Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Makiko Mochizuki"'
Autor:
Makiko Mochizuki, Hideki Maeda
Publikováno v:
Frontiers in Medical Technology, Vol 6 (2024)
BackgroundAlthough a variety of drug delivery devices have been launched in recent years, few studies have comprehensively investigated the market trends of combination drugs and medical devices approved or certified in Japan and the regulatory chall
Externí odkaz:
https://doaj.org/article/c5c4a1e49a75479b9dce29d3f2619175
Autor:
Narasaiah Kovuru, Makiko Mochizuki-Kashio, Theresa Menna, Greer Jeffrey, Yuning Hong, Young me Yoon, Zhe Zhang, Peter Kurre
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Demand-adjusted and cell type specific rates of protein synthesis represent an important safeguard for fate and function of long-term hematopoietic stem cells. Here, we identify increased protein synthesis rates in the fetal hematopoietic st
Externí odkaz:
https://doaj.org/article/1139306fd82a425d9bdafd123ec40c60
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Externí odkaz:
https://doaj.org/article/0f9dd1beb0a54e77acb8df97016ee879
Autor:
Makiko Mochizuki-Kashio, Noriko Otsuki, Kota Fujiki, Sherif Abdelhamd, Peter Kurre, Markus Grompe, Atsushi Iwama, Kayoko Saito, Ayako Nakamura-Ishizu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Fanconi Anemia (FA) is an inherited bone marrow (BM) failure disorder commonly diagnosed during school age. However, in murine models, disrupted function of FA genes leads to a much earlier decline in fetal liver hematopoietic stem cell (FL HSC) numb
Externí odkaz:
https://doaj.org/article/1549e69d8d5b4516bf6cdb405a36854c
Autor:
Kazumasa Aoyama, Motohiko Oshima, Shuhei Koide, Emi Suzuki, Makiko Mochizuki-Kashio, Yuko Kato, Shiro Tara, Daisuke Shinoda, Nobuhiro Hiura, Yaeko Nakajima-Takagi, Goro Sashida, Atsushi Iwama
Publikováno v:
iScience, Vol 9, Iss , Pp 161-174 (2018)
Summary: Polycomb repressive complex (PRC) 2 represses transcription through histone H3K27 trimethylation (H3K27me3). We previously reported that the hematopoietic-cell-specific deletion of Ezh2, encoding a PRC2 enzyme, induced myelodysplastic syndro
Externí odkaz:
https://doaj.org/article/3b90d27dcc1247fc9e8e1ebcd0d352b0
Autor:
Satoru Miyagi, Shuhei Koide, Atsunori Saraya, George R. Wendt, Motohiko Oshima, Takaaki Konuma, Satoshi Yamazaki, Makiko Mochizuki-Kashio, Yaeko Nakajima-Takagi, Changshan Wang, Tetsuhiro Chiba, Issay Kitabayashi, Hiromitsu Nakauchi, Atsushi Iwama
Publikováno v:
Stem Cell Reports, Vol 2, Iss 2, Pp 145-152 (2014)
TIF1β is a transcriptional corepressor that recruits repressive chromatin modifiers to target genes. Its biological function and physiological targets in somatic stem cells remain largely unknown. Here, we show that TIF1β is essential for the maint
Externí odkaz:
https://doaj.org/article/77fc2e1406ad480c8eee1653a4d729bb
Autor:
Changshan Wang, Motohiko Oshima, Goro Sashida, Takahisa Tomioka, Nagisa Hasegawa, Makiko Mochizuki-Kashio, Yaeko Nakajima-Takagi, Yoichiro Kusunoki, Seishi Kyoizumi, Kazue Imai, Kei Nakachi, Atsushi Iwama
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132041 (2015)
Precise understanding of radiation effects is critical to develop new modalities for the prevention and treatment of radiation-induced damage. We previously reported that non-lethal doses of X-ray irradiation induce DNA damage in human hematopoietic
Externí odkaz:
https://doaj.org/article/e4c7b57f27af4e25b1c48c88079e5b37
Autor:
Taito Nishino, Changshan Wang, Makiko Mochizuki-Kashio, Mitsujiro Osawa, Hiromitsu Nakauchi, Atsushi Iwama
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24298 (2011)
BACKGROUND: Human cord blood (hCB) is the main source of hematopoietic stem and progenitor cells (HSCs/PCs) for transplantation. Efforts to overcome relative shortages of HSCs/PCs have led to technologies to expand HSCs/PCs ex vivo. However, methods
Externí odkaz:
https://doaj.org/article/d827036a358848a1b652e7a7f70caaed
Autor:
Kovuru, Narasaiah, Makiko Mochizuki-Kashio, Menna, Theresa, Jeffrey, Greer, Yuning Hong, Young me Yoon, Zhe Zhang, Kurre, Peter
Publikováno v:
Nature Communications; 2/29/2024, Vol. 15 Issue 1, p1-15, 15p, 2 Diagrams, 3 Graphs
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7026765801500927d935d0ab5592fe33
https://doi.org/10.1016/b978-0-12-821618-7.00077-8
https://doi.org/10.1016/b978-0-12-821618-7.00077-8
