Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Makenzie T. Lewis"'
Autor:
Daniel S. Barth, Kirk W. Johnson, Lisa I. Greene, Peter M. Grace, Hang Yin, Linda R. Watkins, Mark R. Hutchinson, Xiaohui Wang, Keith A. Strand, Khara M. Ramos, Kelly N. Morgan, Yingning Zhang, Juliet L. Kroll, Debra Berkelhammer, Thomas A. Cochran, Kenner C. Rice, Krista M. Rodgers, Madeline G. Huey, Steven F. Maier, Frederick R. Taylor, Makenzie T. Lewis
Publikováno v:
Neuroscience. 280:299-317
CNS immune signaling contributes to deleterious opioid effects including hyperalgesia, tolerance, reward, and dependence/withdrawal. Such effects are mediated by opioid signaling at toll-like receptor 4 (TLR4), presumptively of glial origin. Whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6a32988b48a09ae40e247e205616eb
https://doi.org/10.1016/j.neuroscience.2014.09.020
https://doi.org/10.1016/j.neuroscience.2014.09.020
Autor:
Mark R. Hutchinson, Paige W. Sholar, Khara M. Ramos, Makenzie T. Lewis, Kenner C. Rice, Nicole Y. Crysdale, Julie Wieseler, Yingning Zhang, Steven F. Maier, Lisa C. Loram, Linda R. Watkins, Jacqueline A. Harrison, Jeffrey J. Kearney
Publikováno v:
Neuroscience. 164:1821-1832
Spinal cord microglial toll-like receptor 4 (TLR4) has been implicated in enhancing neuropathic pain and opposing morphine analgesia. The present study was initiated to explore TLR4-mediated pain modulation by intrathecal lipopolysaccharide, a classi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b6f7ba0c47a0450264f9b440e2a8491
https://doi.org/10.1016/j.neuroscience.2009.09.046
https://doi.org/10.1016/j.neuroscience.2009.09.046
Autor:
Khara M. Ramos, Evan M. Sloane, Jacqueline A. Harrison, Juliet L. Kroll, Makenzie T. Lewis, Linda R. Watkins, Steven F. Maier, Frederick R. Taylor, Kelly N. Morgan, Nicole Y. Crysdale
Publikováno v:
Neuroscience. 169(4)
Glutamate neurotransmission is highly regulated, largely by glutamate transporters. In the spinal cord, the glutamate transporter GLT-1 is primarily responsible for glutamate clearance. Downregulation of GLT-1 can occur in activated astrocytes, and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53e48ba2aa29a400e543e426ac33335
https://pubmed.ncbi.nlm.nih.gov/20547213
https://pubmed.ncbi.nlm.nih.gov/20547213
Autor:
Evan M. Sloane, Erin D. Milligan, Luke D. Amer, Linda R. Watkins, Scott M. Johnson, Stephen Poole, Makenzie T. Lewis, Jacqueline A. Harrison, Ellen C. Dengler, Courtney S. Young, Melissa J. Mahoney, Lisa C. Loram, Ryan G. Soderquist, Matthew G. Frank
Publikováno v:
Pharmaceutical research. 27(5)
Interleukin-10 (IL-10) is an anti-inflammatory molecule that has achieved interest as a therapeutic for neuropathic pain. In this work, the potential of plasmid DNA-encoding IL-10 (pDNA-IL-10) slowly released from biodegradable microparticles to prov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4453bba4248739cceee76f2e770e1633
https://pubmed.ncbi.nlm.nih.gov/20224990
https://pubmed.ncbi.nlm.nih.gov/20224990