Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Maki Moritani"'
Publikováno v:
Journal of Diabetes Research, Vol 2021 (2021)
Background. Maturity-onset diabetes of the young (MODY) is commonly misdiagnosed as type 1 or type 2 diabetes. Common reasons for misdiagnosis are related to limitations in genetic testing. A precise molecular diagnosis is essential for the optimal t
Externí odkaz:
https://doaj.org/article/03829d726785418c91cc487afa340338
Publikováno v:
Journal of Diabetes Research, Vol 2021 (2021)
Background. Maturity-onset diabetes of the young (MODY) is commonly misdiagnosed as type 1 or type 2 diabetes. Common reasons for misdiagnosis are related to limitations in genetic testing. A precise molecular diagnosis is essential for the optimal t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7608fa992b094d76b1b909e2d479604b
https://doi.org/10.1155/2021/7216339
https://doi.org/10.1155/2021/7216339
Publikováno v:
Journal of Diabetes Research
Background Maturity-onset diabetes of the young (MODY) is commonly misdiagnosed as type 1 or type 2 diabetes. Common reasons for misdiagnosis are related to limitations in genetic testing. A precise molecular diagnosis is essential for the optimal tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7f3ba594f92a5e14374e0c61cd041e83
https://pubmed.ncbi.nlm.nih.gov/34746319
https://pubmed.ncbi.nlm.nih.gov/34746319
Autor:
Maki Moritani, Yukihiro Hasegawa, Masaki Takagi, Hiroyuki Shinohara, Kentaro Miyai, Hiroko Yagi, Ryojun Takeda, Ichiro Yokota
Publikováno v:
Clinical Pediatric Endocrinology
Permanent neonatal diabetes mellitus (PNDM) is a rare form of insulin-dependent diabetes mellitus that presents within the first 6 months after birth and may require lifelong insulin treatment. Approximately 40% of all PNDM cases are caused by activa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48efdfa0c6ccf2c90f057771632ffd54
https://doi.org/10.1297/cpe.24.191
https://doi.org/10.1297/cpe.24.191
Autor:
Nobuyuki Kikuchi, Maki Moritani, Reiko Horikawa, Aki Nishii, Ichiro Yokota, Tsutomu Ogata, Shigetaka Sugihara, Adolescent Diabetes (JSGIT)ª, Shin Amemiya, Tatsuhiko Urakami, Touru Kikuchi, Tomoyuki Kawamura
Publikováno v:
Journal of pediatric endocrinologymetabolism : JPEM. 29(9)
Monogenic mutations, such as those in the potassium inwardly-rectifying channel, subfamily J, member 11 (KCNJ11) and insulin (INS) genes, are identified in young patients with type 1B diabetes (non-autoimmune-mediated). We recently reported the resul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d58d3f4a1ae03fa7524ae36058054420
https://pubmed.ncbi.nlm.nih.gov/27398945
https://pubmed.ncbi.nlm.nih.gov/27398945
Autor:
Susumu Kitayama, Hiroshi Inoue, Mitsuo Itakura, Takao Suzuki, Shigeru Takeshita, Maki Moritani
Publikováno v:
Genes & Genetic Systems. 87:341-346
We have previously identified four significant quantitative trait loci (QTL) affecting plasma glucose concentrations on F(2) progeny of hypoinsulinemic diabetic Akita mice, heterozygous for the Ins2 gene Cys96Tyr mutation, and non-diabetic A/J mice,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c449092139e13b1aae7a5d670c021369
https://doi.org/10.1266/ggs.87.341
https://doi.org/10.1266/ggs.87.341
Autor:
Hiroshi Inoue, Maki Moritani, Takao Suzuki, Mitsuo Itakura, Shigeru Takeshita, Susumu Kitayama
Publikováno v:
Genes & Genetic Systems. 87:253-264
We have previously identified significant quantitative trait loci (QTL) Dbm1 (diabetic modifier QTL 1) on chromosome 6, affecting plasma glucose and insulin concentrations and body weight on F(2) progeny of hypoinsulinemic diabetic Akita mice, with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f70775bd09c52839bca8838b1489df1a
https://doi.org/10.1266/ggs.87.253
https://doi.org/10.1266/ggs.87.253
Publikováno v:
Endocrine Journal. 58:741-746
We examined children who were diagnosed with asymptomatic type 2 diabetes by school medical examinations to investigate the existence of glucokinase (GCK) gene defects in this group. Among 20 children diagnosed with asymptomatic type 2 diabetes by sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65c69dec99c658081751eef0e719682f
https://doi.org/10.1507/endocrj.k11e-062
https://doi.org/10.1507/endocrj.k11e-062
Autor:
Toshihito Tanahashi, Maki Moritani, Mitsuo Itakura, Naoto Nakamura, Tetsuro Ohmori, Katsuyuki Miyawaki, Kazue Tsugawa, Kiyoshi Kunika, Shusuke Numata, Hiroshi Inoue, Shu-ichi Ueno
Publikováno v:
Journal of Human Genetics. 53:972-982
Genetic variants of the transcription factor 7-like 2 (TCF7L2) gene affect the risk of type 2 diabetes in populations with multiple ethnic groups. However, a comprehensive survey of this gene has not been done for a Japanese population. Thus, we cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5584e10f2b9df8f475c1c0deb5b7ceab
https://doi.org/10.1007/s10038-008-0339-2
https://doi.org/10.1007/s10038-008-0339-2
Autor:
Kiyoshi Kunika, Hiroshi Inoue, Maki Moritani, Mitsuo Itakura, Parvaneh Keshavarz, Katsuyuki Miyawaki, Toshihito Tanahashi, Kuniko Mizuta, Aya Sato, Yukiko Sakamoto
Publikováno v:
Diabetes Research and Clinical Practice. 82:33-41
In an attempt to rectify the hyperglycemic state in obese insulin resistant db / db mice, a transgenic line was generated ( db / db-CDK4 R24C ) that expresses a constitutively active form of cyclin-dependent kinase 4 (CDK4/R24C) under the control of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38aa52aff5f7dee5d322675dc5f33f28
https://doi.org/10.1016/j.diabres.2008.06.014
https://doi.org/10.1016/j.diabres.2008.06.014