Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Makarand Bagul"'
Autor:
Emilio Russo, Paula Martinez Agredano, Peter Flachenecker, Charlotte Lawthom, Duncan Munro, Chandni Hindocha, Makarand Bagul, Eugen Trinka
Publikováno v:
Journal of Cannabis Research, Vol 6, Iss 1, Pp 1-13 (2024)
Abstract Background Use of cannabis-based products is becoming more frequent, and it is important that healthcare professionals are informed and confident about them when making evidence-based decisions about their use. This study aimed to gain an in
Externí odkaz:
https://doaj.org/article/d040ad7061ba4ecd818be674830d4cc2
Autor:
Clara Grazia Chisari, Joe Guadagno, Peyman Adjamian, Carlos Vila Silvan, Teresa Greco, Makarand Bagul, Francesco Patti
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 16 (2023)
Background: Over 80% of individuals with multiple sclerosis (MS) experience MS-associated spasticity (MSS). In many European countries, after failure of first-line treatments, moderate or severe MSS can be treated with nabiximols, a cannabis-based ad
Externí odkaz:
https://doaj.org/article/ac888780ed304cd2a775d85a52dfd25f
Autor:
Francisco Javier Carod-Artal, Peyman Adjamian, Carlos Vila Silván, Makarand Bagul, Claudio Gasperini
Publikováno v:
Expert review of neurotherapeutics. 22(6)
Spasticity is a common, debilitating symptom of multiple sclerosis (MS) with several treatment options including the cannabinoid-based treatment, nabiximols. The purpose of this review was to examine the existing clinical practice guidelines that dir
Autor:
Vicente Villanueva, Dinesh Kumar, Lieven Lagae, Antonio Laurenza, Makarand Bagul, Haichen Yang, Kimford J. Meador
Publikováno v:
Epilepsia. 57:1120-1129
SummaryObjective The noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonist perampanel was shown in phase III trials to be an effective and well-tolerated adjunctive treatment for partial-onset seizures. In ad
Autor:
David Squillacote, Jin Zhu, Elinor Ben-Menachem, Jean François Clément, Emilio Perucca, Xuefeng Wang, Makarand Bagul, Gregory L. Krauss, Jerry J. Shih, Michelle L. Gee, Patrick Kwan
Publikováno v:
Epilepsia
SummaryObjective To evaluate safety, tolerability, seizure frequency, and regional variations in treatment responses with the AMPA antagonist, perampanel, in a large extension study during up to 3 years of treatment. Methods Patients ≥12 years old
Autor:
Richard S. McLachlan, Neelan Pillay, Michelle Gee, Jin Zhu, Makarand Bagul, Jean-François Clément, Paul A. Hwang, Gregory L. Krauss
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 85:e4.188-e4
Purpose Extending perampanel long-term safety/tolerability data, with an additional 10 months (cut-off Oct 2011). Methods Participants in study 307 (NCT00735397) had completed a Phase III perampanel trial, and were titrated to 12 mg/day (or individua
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 85:e4.179-e4
Purpose To assess the long-term safety and efficacy of zonisamide versus carbamazepine monotherapy for partial seizures in adults with newly diagnosed epilepsy. Method Adult patients completing a Phase III, randomised, double-blind, non-inferiority t
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 85:e4.181-e4
Purpose Extending duration of analysis with up to two years perampanel exposure. Methods We report 7260 additional patient-months (cut-off Oct 2011) from extension study 307 (NCT00735397). Seizure outcomes were analysed in 13-week intervals (time fro