Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Makiko Fukaya"'
Autor:
Diane Delaroche, E C Vanzela, Fernanda Ortis, Henrik B. Mortensen, Lotte B Nielsen, Alessandra K Cardozo, Joachim Størling, Geert van Loo, Leen Catrysse, Makiko Fukaya, Rudi Beyaert, Flemming Pociot, Marie Louise Max M.L. Andersen, Caroline Brorsson, Kira Meyerovich
Publikováno v:
Molecular Endocrinology. 30:48-61
Activation of the transcription factor nuclear factor kappa B (NFkB) contributes to β-cell death in type 1 diabetes (T1D). Genome-wide association studies have identified the gene TNF-induced protein 3 (TNFAIP3), encoding for the zinc finger protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::debff7b766cdfe4ae3f3b9d6495bfcb8
https://doi.org/10.1210/me.2015-1176
https://doi.org/10.1210/me.2015-1176
Autor:
Makiko Fukaya, Natalia Moretti Violato, Decio L. Eizirik, Violette Dirix, Alessandra K Cardozo, Lorella Marselli, Andreas Strasser, Nathalie Pachera, Kira Meyerovich, Piero Marchetti
Publikováno v:
Diabetes (New York, N.Y.), 66 (9
Diabetes
Diabetes
Induction of endoplasmic reticulum stress and activation of the intrinsic apoptotic pathway is widely believed to contribute to β-cell death in type 1 diabetes (T1D). MCL-1 is an anti-apoptotic member of the BCL-2 protein family, whose depletion cau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814fca50070e5f39ca94c803ba7e0e8a
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/254360
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/254360
Autor:
Eiji Takeda, Kikuko Amo, Yutaka Taketani, Hidekazu Arai, Takashi Uebanso, Megumi Koganei, Hirokazu Ohminami, Kazusa Sato, Makiko Fukaya, Hisami Yamanaka-Okumura, Hironori Yamamoto, Hajime Sasaki
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
A dietary combination of sucrose and linoleic acid strongly contributes to the development of metabolic disorders in Zucker fatty rats. However, the underlying mechanisms of the metabolic disorders are poorly understood. We hypothesized that the meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e678cd6df5d789c61a9b023152a92da2
https://doi.org/10.3164/jcbn.14-11
https://doi.org/10.3164/jcbn.14-11
Autor:
Shohei Shinozaki, Shingo Yasuhara, Yuji Fukushima, Makiko Fukaya, Masao Kaneki, Nobuyuki Shimizu, J. A. Jeevendra Martyn, Kyungho Chang, Mayu Habiro
Publikováno v:
Metabolism. 62:341-346
Recent studies suggest that activation of glycogen synthase kinase (GSK)-3β may be involved in burn injury-induced metabolic derangements and protein breakdown in skeletal muscle. However, the mechanism for GSK-3β activation after burn injury is un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8410cd9411e19d50d2754d72a85d2e2b
https://doi.org/10.1016/j.metabol.2012.08.010
https://doi.org/10.1016/j.metabol.2012.08.010
Autor:
Ji Mao, Tadahiro Kitamura, Makiko Fukaya, Toshihiro Tanioka, Masao Kaneki, Shohei Shinozaki, Yoshiaki Tamura, Nobuyuki Shimizu, Minhye Kim
Publikováno v:
Journal of Biological Chemistry. 286:29388-29396
Insulin receptor substrate-2 (IRS-2) plays a critical role in the survival and function of pancreatic β-cells. Gene disruption of IRS-2 results in failure of the β-cell compensatory mechanism and diabetes. Nonetheless, the regulation of IRS-2 prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e053521fbaa8b86f65078189146f72af
https://doi.org/10.1074/jbc.m110.192732
https://doi.org/10.1074/jbc.m110.192732
Autor:
Kikuko Amo, Hajime Sasaki, Eiji Takeda, Yutaka Taketani, Hidekazu Arai, Hironori Yamamoto, Takashi Uebanso, Megumi Koganei, Makiko Fukaya
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
Xylitol is widely used as a sweetener in foods and medications. Xylitol ingestion causes a small blood glucose rise, and it is commonly used as an alternative to high-energy supplements in diabetics. In previous studies, a xylitol metabolite, xylulos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3533efb36c25de9f467772a2536bbd
http://europepmc.org/articles/PMC3128359
http://europepmc.org/articles/PMC3128359
Autor:
Hisami Okumura, Eiji Takeda, Toshio Doi, Akira Mizuno, Nagakatsu Harada, Yutaka Taketani, Naomi Awane, Hironori Yamamoto, Makiko Fukaya, Hidekazu Arai, Akihiko Kawaura, Masae Sakuma
Publikováno v:
The Journal of Medical Investigation. 57:54-61
A number of recent publications have reported an increased frequency prevalence of glucose intolerance with hyperinsulinemia in liver cirrhosis. The aim of this work was to detect, in CCl(4)-induced liver cirrhosis rat, the presence and starting poin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94dc6d8699570c57afbe3564abacd9d
https://doi.org/10.2152/jmi.57.54
https://doi.org/10.2152/jmi.57.54
Autor:
Makiko Fukaya, Takashi Uebanso, Tadatoshi Sato, Yuichiro Takei, Eiji Takeda, Yutaka Taketani, Naoki Sawada, Nagakatsu Harada, Hironori Yamamoto, Hidekazu Arai, Kazusa Sato, Kikuko Amo
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 297:E76-E84
The mechanism by which replacement of some dietary carbohydrates with protein during weight loss favors lipid metabolism remains obscure. In this study, we investigated the effect of an energy-restricted, high-protein/low-carbohydrate diet on lipid m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f795747cd6cdab4f14af89229c45546
https://doi.org/10.1152/ajpendo.00014.2009
https://doi.org/10.1152/ajpendo.00014.2009
Autor:
Yutaka Taketani, Makiko Fukaya, Eiji Takeda, Hidekazu Arai, Hajime Sasaki, Yui Miyazawa, Tadatoshi Sato, Takashi Uebanso, Kazusa Sato, Megumi Koganei, Hironori Yamamoto
Publikováno v:
The Journal of Medical Investigation. 55:183-195
We showed previously that 8-wk consumption of a diet containing palatinose (P, a slowly-absorbed sucrose analogue) and oleic acid (O) ameliorates but a diet containing sucrose (S) and linoleic acid (L) aggravates metabolic abnormalities in Zucker fat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::477c2d70921a0ff03aa79bef4c420e94
https://doi.org/10.2152/jmi.55.183
https://doi.org/10.2152/jmi.55.183
Autor:
Makiko Fukaya, Hidekazu Arai, Yutaka Taketani, Toshio Doi, Akira Mizuno, Eiji Takeda, Hironori Yamamoto, Megumi Koganei, Hajime Sasaki, Tadatoshi Sato, Kazusa Sato
Publikováno v:
The Journal of Nutrition. 137:1908-1915
Excessive dietary intake of carbohydrates and fats has been linked to the development of obesity. However, the mechanism by which these dietary factors interact to bring about metabolic changes has not been elucidated. We examined the combined effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::232c7d243471850a6082f7a42552e0e9
https://doi.org/10.1093/jn/137.8.1908
https://doi.org/10.1093/jn/137.8.1908