Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Maki Sugaya"'
Autor:
Melvin Pan, Christiane Zorbas, Maki Sugaya, Kensuke Ishiguro, Miki Kato, Miyuki Nishida, Hai-Feng Zhang, Marco M. Candeias, Akimitsu Okamoto, Takamasa Ishikawa, Tomoyoshi Soga, Hiroyuki Aburatani, Juro Sakai, Yoshihiro Matsumura, Tsutomu Suzuki, Christopher G. Proud, Denis L. J. Lafontaine, Tsuyoshi Osawa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Small molecules that target RNA Polymerase I inhibit ribosome biogenesis to activate p53 through the nucleolar surveillance response pathway. Here, the authors show that p53 induction by ribosome stress is dependent on extracellular glutamine availab
Externí odkaz:
https://doaj.org/article/5a2c48021da748188909409721466a55
Autor:
Manami Katoh, Seitaro Nomura, Shintaro Yamada, Masamichi Ito, Hiroki Hayashi, Mikako Katagiri, Tuolisi Heryed, Takayuki Fujiwara, Norifumi Takeda, Miyuki Nishida, Maki Sugaya, Miki Kato, Tsuyoshi Osawa, Hiroyuki Abe, Yoshitaka Sakurai, Toshiyuki Ko, Kanna Fujita, Bo Zhang, Satoshi Hatsuse, Takanobu Yamada
Publikováno v:
Circulation; 7/30/2024, Vol. 150 Issue 5, p374-389, 16p
Autor:
Akihiro Kitagawa, Tsuyoshi Osawa, Miwa Noda, Yuta Kobayashi, Sho Aki, Yusuke Nakano, Tomoko Saito, Dai Shimizu, Hisateru Komatsu, Maki Sugaya, Junichi Takahashi, Keisuke Kosai, Seiichiro Takao, Yushi Motomura, Kuniaki Sato, Qingjiang Hu, Atsushi Fujii, Hiroaki Wakiyama, Taro Tobo, Hiroki Uchida, Keishi Sugimachi, Kohei Shibata, Tohru Utsunomiya, Shogo Kobayashi, Hideshi Ishii, Takanori Hasegawa, Takaaki Masuda, Yusuke Matsui, Atsushi Niida, Tomoyoshi Soga, Yutaka Suzuki, Satoru Miyano, Hiroyuki Aburatani, Yuichiro Doki, Hidetoshi Eguchi, Masaki Mori, Keiichi I. Nakayama, Teppei Shimamura, Tatsuhiro Shibata, Koshi Mimori
Publikováno v:
British Journal of Cancer.
Background Driver alterations may represent novel candidates for driver gene-guided therapy; however, intrahepatic cholangiocarcinoma (ICC) with multiple genomic aberrations makes them intractable. Therefore, the pathogenesis and metabolic changes of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc5132a5312f63c97f15f2777fac3609
https://doi.org/10.1038/s41416-023-02256-4
https://doi.org/10.1038/s41416-023-02256-4
Autor:
Sana Hibino, Shotaro Eto, Sho Hangai, Keiko Endo, Sanae Ashitani, Maki Sugaya, Tsuyoshi Osawa, Tomoyoshi Soga, Tadatsugu Taniguchi, Hideyuki Yanai
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 6/13/2023, Vol. 120 Issue 24, p1-10, 31p
Autor:
Melvin Pan, Christiane Zorbas, Maki Sugaya, Kensuke Ishiguro, Miki Kato, Miyuki Nishida, Hai-Feng Zhang, Marco M Candeias, Akimitsu Okamoto, Takamasa Ishikawa, Tomoyoshi Soga, Hiroyuki Aburatani, Juro Sakai, Yoshihiro Matsumura, Tsutomu Suzuki, Christopher G. Proud, Denis L. J. Lafontaine, Tsuyoshi Osawa
SummaryRibosome biogenesis involves the processing of precursor ribosomal RNAs (pre-rRNAs) and sequential assembly with ribosomal proteins. Here we report that nutrient deprivation severely impairs pre-rRNA processing and leads to the accumulation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e4870a7eb9451f853334ddf263914a1
https://doi.org/10.1101/2021.12.03.471189
https://doi.org/10.1101/2021.12.03.471189
Autor:
Melvin Pan, Christiane Zorbas, Maki Sugaya, Kensuke Ishiguro, Miki Kato, Miyuki Nishida, Hai-Feng Zhang, Marco M. Candeias, Akimitsu Okamoto, Takamasa Ishikawa, Tomoyoshi Soga, Hiroyuki Aburatani, Juro Sakai, Yoshihiro Matsumura, Tsutomu Suzuki, Christopher G. Proud, Denis L. J. Lafontaine, Tsuyoshi Osawa
Publikováno v:
Nature communications. 13(1)
Ribosome biogenesis is an energetically expensive program that is dictated by nutrient availability. Here we report that nutrient deprivation severely impairs precursor ribosomal RNA (pre-rRNA) processing and leads to the accumulation of unprocessed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb7b5cdc3a2411f369f783f77b97c8c
https://pubmed.ncbi.nlm.nih.gov/35764642
https://pubmed.ncbi.nlm.nih.gov/35764642
Autor:
Kyojiro Kawakami, Kosuke Mizutani, Kengo Horie, Maki Sugaya, Yasunori Fujita, Koji Kameyama, Masafumi Ito, Takashi Deguchi
Publikováno v:
Biochemical and biophysical research communications. 492(3)
Exosomes or microvesicles that are secreted from cells are considered to play important roles in tumor microenvironment. Carbonic anhydrase 9 (CA9), which is induced by hypoxia-inducible factor 1 (HIF1) in response to hypoxia, is overexpressed in man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f155c0021a87c119103d14eb21e53aab
https://pubmed.ncbi.nlm.nih.gov/28851650
https://pubmed.ncbi.nlm.nih.gov/28851650
Autor:
Mitsuru Higuchi, Yu Taniguchi, Yoshinori Fujiwara, Hiroyuki Suzuki, Nobuyoshi Hirose, Yasumichi Arai, Masaaki Muramatsu, Masashi Tanaka, Motoji Sawabe, Shuichi Obuchi, Tomio Arai, Motonaga Kojima, Hisashi Kawai, Hirohiko Hirano, Hiroshi Shimokata, Noriko Sato, Yoshiji Yamada, Kumpei Tanisawa, Shoji Shinkai, Seijiro Mori, Kazushige Ihara, Maki Sugaya
Publikováno v:
The journals of gerontology. Series A, Biological sciences and medical sciences. 73(5)
Growth hormone (GH)/insulin-like growth factor-1 (IGF-1)/insulin signaling is one of the most plausible biological pathways regulating aging and longevity. Previous studies have demonstrated that several single nucleotide polymorphisms (SNPs) in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2ff2a80fb740b35ea4d82f37b377be
https://pubmed.ncbi.nlm.nih.gov/28958036
https://pubmed.ncbi.nlm.nih.gov/28958036
Autor:
Masashi Tanaka, Ikuroh Ohsawa, Maki Sugaya, Masaya Ishigaki, Masumi Iketani, Seisuke Hattori, Mayumi Takahashi
Publikováno v:
Mitochondrion. 28
We applied stimulated emission depletion (STED) imaging with subdiffraction resolution to submitochondrial structures in mitochondria. Their shapes depend on both a cell's type and its physiological state. Staining with a cationic fluorescent dye, te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290519b35a5e46c66fba0d991ca61735
https://pubmed.ncbi.nlm.nih.gov/27090168
https://pubmed.ncbi.nlm.nih.gov/27090168
Publikováno v:
Biochemical Genetics. 48:816-821
Glutathione is an antioxidant that helps protect cells from reactive oxygen species, such as free radicals and peroxides (Meister 1988; Pompella et al. 2003). Synthesized from the amino acids cysteine, glutamic acid, and glycine, it contains a peptid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ad5d177f5b55ef050582d173fba293
https://doi.org/10.1007/s10528-010-9362-z
https://doi.org/10.1007/s10528-010-9362-z