believed that hematopoietic stem cells express CD34. However, this dogma was recently challenged by the observation that stem cells of normal adult mice are CD34-. In order to clarify the controversy, we carried out syst