Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Makiko Hirose"'
Autor:
Shuho Hori, Tsuyoshi Shimmura, Makiko Hirose, Masayuki Tanaka, Chinobu Okamoto, Mari Iwahara, Shuichi Ito, Atsushi Matsumoto, Ken-ichi Yayou, Azusa Yatsushiro
Publikováno v:
Animal Science Journal. 88:691-695
The rhythmic locomotor behavior of flies and mice provides a phenotype for the identification of clock genes, and the underlying molecular mechanism is well studied. However, interestingly, when examining locomotor rhythm in the wild, several key lab
Autor:
Shuichi, Ito, Shuho, Hori, Makiko, Hirose, Mari, Iwahara, Azusa, Yatsushiro, Atsushi, Matsumoto, Masayuki, Tanaka, Chinobu, Okamoto, Ken-Ichi, Yayou, Tsuyoshi, Shimmura
Publikováno v:
Animal science journal = Nihon chikusan Gakkaiho. 88(4)
The rhythmic locomotor behavior of flies and mice provides a phenotype for the identification of clock genes, and the underlying molecular mechanism is well studied. However, interestingly, when examining locomotor rhythm in the wild, several key lab
Autor:
Toshiaki Utsumi, Makiko Hirose, Katsumasa Kuroi, Shin Ichi Hayashi, Shinichiro Horiguchi, Nobuhiro Harada, Shigehira Saji, Naoko Honma
Publikováno v:
Cancer Science. 102:1848-1854
Estrogens play an important role in the pathobiology of breast cancer. In postmenopausal women, peripheral synthesis of estrogens from adrenal/ovarian androgens, dehydroepiandrosterone (DHEA) or androstenedione (Adione), by estrogen-metabolizing enzy
Autor:
Mitsuo Satoh, Eiji Suzuki, Makiko Hirose, Yukimasa Shiotsu, Masahide Kondo, Masakazu Toi, Shigeru Iida, Kenya Shitara, Mariko Muta, Rinpei Niwa, Shigehira Saji
Publikováno v:
Clinical Cancer Research. 13:1875-1882
Purpose: Removal of fucose residues from the oligosaccharides of human antibody is a powerful approach to enhance antibody-dependent cellular cytotoxicity (ADCC), a potential important antitumor mechanism of therapeutic antibodies. To provide clinica
Publikováno v:
Cancer chemotherapy and pharmacology. 56
Ever since the estrogen receptor (ER) beta was discovered in 1996, we have been trying to determine its value as a prognostic and/or predictive factor in breast cancer and its potential as a novel target for pharmacological intervention. Recent progr
Publikováno v:
Breast cancer (Tokyo, Japan). 11(2)
Enhancement of the therapeutic effect of conventional drugs is currently an active treatment strategy for breast cancer, as shown in the clinical application of trastuzumab with chemotherapeutic agents, which prolonged survival even for metastatic di
Autor:
Toshiya Funabashi, Kumiko Suyama, Makiko Hirose, Fukuko Kimura, Tsuguo Uemura, Fumiki Hirahara
Publikováno v:
Neuroendocrinology. 73(3)
Although it has been assumed that synchronized firing of gonadotropin-releasing hormone (GnRH) neurons is necessary for pulsatile GnRH secretion, there is no clear evidence for this. In the present study we simultaneously recorded spontaneous action
P4-01-20: Specific Anti-Proliferative Profile of Endoxifen for MCF-7 Cell Compared to 4-OH Tamoxifen
Publikováno v:
Cancer Research. 71:P4-01
Background: Endoxifen and 4-hydroxy tamoxifen are both active metabolites of tamoxifen and exert anti-tumor activity for ER+ breast cancer. However, only small numbers of paper reported biological profile of endoxifen. Methods: Cells were incubated w
Autor:
Makiko Hirose, Toshinari Ymashita, Mariko Muta, Susumu Sekine, Tomoyuki Aruga, Dai Kitagawa, Kazumi Horiguchi, Noriko Suzuki, Katsumasa Kuroi, Eiji Suzuki
Publikováno v:
Cancer Research. 70:5304-5304
Previously, we reported that serum from stage IV breast cancer patients diminished the cytotoxic activity of lymphokine activated killer cells (LAKs) (Abstract #4639 AACR in 2008). Thus, we next tested what the critical role for the inhibitory effect
Autor:
Naoko Honma, Shigehira Saji, Makiko Hirose, Shin-ichiro Horiguchi, Katsumasa Kuroi, Shin-ichi Hayashi, Toshiaki Utsumi, Nobuhiro Harada
Publikováno v:
Cancer Science; Oct2011, Vol. 102 Issue 10, p1848-1854, 7p, 2 Diagrams, 5 Graphs