Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Maki Saitoh"'
Autor:
James G. Davis, Deanna Stevens, Dudley W. Lamming, Adam B. Salmon, Pekka Katajisto, Maki Saitoh, Marcus D. Goncalves, Rexford S. Ahima, David A. Guertin, Joseph A. Baur, Arlan Richardson, Lan Ye, David M. Sabatini
Publikováno v:
Science. 335:1638-1643
Dissecting Rapamycin Responses Long-term treatment of mice and other organisms with the drug rapamycin extends life span. But, at the same time, the drug disrupts metabolic regulation and the action of the hormone insulin. Lamming et al. (p. 1638 ; s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02f27b77711b8cba6875e74d1ed3e6a
https://doi.org/10.1126/science.1215135
https://doi.org/10.1126/science.1215135
Autor:
Maki Saitoh, Deanna Stevens, David J. Mullholland, Katherine Crosby, Joon-Ho Sheen, Hong Wu, Mark A. Magnuson, Stephanie Kinkel, David M. Sabatini, David A. Guertin
Publikováno v:
Cancer Cell. 15(2):148-159
SummarymTOR complex 2 (mTORC2) contains the mammalian target of rapamycin (mTOR) kinase and the Rictor regulatory protein and phosphorylates Akt. Whether this function of mTORC2 is critical for cancer progression is unknown. Here, we show that transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f0479078e24070846177b099cea7cc
Publikováno v:
Pathology International. 55:372-375
Primary vaginal adenocarcinomas are rare neoplasms. Herein is reported a case of primary vaginal mucinous adenocarcinoma with an interesting mucin profile, presumably arising from a lesion of adenosis in a patient without in utero exposure to diethyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d3561cf52a828abb81468e7580d42c
https://doi.org/10.1111/j.1440-1827.2005.01839.x
https://doi.org/10.1111/j.1440-1827.2005.01839.x
Autor:
Chika Ohshima, Masahide Ohmichi, Hirohisa Kurachi, Akira Ohishi, Kazuhiro Takahashi, Botao Du, Maki Saitoh, Tsuyoshi Ohta, Masakazu Doshida, Naohiro Tezuka, Akiko Mori-Abe, Jun Kawagoe, Hideki Igarashi, Toshifumi Takahashi
Publikováno v:
Journal of Endocrinology. 183:605-615
Although estrogen is known to protect against β-amyloid (Aβ)-induced neurotoxicity, the mechanisms responsible for this effect are only beginning to be elucidated. In addition, the effect of raloxifene on Aβ-induced neuro-toxicity remains unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::691125ba88f09588fb85466f3f9fae79
https://doi.org/10.1677/joe.1.05775
https://doi.org/10.1677/joe.1.05775
Autor:
Satoru Kyo, Seiji Mabuchi, Jun Kawagoe, Chika Ohshima, Hirohisa Kurachi, Maki Saitoh, Masahide Ohmichi, Masaki Inoue, Kazuhiro Takahashi, Akiko Kimura, Hideki Igarashi, Toshifumi Takahashi, Tsuyoshi Ohta, Akiko Mori-Abe, Botao Du
Publikováno v:
Journal of Biological Chemistry. 278:43363-43372
The mechanism by which raloxifene acts in the chemoprevention of breast cancer remains unclear. Because telomerase activity is involved in estrogen-induced carcinogenesis, we examined the effect of raloxifene on estrogen-induced up-regulation of telo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df3e2b11ba83d5163d671c96e7cc3ff
https://doi.org/10.1074/jbc.m304363200
https://doi.org/10.1074/jbc.m304363200
Publikováno v:
Journal of Obstetrics and Gynaecology Research. 31:576-578
We report the case of a 51-year-old Japanese woman with a giant (50.75-kg) ovarian tumor. The histopathologic diagnosis was mucinous cystadenocarcinoma. After surgery, the patient was intubated and connected to a respirator for 8 days. Thereafter, sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e58d1e7fac227b4aa93b9b026024de48
https://doi.org/10.1111/j.1447-0756.2005.00340.x
https://doi.org/10.1111/j.1447-0756.2005.00340.x
Autor:
Ryosuke, Shigematsu, Rei, Nakanishi, Maki, Saitoh, Tomohiro, Okura, Masaki, Nakagaichi, Yoshio, Nakata, Tomoaki, Sakai, Yoichi, Nakamura, Mayumi, Kurimoto, Kiyoji, Tanaka
Publikováno v:
[Nihon koshu eisei zasshi] Japanese journal of public health. 58(1)
Square-Stepping Exercise (SSE), composed of movements similar to walking, involves varied movements in multiple directions and is performed on a thin mat (100 x 250 cm) that is partitioned into 40 squares (25 cm each). We introduced SSE to a group of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e949b9f821ccb14ef2eb0ecedde4f5de
https://pubmed.ncbi.nlm.nih.gov/21409820
https://pubmed.ncbi.nlm.nih.gov/21409820
Autor:
Tsuyoshi, Ohta, Masanori, Isobe, Toshifumi, Takahashi, Maki, Saitoh-Sekiguchi, Teiichi, Motoyama, Hirohisa, Kurachi
Publikováno v:
Anticancer research. 29(11)
To investigate the phosphatidylinositol 3-kinase (PI3K)-Akt and extracellular signal regulated protein kinase (ERK) activation by chemotherapy, and the relationship between the activation of them and patient outcomes. The effect of chemotherapy on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3052b21f9fcaaba8d39e2654ef94ada
https://pubmed.ncbi.nlm.nih.gov/20032415
https://pubmed.ncbi.nlm.nih.gov/20032415
Autor:
Maki, Saitoh-Sekiguchi, Kenji, Nakahara, Takanobu, Kojimahara, Tsuyoshi, Ohta, Jun, Kawagoe, Tsuyosi, Ohnuki, Tadashi, Hayasaka, Teiichi, Motoyama, Hirohisa, Kurachi
Publikováno v:
Anticancer research. 27(4C)
Small cell carcinoma of the ovary is a rare type of ovarian carcinoma with a very poor prognosis.We report here a case of a 55-year-old woman with small cell carcinoma of the left ovary. The patient underwent cytoreductive surgery with residual tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ebc108cc6c785654b59166d47eb7489
https://pubmed.ncbi.nlm.nih.gov/17695433
https://pubmed.ncbi.nlm.nih.gov/17695433
Autor:
Hirohisa Kurachi, Toshifumi Takahashi, Kazuhiro Takahashi, Botao Du, Tsuyoshi Ohta, Jun Kawagoe, Akiko Mori-Abe, Seiji Tsutsumi, Masakazu Doshida, Maki Saitoh-Sekiguchi, Masahide Ohmichi
Publikováno v:
The Journal of biological chemistry. 281(34)
Vascular endothelial senescence is involved in human atherosclerosis. Telomerase activity is known to be critical in cellular senescence and its level is modulated by regulation of telomerase catalytic subunit (telomerase reverse transcriptase (TERT)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b292bb1af4844c6a2f6bf5495cb33d
https://pubmed.ncbi.nlm.nih.gov/16798746
https://pubmed.ncbi.nlm.nih.gov/16798746