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Publikováno v:
Journal of Lipid Research, Vol 65, Iss 6, Pp 100555- (2024)
Cytochrome P450 46A1 (CYP46A1) is the CNS-specific cholesterol 24-hydroxylase that controls cholesterol elimination and turnover in the brain. In mouse models, pharmacologic CYP46A1 activation with low-dose efavirenz or by gene therapy mitigates the
Externí odkaz:
https://doaj.org/article/c33367ff731c493e950729642ca5ebf6