Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Maki Iizuka"'
Autor:
Shunichi Takiguchi, Harumi Uto-Kondo, Makiko Yogo, Katsunori Ikewaki, Emi Yakushiji, Maki Iizuka, Kazuhiro Nakaya, Takafumi Nishida, Tomohiro Komatsu, Masatsune Ogura, Yoshio Terao, Makoto Sasaki, Makoto Ayaori
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Supplemental Digital Content is available in the text.
Objective— Reverse cholesterol transport (RCT) is a major mechanism by which HDL (high-density lipoprotein) protects against atherosclerosis. Endothelial lipase (EL) reportedly reduces HDL
Objective— Reverse cholesterol transport (RCT) is a major mechanism by which HDL (high-density lipoprotein) protects against atherosclerosis. Endothelial lipase (EL) reportedly reduces HDL
Autor:
Maki Iizuka, Kazuo Kondo, Haruyo Yamaguchi, Fumihiko Yoshie, Seiji Nagumo, Akira Iizuka, Sakae Amagaya, Takaaki Yasuda
Publikováno v:
American Journal of Plant Sciences. :454-459
We previously reported that Dai-saiko-to (Da-Chai-Hu-Tang), a traditional Japanese kampo medicine, increased LDL receptor mRNA expression in the liver of the hypercholesterolemic rabbits. In this study, we focused on LDL receptor gene expression in a
Autor:
Harumi Uto-Kondo, Hiroyuki Kagechika, Makoto Sasaki, Tsuyoshi Nakanishi, Tetsuya Hisada, Yoshinari Uehara, Maki Iizuka, Emi Yakushiji, Shunichi Takiguchi, Makiko Yogo, Kazuhiro Nakaya, Masatsune Ogura, Katsunori Ikewaki, Yoshio Terao, Makoto Ayaori, Tomohiro Komatsu
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1821:561-572
ABC transporter G1 (ABCG1) plays a pivotal role in HDL-mediated cholesterol efflux and atherogenesis. We investigated whether, and how, retinoic acid receptors (RARs) regulate ABCG1 expression in macrophages. All-trans retinoic acid (ATRA), an RAR li
Autor:
Emi Saita, Yoshimi Kishimoto, Kazuo Kondo, Mariko Tani, Miku Toyozaki, Norie Sugihara, Maki Iizuka
Publikováno v:
Journal of Oleo Science. 61:113-120
Perilla (Perilla frutescens (L.) Britt.) is a popular food as well as a traditional medicine in Japan, China, and other Asian countries. The aim of this study was to investigate the inhibitory effects of perilla on low-density lipoprotein (LDL) oxida
Autor:
Makoto Ayaori, Seibu Mochizuki, Hideki Ozasa, Masatsune Ogura, Shunichi Takiguchi, Michihiro Yoshimura, Makoto Sasaki, Shunpei Horii, Yoshio Terao, Tomohiro Komatsu, Yoshinari Uehara, Harumi Uto-Kondo, Tetsuya Hisada, Kazuhiro Nakaya, Maki Iizuka, Katsunori Ikewaki, Emi Yakushiji
Publikováno v:
Atherosclerosis. 219:141-150
Objective Pioglitazone, a peroxisome proliferator-activated receptor γ (PPARγ) agonist, reportedly reduces cardiovascular events in diabetic patients. ATP cassette binding transporters (ABC) A1 and G1 are pivotal molecules for cholesterol efflux (C
Autor:
Kazuhiro Nakaya, Tetsuya Hisada, Yoshio Terao, Emi Yakushiji, Fumitaka Ohsuzu, Makoto Sasaki, Masatsune Ogura, Makoto Ayaori, Shunichi Takiguchi, Hideki Ozasa, Harumi Uto-Kondo, Katsunori Ikewaki, Tomohiro Komatsu, Maki Iizuka
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 31:1980-1987
Objective— ATP-binding cassette transporter A1 (ABCA1) and ABCG1 are key molecules in an initial step of reverse cholesterol transport (RCT), a major antiatherogenic property of high-density lipoprotein (HDL). The ubiquitin-proteasome system (UPS)
Autor:
Motoya Ikeguchi, Miu Nagai, Miku Toyozaki, Emi Saita, Kazuo Kondo, Yoshimi Kishimoto, Mariko Tani, Tomoyasu Kamiya, Maki Iizuka
Publikováno v:
Journal of Clinical Biochemistry and Nutrition
Sweet potato (Ipomoea batatas L.) leaves are consumed as vegetables around the world, especially in Southeast Asia. The aim of this study was to investigate the inhibitory effect of sweet potato leaves on low-density lipoprotein oxidation in vitro an
Publikováno v:
Journal of Nutritional Science and Vitaminology. 56:421-427
Oxidized low-density lipoprotein (LDL) is believed to contribute to atherosclerosis in part by being taken up into macrophages via scavenger receptors, thus accounting for foam cells. Balsamic vinegar is made from grapes and generally consumed in the
Autor:
Harumi Uto-Kondo, Yoshimi Kishimoto, Maki Iizuka, Hideaki Kurata, Hirohito Sone, Mariko Tani, Kazuo Kondo, Emi Saita
Publikováno v:
European Journal of Nutrition. 49:119-126
Astaxanthin is a red carotenoid pigment which has significant potential for antioxidant activity. The macrophages in atherosclerotic lesions, known as activated macrophages, express scavenger receptors responsible for the clearance of pathogenic lipo
Autor:
Maki Iizuka, Yoshio Terao, Katsunori Ikewaki, Emi Yakushiji, Kosuke Hagisawa, Masatsune Ogura, Makiko Yogo, Makoto Sasaki, Harumi Uto-Kondo, Shunichi Takiguchi, Tomohiro Komatsu, Makoto Ayaori, Kazuhiro Nakaya
Publikováno v:
Arteriosclerosis, thrombosis, and vascular biology. 34(6)
Objective— Low-density lipoprotein receptor (LDLR) is degraded by inducible degrader of LDLR (Idol) and protein convertase subtilisin/kexin type 9 (PCSK9), thereby regulating circulating LDL levels. However, it remains unclear whether, and if so ho