Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Makheni Jean-Pierre"'
Autor:
Stephen J. Gaudino, Ankita Singh, Huakang Huang, Jyothi Padiadpu, Makheni Jean-Pierre, Cody Kempen, Tej Bahadur, Kiyoshi Shiomitsu, Richard Blumberg, Kenneth R. Shroyer, Semir Beyaz, Natalia Shulzhenko, Andrey Morgun, Pawan Kumar
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract IL-22 is critical for ameliorating obesity-induced metabolic disorders. However, it is unknown where IL-22 acts to mediate these outcomes. Here we examine the importance of tissue-specific IL-22RA1 signaling in mediating long-term high fat d
Externí odkaz:
https://doaj.org/article/dff7637b26b44e1ba5afa90bb82f7db3
Autor:
Sinu P. John, Anju Singh, Jing Sun, Makheni Jean Pierre, Lulwah Alsalih, Crystal Lipsey, Ziann Traore, Shenavia Balcom-Luker, Clinton J. Bradfield, Jian Song, Tovah E. Markowitz, Margery Smelkinson, Marc Ferrer, Iain D.C. Fraser
Publikováno v:
Cell Reports, Vol 41, Iss 1, Pp 111441- (2022)
Summary: Biologically active small molecules can impart modulatory effects, in some cases providing extended long-term memory. In a screen of biologically active small molecules for regulators of tumor necrosis factor (TNF) induction, we identify sev
Externí odkaz:
https://doaj.org/article/06f3747de2c641e5be2280b4ab2b1065
Autor:
Preet Joshi, Stephen J. Gaudino, Huakang Huang, Cody Kempen, Makheni Jean-Pierre, Hoi Tong Wong, Pawan Kumar, Michael Beaupre
Publikováno v:
J Immunol
Previous studies indicate that IL-17A plays an important role in mediating the intestinal microbiota and systemic metabolic functions. However, it is not known where IL-17RA signaling occurs to mediate these effects. To investigate this question, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc99b224c71f489e9e125405fbec39c
https://europepmc.org/articles/PMC8556717/
https://europepmc.org/articles/PMC8556717/
Publikováno v:
The Journal of Immunology. 202:181.11-181.11
Impaired signaling by IL-22 has been shown to accelerate high fat diet (HFD)-induced obesity. However, it is not known if IL-22 signaling in the intestine regulates HFD-induced metabolic disorders. To test this, intestinal epithelial-specific IL-22RA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11870cf5c303bb1618dbcf8324f6c521
https://doi.org/10.4049/jimmunol.202.supp.181.11
https://doi.org/10.4049/jimmunol.202.supp.181.11