Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Makiko Endoh"'
Publikováno v:
Journal of Pharmacobio-Dynamics. 13:179-185
To predict quantitatively drug interaction kinetics from the single-drug clearance studies, we examined the effect of iodopyracet (IOD) on sulfamethizole (SMZ) excretion in rabbits. Even though the decline of systemic IOD plasma concentration was lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3d6153072cbc21e79d580682bbc895b
https://doi.org/10.1248/bpb1978.13.179
https://doi.org/10.1248/bpb1978.13.179
Kinetic studies on drug disposition in rabbits. I. Renal excretion of iodopyracet and sulfamethizole
Autor:
Makiko Endoh, Kazunori Katayama, Tamotsu Koizumi, Toshihiko Kawabe, Hiroyuki Ohtani, Masawo Kakemi, Hiromoto Mizuno
Publikováno v:
Journal of pharmacobio-dynamics. 13(2)
In order to quantify the renal handling of iodopyracet (IOD) and sulfamethizole (SMZ), single-drug clearance studies in rabbits were performed under quasi-steady state conditions with stepwise increasing the infusion rate of IOD or SMZ. Although conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9992ae57b30c4afc6d3cbdb02d77cfad
https://pubmed.ncbi.nlm.nih.gov/2384854
https://pubmed.ncbi.nlm.nih.gov/2384854
Autor:
Masahiro Suzuki, Makiko Endoh, Tamotsu Koizumi, Kazunori Katayama, Toyoshi Kuroda, Masawo Kakemi
Publikováno v:
Journal of Pharmacobio-Dynamics. 8:711-717
After administration of captopril, a decrease in mean arterial blood pressure was observed in low sodium rats which were used as animal models of hyper-renin-active pathema. In normal rats, however, this marked decrease in blood pressure was not obse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::877a90bdb36a8e1c68089db61f4d335e
https://doi.org/10.1248/bpb1978.8.711
https://doi.org/10.1248/bpb1978.8.711
Publikováno v:
Journal of Pharmacobio-Dynamics. 12:1-9
Pressor response to exogenous angiotensins was investigated in rats. Two-kidney Goldblatt hypertensive rats (GHR) and sodium-deficient normotensive rats (SDR), as well as normal rats, (NR) were used. Various amounts of angiotensin I (Ang I) or angiot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb6ee878c54b33ffa8278757b6471f4
https://doi.org/10.1248/bpb1978.12.1
https://doi.org/10.1248/bpb1978.12.1
Publikováno v:
Journal of Pharmacobio-Dynamics. 11:314-323
The diuretic effect of piretanide, one of the loop diuretics, was investigated in three different hydrated conditions, namely well hydrated condition (treatment I), progressive hydropenic condition (treatment II) and complete hydropenic condition (tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed73148ca3538204a84cbb6ce6e4156
https://doi.org/10.1248/bpb1978.11.314
https://doi.org/10.1248/bpb1978.11.314
Publikováno v:
Journal of pharmacobio-dynamics. 11(2)
In order to clarify the effect of piretanide in the nephrons, pharmacokinetics and pharmacodynamics of piretanide were studied under a hydropenic condition in the rabbit. The hydropenic condition was developed by a simultaneous infusion of an antidiu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e2554151abe0bd44cf44168d608d24
https://pubmed.ncbi.nlm.nih.gov/3379569
https://pubmed.ncbi.nlm.nih.gov/3379569
Autor:
Masawo Kakemi, Tomomi Hatanaka, Makiko Endoh, Tamotsu Koizumi, Shinji Sato, Kooichi Ohshima, Kazunori Katayama
Publikováno v:
Journal of pharmacobio-dynamics. 9(12)
Using the basic equations for heat balance, a compartment model was constructed to simulate the physiological responses to heat and cold in rats. The model predicted steady-state situations of rectal temperature, skin temperature (pelt and tail), met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6368e91b2a2b63dd2abd2414bbb6a6
https://pubmed.ncbi.nlm.nih.gov/3572719
https://pubmed.ncbi.nlm.nih.gov/3572719
Publikováno v:
Journal of pharmacobio-dynamics. 10(8)
The pharmacokinetics and pharmacodynamics of piretanide in rabbits were investigated. After intravenous administration, the plasma concentrations and the urinary excretion rates of piretanide, as well as the pharmacologic effects, were measured under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f1b783f56f4504e7d71cf3674d254f
https://pubmed.ncbi.nlm.nih.gov/3694429
https://pubmed.ncbi.nlm.nih.gov/3694429
Publikováno v:
Chemicalpharmaceutical bulletin. 37(7)
Permeation of sulfisoxazole (SIX) across the excised rat skin were studied using two chamber cell with four electrodes, under three successive experimental conditions: without current for 3 h (treatment I), with current for 4 h (treatment II) and wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db2f337371e6b1ff984f1aa61108dfa6
https://pubmed.ncbi.nlm.nih.gov/2805167
https://pubmed.ncbi.nlm.nih.gov/2805167
Publikováno v:
Journal of pharmacobio-dynamics. 6(2)
The purpose of this investigation is to elucidate the relationship between the time course of pharmacologic effects and drug disposition after administration of metformin, an oral antidiabetic drug of biguanides. Alloxan diabetic rats and normal rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58be028c000205944f9c633a46f9745b
https://pubmed.ncbi.nlm.nih.gov/6864442
https://pubmed.ncbi.nlm.nih.gov/6864442