Výsledky vyhledávání - "Makiko Fliss"

Mitochondrial mutations in early stage prostate cancer and bodily fluids

Autor: Carlos Lopes, Shuji Nomoto, Carmen Jerónimo, David Sidransky, Rui Henrique, Otavia L. Caballero, Makiko Fliss, Jorge Oliveira, Henning Usadel, Graça Varzim

Publikováno v: Oncogene. 20:5195-5198

We recently demonstrated the existence of specific patterns of somatic mitochondrial DNA (mtDNA) mutations in several cancers. Here we sought to identify the presence of mtDNA mutations in prostate cancer and their paired PIN lesions. The D-loop regi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a709da7de6e705507a9625def340aad4
https://doi.org/10.1038/sj.onc.1204646

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Expression Cloning and Characterization of PREB (Prolactin Regulatory Element Binding), a Novel WD Motif DNA-Binding Protein with a Capacity to Regulate Prolactin Promoter Activity

Autor: Carter Bancroft, Patricia M. Hinkle, Makiko Fliss

Publikováno v: Molecular Endocrinology. 13:644-657

Previous studies have implied that a transcription factor(s) other than Pit-1 is involved in homeostatic regulation of PRL promoter activity via Pit-1-binding elements. One such element, 1P, was employed to clone from a rat pituitary cDNA expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8acee4599be23af788fcfcd995170bcb
https://doi.org/10.1210/mend.13.4.0260

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Making DNA Add

Autor: Frank Guarnieri, Carter Bancroft, Makiko Fliss

Publikováno v: Science. 273:220-223

Recent studies have demonstrated the feasibility of using DNA-based experiments to compute solutions to combinatorial problems. However, a prerequisite for designing a computer useful in a wide range of applications is the ability to perform mathemat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd612ff729b8fcf511b1f5922947e59c
https://doi.org/10.1126/science.273.5272.220

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Facile detection of mitochondrial DNA mutations in tumors and bodily fluids

Autor: Scott M. Eleff, David Sidransky, Jin Jen, Li Wu, Otavia L. Caballero, Henning Usadel, Martin Buta, Makiko Fliss

Publikováno v: Science (New York, N.Y.). 287(5460)

Examination of human bladder, head and neck, and lung primary tumors revealed a high frequency of mitochondrial DNA (mtDNA) mutations. The majority of these somatic mutations were homoplasmic in nature, indicating that the mutant mtDNA became dominan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2e2d88d64223fa26e5e7b71769483aa
https://pubmed.ncbi.nlm.nih.gov/10720328

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