Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Maki, Miyamoto"'
Autor:
Maki Miyamoto1, Yamada, Tomohito J.2 miyamoto@elms.hokudai.ac.jp
Publikováno v:
Hydrological Research Letters. 2024, Vol. 18 Issue 1, p28-34. 7p.
Autor:
Takao Mandai, Yuu Sako, Emi Kurimoto, Yuji Shimizu, Minoru Nakamura, Makoto Fushimi, Ryouta Maeda, Maki Miyamoto, Haruhide Kimura
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 1, Pp n/a-n/a (2020)
Abstract M1 muscarinic acetylcholine receptor (M1R) activation can be a new therapeutic approach for the treatment of cognitive deficits associated with cholinergic hypofunction. However, M1R activation causes gastrointestinal (GI) side effects in an
Externí odkaz:
https://doaj.org/article/1996db5c1bb74209a2c1a0e72f2d9b18
Autor:
Kenichi Iwai, Masahiro Yaguchi, Kazuho Nishimura, Yukiko Yamamoto, Toshiya Tamura, Daisuke Nakata, Ryo Dairiki, Yoichi Kawakita, Ryo Mizojiri, Yoshiteru Ito, Moriteru Asano, Hironobu Maezaki, Yusuke Nakayama, Misato Kaishima, Kozo Hayashi, Mika Teratani, Shuichi Miyakawa, Misa Iwatani, Maki Miyamoto, Michael G Klein, Wes Lane, Gyorgy Snell, Richard Tjhen, Xingyue He, Sai Pulukuri, Toshiyuki Nomura
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 6, Pp 1-15 (2018)
Abstract The modulation of pre‐mRNA splicing is proposed as an attractive anti‐neoplastic strategy, especially for the cancers that exhibit aberrant pre‐mRNA splicing. Here, we discovered that T‐025 functions as an orally available and potent
Externí odkaz:
https://doaj.org/article/5f979a579b0246ad90c5cfcded6e406d
Publikováno v:
Respirology Case Reports, Vol 7, Iss 7, Pp n/a-n/a (2019)
Nocardiosis is an uncommon infection caused by Nocardia species, but it can often occur in immunocompromised patients. As computed tomography (CT) findings of pulmonary nocardiosis, consolidation, masses, and nodules are often found, but lymph node e
Externí odkaz:
https://doaj.org/article/5d85f10a0a3a4adb83cc4c3a967fdef7
Autor:
Cristian Constantinescu, David Alagille, Caroline Papin, Eiji Sunahara, Shuhei Ikeda, Tatsuki Koike, Maki Miyamoto, John Seibyl, Gilles Tamagnan, Olivier Barret, Thomas J. Morley, Krista Fowles, Patricia E. Cole, Takanobu Kuroita, Toshiya Nishi
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 49:1148-1156
Purpose Cholesterol 24-hydroxylase (CH24H) is a brain-specific enzyme that plays a major role in brain cholesterol homeostasis by converting cholesterol into 24S-hydroxycholesterol. The selective CH24H inhibitor soticlestat (TAK-935) is being pursued
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c3b49ad503abe1c9b276111d06b8346
https://doi.org/10.1007/s00259-021-05565-z
https://doi.org/10.1007/s00259-021-05565-z
Autor:
Tomohiro Ohashi, Tomoteru Yamasaki, Yasuyuki Debori, Tatsuki Koike, Tomokazu Kusumoto, Ryouta Maeda, Masayuki Fujinaga, Akito Hata, Takeshi Wakabayashi, Yasushi Hattori, Ming-Rong Zhang, Miyanohana Yuhei, Ryo Yamashita, Maki Miyamoto, Yiding Zhang, Hidekatsu Wakizaka
Publikováno v:
Journal of Medicinal Chemistry. 64:11990-12002
Diacylglycerol kinase gamma (DGKγ) is a subtype of DGK enzyme, which catalyzes ATP-dependent conversion of diacylglycerol to phosphatidic acid. DGKγ, localized in the brain, plays an important role in the central nervous system. However, its functi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8fed7abf826a7d32a1858fd3c81b3bef
https://doi.org/10.1021/acs.jmedchem.1c00584
https://doi.org/10.1021/acs.jmedchem.1c00584
Publikováno v:
High Voltage (2017)
Cable-grade silicone rubber was aged thermally or by combining heat and gamma-ray radiation, and resultant changes in chemical, thermal, mechanical and electrical properties were examined. The experimental results obtained in these analyses are clear
Externí odkaz:
https://doaj.org/article/80669563b2cf4c8289e35b19d868951a
Autor:
Toshiya Nishi, Cameron S. Metcalf, Shinji Fujimoto, Shigeo Hasegawa, Maki Miyamoto, Eiji Sunahara, Sayuri Watanabe, Shinichi Kondo, H. Steve White
Publikováno v:
Epilepsia. 63(6)
The formation of 24S-hydroxycholesterol is a brain-specific mechanism of cholesterol catabolism catalyzed by cholesterol 24-hydroxylase (CYP46A1, also known as CH24H). CH24H has been implicated in various biological mechanisms, whereas pharmacologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af5fc7b5260a91d1b998d234df7d07e8
https://pubmed.ncbi.nlm.nih.gov/35316533
https://pubmed.ncbi.nlm.nih.gov/35316533
Autor:
Yuichi Kajita, Shuhei Ikeda, Masato Yoshikawa, Hiromi Fukuda, Etsurou Watanabe, Jason Yano, Weston Lane, Maki Miyamoto, Tsuyoshi Ishii, Toshiya Nishi, Tatsuki Koike
Publikováno v:
Journal of medicinal chemistry. 65(4)
Cholesterol 24-hydroxylase (CH24H or CYP46A1) is a brain-specific cytochrome P450 enzyme that metabolizes cholesterol into 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81a6c4f36dcf3e4b71cc12b4e8c047b9
https://pubmed.ncbi.nlm.nih.gov/35166541
https://pubmed.ncbi.nlm.nih.gov/35166541
Autor:
Maki Miyamoto, Tomohito J. Yamada
Publikováno v:
IOP Conference Series: Earth and Environmental Science. 1136:012023
Atmospheric fronts play an important role on the day-to-day variation of rainfall in Japan, North-western Pacific. They are defined as a discrepancy of air density and have been depicted on surface weather charts for more than 100 years by Japan Mete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f96b5f62b532fc1bb3a416c0c0839f73
https://doi.org/10.1088/1755-1315/1136/1/012023
https://doi.org/10.1088/1755-1315/1136/1/012023