Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Makiko HAYASHI"'
Autor:
Makiko Hayashi, Hiroaki Nakano
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Sea slugs of the family Chromodorididae (Nudibranchia, Gastropoda, Mollusca) have garnered attention by researchers and hobbyists alike for their bright and variable color patterns. However, the chromodorid life cycle has yet to be fully elu
Externí odkaz:
https://doaj.org/article/50610d82b6694aa3a866e28bc8f0716f
Autor:
Dimitris Karagiannis, Warren Wu, Albert Li, Makiko Hayashi, Xiao Chen, Michaela Yip, Vaibhav Mangipudy, Xinjing Xu, Francisco J. Sánchez-Rivera, Yadira M. Soto-Feliciano, Jiangbin Ye, Thales Papagiannakopoulos, Chao Lu
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113629- (2024)
Summary: The interplay between metabolism and chromatin signaling is implicated in cancer progression. However, whether and how metabolic reprogramming in tumors generates chromatin vulnerabilities remain unclear. Lung adenocarcinoma (LUAD) tumors fr
Externí odkaz:
https://doaj.org/article/84edbc8d07a24ae2ad1662e369769cc7
Autor:
Anastasia-Maria Zavitsanou, Ray Pillai, Yuan Hao, Warren L. Wu, Eric Bartnicki, Triantafyllia Karakousi, Sahith Rajalingam, Alberto Herrera, Angeliki Karatza, Ali Rashidfarrokhi, Sabrina Solis, Metamia Ciampricotti, Anna H. Yeaton, Ellie Ivanova, Corrin A. Wohlhieter, Terkild B. Buus, Makiko Hayashi, Burcu Karadal-Ferrena, Harvey I. Pass, John T. Poirier, Charles M. Rudin, Kwok-Kin Wong, Andre L. Moreira, Kamal M. Khanna, Aristotelis Tsirigos, Thales Papagiannakopoulos, Sergei B. Koralov
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113295- (2023)
Summary: Lung cancer treatment has benefited greatly through advancements in immunotherapies. However, immunotherapy often fails in patients with specific mutations like KEAP1, which are frequently found in lung adenocarcinoma. We established an anti
Externí odkaz:
https://doaj.org/article/240bdf74cb4547dea3fb1640afd7bcf5
Autor:
Saki Hirakata, MD, Hiroki Aoki, MD, PhD, Satoko Ohno-Urabe, MD, PhD, Michihide Nishihara, MD, PhD, Aya Furusho, MD, PhD, Norifumi Nishida, MD, Sohei Ito, MD, Makiko Hayashi, MD, Hideo Yasukawa, MD, PhD, Tsutomu Imaizumi, MD, PhD, Sinichi Hiromatsu, MD, PhD, Hiroyuki Tanaka, MD, PhD, Yoshihiro Fukumoto, MD, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 5, Iss 2, Pp 126-144 (2020)
Summary: Aortic dissection (AD) is the acute destruction of aortic wall and is reportedly induced by inflammatory response. Here we investigated the role of smooth muscle Socs3 (a negative regulator of Janus kinases/signal transducer and activator of
Externí odkaz:
https://doaj.org/article/83a8bf407ee34e8189a3a5b7ac49083d
Publikováno v:
IATSS Research, Vol 42, Iss 4, Pp 163-170 (2018)
This article provides the background to the special issue by reviewing the status of traffic problems in South East Asian countries, and in particular, the case of Cambodia. The “Make Roads Safe” report by the Commission for Global Road Safety (2
Externí odkaz:
https://doaj.org/article/f69dd68c3fb64b528d00e8fb260881b5
Autor:
Sohei Ito, Yohei Hashimoto, Ryohei Majima, Eichi Nakao, Hiroki Aoki, Michihide Nishihara, Satoko Ohno-Urabe, Aya Furusho, Saki Hirakata, Norifumi Nishida, Makiko Hayashi, Koichiro Kuwahara, Yoshihiro Fukumoto
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0229888 (2020)
Aortic dissection (AD) is a major cause of acute aortic syndrome with high mortality due to the destruction of aortic walls. Although recent studies indicate the critical role of inflammation in the disease mechanism of AD, it is unclear how inflamma
Externí odkaz:
https://doaj.org/article/5fa6f76b2ac84e608e3e7b1cff7720d9
Autor:
Eri H. Kobayashi, Takafumi Suzuki, Ryo Funayama, Takeshi Nagashima, Makiko Hayashi, Hiroki Sekine, Nobuyuki Tanaka, Takashi Moriguchi, Hozumi Motohashi, Keiko Nakayama, Masayuki Yamamoto
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Nrf2 is a transcriptional activator of oxidative stress response genes. Here the authors show that Nrf2 binds to promoters of proinflammatory genes and interferes with their transcriptional upregulation in LPS-stimulated macrophages independently of
Externí odkaz:
https://doaj.org/article/64f68c1a2df449c4a3c17e7079f6efb6
Autor:
Makiko Hayashi-Hori, Hiroki Aoki, Miho Matsukuma, Ryohei Majima, Yohei Hashimoto, Sohei Ito, Saki Hirakata, Norifumi Nishida, Aya Furusho, Satoko Ohno-Urabe, Yoshihiro Fukumoto
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3341 (2020)
Aortic dissection (AD) is a serious clinical condition that is unpredictable and frequently results in fatal outcome. Although rapamycin, an inhibitor of mechanistic target of rapamycin (mTOR), has been reported to be effective in preventing aortopat
Externí odkaz:
https://doaj.org/article/ad4187bc3a994edab492a236b4532a23
Autor:
Aya Furusho, Hiroki Aoki, Satoko Ohno‐Urabe, Michihide Nishihara, Saki Hirakata, Norifumi Nishida, Sohei Ito, Makiko Hayashi, Tsutomu Imaizumi, Shinichi Hiromatsu, Hidetoshi Akashi, Hiroyuki Tanaka, Yoshihiro Fukumoto
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 6 (2018)
BackgroundAbdominal aortic aneurysm (AAA) is a potentially life‐threatening disease that is common in older individuals. Currently, therapeutic options are limited to surgical interventions. Although it has long been known that AAA tissue is enrich
Externí odkaz:
https://doaj.org/article/9492db002dcb45b3a1cfd72148deaa27
Autor:
Satoko Ohno‐Urabe, Hiroki Aoki, Michihide Nishihara, Aya Furusho, Saki Hirakata, Norifumi Nishida, Sohei Ito, Makiko Hayashi, Hideo Yasukawa, Tsutomu Imaizumi, Hidetoshi Akashi, Hiroyuki Tanaka, Yoshihiro Fukumoto
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 2 (2018)
BackgroundAortic dissection (AD) is a life‐threatening medical emergency caused by the abrupt destruction of the intimomedial layer of the aortic walls. Given that previous studies have reported the involvement of proinflammatory cytokine interleuk
Externí odkaz:
https://doaj.org/article/cd499ab5c5b544cfb1f158a739decd87