Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Maki MITSUHASHI"'
Publikováno v:
Kampo Medicine. 73:279-283
Autor:
Hiroko Fukushima, Maki Mitsuhashi, Hidefumi Miyagawa, Yuzo Fukushima, Ryosuke Fujita, Hiroshi Togi
Publikováno v:
Kampo Medicine. 71:224-227
Publikováno v:
Annals of Cancer Research and Therapy. 16:31-35
Publikováno v:
Journal of Leukocyte Biology. 76:322-332
Interleukin-12 (IL-12)-mediated immune responses are critical for the control of malignant development. Tumors can actively resist detrimental immunity of the host via many routes. Prostaglandin E2 (PGE2) is one of the major immune-suppressive factor
Publikováno v:
International Journal of Cancer. 110:570-578
Interleukin-12 (IL-12) has potent antitumor activities via natural killer cells and cytotoxic T lymphocytes. However, the molecular mechanisms whereby IL-12 induces tumoricidal activities are poorly understood. Here, we report the genome-wide analysi
Publikováno v:
The Journal of Immunology. 172:4111-4122
IL-12 is a major activator of tumor-killing NK cells and CTL. IFN-γ mediates most of the well-known immunological activities of IL-12. In this study, we report IFN-γ-independent activities induced by therapeutic application of rIL-12 in restricting
Autor:
Daisaburo Fujimoto, Hitoshi Nagata, Satoru Harumiya, Noboru Saito, Koichi Soyama, Tatsuhiro Hayashi, Chiaki Narumo, Maki Mitsuhashi, Shingo Kameoka
Publikováno v:
International Journal of Clinical Oncology. 6:215-220
Background. To prevent tumor metastasis, we administered the cell-binding domain of fibronectin, in combination with the angiogenesis inhibitor TNP-470, to mice with hepatic metastasis. We then assessed the prevention of tumor metastasis resulting fr
Autor:
Hitoshi Nagata, Maki Mitsuhashi, Noboru Saito, Shingo Kameoka, Daisaburo Fujimoto, Satoru Harumiya, Kyoichi Hamano, Tatsuhiro Hayashi
Publikováno v:
The Japanese Journal of Gastroenterological Surgery. 29:884-887
癌の浸潤・転移の過程での細胞接着分子の役割に着目し, マウス肝転移モデルにおいて細胞接着ドメイン投与を行い, 癌細胞との接着相互作用を制御することにより, 癌転移の抑制を検討
Publikováno v:
Annals of Cancer Research and Therapy. 3:97-101,69
Autor:
Hironari Shindo, Hideto Ohishi, Takayuki Shijo, Kan Asahina, Maki Mitsuhashi, Kyoichi Hamano, Shingo Kameoka, Ikkyo Kawa, Kiyotaka Nakajima, Michio Itabashi, Keiko Suzuki
Publikováno v:
The journal of the Japanese Practical Surgeon Society. 55:1545-1549
We recently encountered a patient having a small protuberant lesion in the rectum, who has been affected with ulcerative colitis of the total colitis type for 22 years. Early cancer was suspected, and surgery was performed. Pathologically, invasion t