The diagnostic workup of children with the radiologically isolated syndrome differs by age and by sex.

Autor: Makhani N; Department of Pediatrics, Yale University, LMP 3088, 333 Cedar Street, New Haven, CT, 06520, USA. Naila.makhani@yale.edu.; Department of Neurology, Yale University, New Haven, CT, USA. Naila.makhani@yale.edu., Lebrun-Frenay C; CRCSEP Neurologie Pasteur 2, CHU de Nice, Université Cote d'Azur, UMR2CA (URRIS), Nice, France., Siva A; Neuroimmunology Unit, Neurology Department, Istanbul University Cerrahpasa School of Medicine, Istanbul, Turkey., Shabanova V; Department of Pediatrics, Yale University, LMP 3088, 333 Cedar Street, New Haven, CT, 06520, USA., Wassmer E; Neurology Department, Birmingham Children's Hospital, Aston University, Birmingham, UK., Santoro JD; Department of Neurology, Keck School of Medicine of the University of Southern California, Los Angeles, USA.; Division of Neurology, Department of Pediatrics, Children's Hospital of Los Angeles, Los Angeles, USA., Narula S; Children's Hospital of Philadelphia, University of Pennsylvania, Philadelphia, USA., Brenton JN; Department of Neurology, University of Virginia, Charlottesville, USA., Mar S; Department of Neurology, Washington University School of Medicine, St. Louis, USA., Durand-Dubief F; Service de sclérose en plaques, Pathologies de la myéline et Neuro-Inflammation, Hôpital Neurologique, Groupement Hospitalier Est, 59 Bd Pinel, 69677, BRON Cedex, France., Zephir H; Inserm UMR-S 1172 LilNcog, Lille University Hospital FHU Precise, Lille University, Lille, France., Mathey G; Department of Neurology, Nancy University Hospital, 54035, Nancy, France., Rojas JI; Hospital Universitario de CEMIC, Buenos Aires, Argentina., de Seze J; Department of Neurology, Hospital Hautepierre, CHU de Strasbourg and Clinical Investigation Center (CIC) INSERM 1434, Strasbourg, France., Tenembaum S; Department of Neurology, National Pediatric Hospital Dr. Juan P Garrahan, Buenos Aires, Argentina., Stone RT; Department of Neurology, University of Rochester Medical Center, Rochester, USA., Casez O; Neurology MS Clinic Grenoble, Grenoble Alpes University Hospital, Grenoble, France.; T-RAIG, TIMC-IMAG, Grenoble Alpes University, Grenoble, France., Carra-Dallière C; Neurology MS Clinic, Montpellier University Hospital, 34295, Montpellier, France.; University of Montpellier (MUSE), 34295, Montpellier, France., Neuteboom RF; Department of Neurology, Erasmus MC Rotterdam, Sophia's Children's Hospital, Rotterdam, The Netherlands., Ahsan N; Department of Neurology, Keck School of Medicine of the University of Southern California, Los Angeles, USA.; Division of Neurology, Department of Pediatrics, Children's Hospital of Los Angeles, Los Angeles, USA., Arroyo HA; Department of Neurology, Hospital de Pediatría SAMIC. Prof. Dr. J.P. Garrahan, Buenos Aires, Argentina., Cabre P; Centre Hospitalo Universitaire, Fort-de-France, Martinique., Gombolay G; Division of Neurology, Department of Pediatrics, Emory University and Children's Healthcare of Atlanta, Atlanta, GA, USA., Inglese M; Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health Department of Neuroscience (DINOGMI), University of Genova, Genoa, Italy.; IRCCS Ospedale Policlinico San Martino, Genoa, Italy., Louapre C; Assistance Publique Hôpitaux de Paris, Inserm, CNRS, Hôpital de la Pitié Salpêtrière, CIC Neurosciences, Sorbonne Université, Paris Brain Institute - ICM, Paris, France., Margoni M; Department of Neurosciences, Multiple Sclerosis Center of the Veneto Region, University Hospital-School of Medicine, Padua, Italy., Palavra F; Center for Child Development - Neuropaediatrics Unit, Hospital Pediátrico, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal., Pohl D; Division of Neurology, Children's Hospital of Eastern Ontario, Ottawa, Canada., Reich DS; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, USA., Ruet A; Department of Neurology, CHU Bordeaux, Bordeaux, France.; INSERM, Neurocentre Magendie, University of Bordeaux, U1215, Bordeaux, France., Thouvenot E; Department of Neurology, Nîmes University Hospital, Nîmes, France.; IGF, University of Montpellier, CNRS, INSERM, Montpellier, France., Timby N; Department of Clinical Sciences/Pediatrics, Umeå University, Umeå, Sweden., Tintore M; Neurology Department, MS Center of Catalunya Cemcat, Vall d'Hebron University Hospital, Universitat Autònoma de Barcelona (UAB), UVIC-Universitat Central de Catalunya, Barcelona, Spain., Uygunoglu U; Neuroimmunology Unit, Neurology Department, Istanbul University Cerrahpasa School of Medicine, Istanbul, Turkey., Vargas W; Department of Neurology, Columbia University Medical Center, New York, USA., Venkateswaran S; Division of Neurology, Children's Hospital of Eastern Ontario, Ottawa, Canada., Verhelst H; Division of Pediatric Neurology, Department of Pediatrics, University Hospital Ghent, Ghent, Belgium., Wickstrom R; Neuropaediatric Unit, Department of Women's and Children's Health, Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden., Azevedo CJ; Department of Neurology, Keck School of Medicine of the University of Southern California, Los Angeles, USA., Kantarci O; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Shapiro ED; Department of Pediatrics, Yale University, LMP 3088, 333 Cedar Street, New Haven, CT, 06520, USA., Okuda DT; Department of Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center, Dallas, USA., Pelletier D; Department of Neurology, Keck School of Medicine of the University of Southern California, Los Angeles, USA.

Publikováno v: Journal of neurology [J Neurol] 2024 Jul; Vol. 271 (7), pp. 4019-4027. Date of Electronic Publication: 2024 Apr 02.

From the prodromal stage of multiple sclerosis to disease prevention.

Autor: Marrie RA; Department of Internal Medicine, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada. rmarrie@hsc.mb.ca.; Department of Community Health Sciences, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada. rmarrie@hsc.mb.ca., Allegretta M; National Multiple Sclerosis Society, New York, NY, USA., Barcellos LF; Division of Epidemiology and Genetic Epidemiology and Genomics Laboratory, School of Public Health, University of California Berkeley, Berkeley, CA, USA.; Kaiser Permanente Division of Research, Oakland, CA, USA., Bebo B; National Multiple Sclerosis Society, New York, NY, USA., Calabresi PA; Johns Hopkins University School of Medicine, Departments of Neurology, Neuroscience and Ophthalmology, Baltimore, MD, USA., Correale J; Department of Neurology, Fleni, Buenos Aires, Argentina., Davis B; Multiple Sclerosis Society of Canada, Toronto, Ontario, Canada., De Jager PL; Multiple Sclerosis Center, Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Irving Medical Center, New York, NY, USA., Gasperi C; Department of Neurology, Klinikum rechts der Isar, TUM School of Medicine, Technical University of Munich, Munich, Germany., Greenbaum C; Center for Interventional Immunology and Diabetes Program, Benaroya Research Institute, Seattle, WA, USA., Helme A; Multiple Sclerosis International Federation, London, UK., Hemmer B; Department of Neurology, Klinikum rechts der Isar, TUM School of Medicine, Technical University of Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Kanellis P; Multiple Sclerosis Society of Canada, Toronto, Ontario, Canada., Kostich W; National Multiple Sclerosis Society, New York, NY, USA., Landsman D; National Multiple Sclerosis Society, New York, NY, USA., Lebrun-Frenay C; CHU de Nice Pasteur 2, CRCSEP, UR2CA-URRIS, Université Nice Cote d'Azur Nice, Nice, France., Makhani N; Departments of Pediatrics and Neurology, Yale School of Medicine, New Haven, CT, USA., Munger KL; Department of Nutrition, Harvard TH Chan School of Public Health, Boston, MA, USA., Okuda DT; The University of Texas Southwestern Medical Center, Department of Neurology, Neuroinnovation Program, Multiple Sclerosis and Neuroimmunology Imaging Program, Dallas, TX, USA., Ontaneda D; Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic, Cleveland, OH, USA., Postuma RB; Department of Neurology, McGill University, Montreal, Quebec, Canada., Quandt JA; Department of Pathology and Laboratory Medicine, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Roman S; Patient representative, Vancouver, British Columbia, Canada., Saidha S; Division of Neuroimmunology and Neurological Infections, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Sormani MP; Department of Health Sciences, University of Genova, and IRCCS Ospedale Policlinico San Martino, Genova, Italy., Strum J; RealTalk MS, Long Beach, CA, USA., Valentine P; Multiple Sclerosis Society of Canada, Toronto, Ontario, Canada., Walton C; MS Society, London, UK., Zackowski KM; National Multiple Sclerosis Society, New York, NY, USA., Zhao Y; Faculty of Medicine (Neurology), University of British Columbia, Vancouver, British Columbia, Canada., Tremlett H; Faculty of Medicine (Neurology), University of British Columbia, Vancouver, British Columbia, Canada.

Publikováno v: Nature reviews. Neurology [Nat Rev Neurol] 2022 Sep; Vol. 18 (9), pp. 559-572. Date of Electronic Publication: 2022 Jul 15.

Radiologically isolated syndrome.

Autor: Lebrun-Frenay C; CRC-SEP Nice, Neurologie CHU Nice, Hôpital Pasteur 2, UMR2CA-URRIS, Université Côte d'Azur, Nice, France. Electronic address: lebrun-frenay.c@chu-nice.fr., Kantarci O; Mayo Clinic, Rochester, MN, USA., Siva A; Department of Neurology, Cerrahpasa School of Medicine, Istanbul University, Turkiye., Azevedo CJ; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Makhani N; Departments of Pediatrics and Neurology, Yale School of Medicine, New Haven, CT, USA., Pelletier D; Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Okuda DT; Department of Neurology, The University of Texas Southwestern Medical Center, Dallas, TX, USA.

Publikováno v: The Lancet. Neurology [Lancet Neurol] 2023 Nov; Vol. 22 (11), pp. 1075-1086. Date of Electronic Publication: 2023 Oct 12.

The radiologically isolated syndrome: revised diagnostic criteria.

Autor: Lebrun-Frénay C; Neurology MS Clinic Nice, Pasteur 2 University Hospital, UR2CA-URRIS, Côte d'Azur University, Nice 06002, France., Okuda DT; Neuroinnovation Program, Multiple Sclerosis, and Neuroimmunology Imaging Program, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., Siva A; Department of Neurology, Istanbul University Cerrahpasa School of Medicine, 34098 Istanbul, Turkey., Landes-Chateau C; Neurology MS Clinic Nice, Pasteur 2 University Hospital, UR2CA-URRIS, Côte d'Azur University, Nice 06002, France., Azevedo CJ; Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Mondot L; Neurology MS Clinic Nice, Pasteur 2 University Hospital, UR2CA-URRIS, Côte d'Azur University, Nice 06002, France., Carra-Dallière C; Neurology MS Clinic, Montpellier University Hospital, 34295 Montpellier, France.; University of Montpellier (MUSE), 34295 Montpellier, France., Zephir H; Inserm UMR-S 1172 LilNcog, Lille University, Lille University Hospital Precise, 59000 Lille, France., Louapre C; Department of Neurology, Sorbonne University, AP-HP, Pitié-Salpêtrière Hospital, 75013 Paris, France., Durand-Dubief F; Neurology MS Clinic, Neurological Hospital Pierre Wertheimer, Lyon University Hospital, 69500 Lyon/Bron, France., Le Page E; Neurology MS Clinic Rennes, Clinical Investigation Centre CIC-P 1414, Rennes University Hospital, 35000 Rennes, France., Bensa C; Neurology, Rothschild Foundation, 75019 Paris, France., Ruet A; Neurology MS Clinic Bordeaux, University Hospital, 33000 Bordeaux, France.; Neurocentre Magendie, Bordeaux University, INSERM, U1215, 33000 Bordeaux, France., Ciron J; Neurology MS Clinic, Toulouse University Hospital, 31300 Toulouse, France.; Infinity, INSERM UMR1291, CNRS UMR5051, Toulouse III University, 31300 Toulouse, France., Laplaud DA; Neurology, Nantes University Hospital, CIC1314 INSERM, 44000 Nantes, France.; CR2TI INSERM U1064, Nantes University, 44000 Nantes, France., Casez O; Neurology MS Clinic Grenoble, Grenoble Alpes University Hospital, 38700 Grenoble, France.; T-RAIG, TIMC-IMAG, Grenoble Alpes University, 38700 Grenoble, France., Mathey G; Neurology, Nancy University Hospital, 54000 Nancy, France.; Vandoeuvre-Lès-Nancy, Lorraine University, EA 4360 APEMAC, 54000 Nancy, France., de Seze J; Clinical Investigation Center, Neurology, Strasbourg University Hospital, INSERM 1434, 67200 Strasbourg, France., Zeydan B; Neurology and Radiology, Mayo Clinic, Rochester, MN 55905, USA., Makhani N; Pediatrics and Neurology, Yale School of Medicine, New Haven, CT 06510, USA., Tutuncu M; Department of Neurology, Istanbul University Cerrahpasa School of Medicine, 34098 Istanbul, Turkey., Levraut M; Neurology MS Clinic Nice, Pasteur 2 University Hospital, UR2CA-URRIS, Côte d'Azur University, Nice 06002, France., Cohen M; Neurology MS Clinic Nice, Pasteur 2 University Hospital, UR2CA-URRIS, Côte d'Azur University, Nice 06002, France., Thouvenot E; Neurology, Nîmes University Hospital, 30900 Nîmes, France.; IGF, Montpellier University, CNRS, INSERM, 34295 Montpellier, France., Pelletier D; Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA., Kantarci OH; Neurology, Mayo Clinic, Rochester, MN 55905, USA.

Publikováno v: Brain : a journal of neurology [Brain] 2023 Aug 01; Vol. 146 (8), pp. 3431-3443.

The multiple sclerosis prodrome.

Autor: Makhani N; Departments of Pediatrics and of Neurology, Yale School of Medicine, New Haven, CT, USA., Tremlett H; Faculty of Medicine (Neurology), The Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC, Canada. helen.tremlett@ubc.ca.

Publikováno v: Nature reviews. Neurology [Nat Rev Neurol] 2021 Aug; Vol. 17 (8), pp. 515-521. Date of Electronic Publication: 2021 Jun 21.