Výsledky vyhledávání - "Major histocompatibility antigen class 2"

Major Histocompatibility Complex Class II (DRB3) Genetic Diversity in Spanish Morucha and Colombian Normande Cattle Compared to Taurine and Zebu Populations

Autor: Michel David Bohórquez, Diego Ordoñez, Carlos Fernando Suárez, Belén Vicente, Carmen Vieira, Julio López-Abán, Antonio Muro, Iván Ordóñez, Manuel Alfonso Patarroyo

Publikováno v: Frontiers in Genetics, Vol 10 (2020)
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario
Repositorio Institucional UDCA
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
instacron:Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Frontiers in Genetics

Bovine leukocyte antigens (BoLA) have been used as disease markers and immunological traits in cattle due to their primary role in pathogen recognition by the immune system. A higher MHC allele diversity in a population will allow presenting a broade

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59059ee828d5234be473d61932165618
https://www.frontiersin.org/article/10.3389/fgene.2019.01293/full

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Epitope Prediction Assays Combined with Validation Assays Strongly Narrows down Putative Cytotoxic T Lymphocyte Epitopes

Autor: Peng Peng Ip, Hans W. Nijman, Toos Daemen

Publikováno v: Vaccines
Volume 3
Issue 2
Pages 203-220
Vaccines, 3(2), 203-220. MDPI AG
Vaccines, Vol 3, Iss 2, Pp 203-220 (2015)

Tumor vaccine design requires prediction and validation of immunogenic MHC class I epitopes expressed by target cells as well as MHC class II epitopes expressed by antigen-presenting cells essential for the induction of optimal immune responses. Epit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb257496d65414b5fc9a20e46ff9a26
https://doi.org/10.3390/vaccines3020203

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Architectural Insight into Inovirus-Associated Vectors (IAVs) and Development of IAV-Based Vaccines Inducing Humoral and Cellular Responses: Implications in HIV-1 Vaccines

Autor: Hassapis, K. A., Stylianou, Dora C., Kostrikis, Leontios G.

Publikováno v: Viruses, Vol 6, Iss 12, Pp 5047-5076 (2014)
Viruses

Inovirus-associated vectors (IAVs) are engineered, non-lytic, filamentous bacteriophages that are assembled primarily from thousands of copies of the major coat protein gp8 and just five copies of each of the four minor coat proteins gp3, gp6, gp7 an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae16d66ea7c11aadd0c936516cf7292
http://www.mdpi.com/1999-4915/6/12/5047

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The high immunogenicity induced by modified sporozoites’ malarial peptides depends on their phi (ϕ) and psi (ψ) angles

Autor: Martha Patricia Alba, Adriana Bermúdez, Manuel E. Patarroyo

Publikováno v: Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario

The importance of CSP- and STARP-derived ? and ? dihedral angles in mHABP structure was analysed by 1H NMR in the search for molecules which can be included as components of a first-line-of-defence Plasmodium falciparum sporozoite multi-epitope vacci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74ca98c67e0f743d5677331b3eae5d07
https://doi.org/10.1016/j.bbrc.2012.10.088

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TCR-contacting residues orientation and HLA-DRβ* binding preference determine long-lasting protective immunity against malaria

Autor: Manuel A. Patarroyo, Martha Patricia Alba, Yahson Varela, Adriana Bermúdez, Carlos F. Suárez, Manuel E. Patarroyo

Publikováno v: Repositorio Institucional UDCA
Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
instacron:Universidad de Ciencias Aplicadas y Ambientales U.D.C.A
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario

Fully-protective, long-lasting, immunological (FPLLI) memory against Plasmodium falciparum malaria regarding immune protection-inducing protein structures (IMPIPS) vaccinated into monkeys previously challenged and re-challenged 60 days later with a l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb3fd72051c928e2e8f43be1b7acd46c
https://pubmed.ncbi.nlm.nih.gov/27363338

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Proteus and the design of ligand binding sites

Autor: Polydorides, Savvas, Michael, E., Mignon, D., Druart, Karen, Archontis, Georgios Z., Simonson, T.

Publikováno v: Methods in Molecular Biology
Methods Mol. Biol.

This chapter describes the organization and use of Proteus, a multitool computational suite for the optimization of protein and ligand conformations and sequences, and the calculation of pKα shifts and relative binding affinities. The software offer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4485::0b0e21b18662d90852bf7122816e8366
http://gnosis.library.ucy.ac.cy/handle/7/59011

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3D structure and immunogenicity of Plasmodium falciparum sporozoite induced associated protein peptides as components of fully-protective anti-malarial vaccine

Autor: Dayana Calderon, Hannia Almonacid, Edgar A. Chacón, Luis A. Poloche, Martha Patricia Alba, Manuel E. Patarroyo, Manuel A. Patarroyo

Publikováno v: Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario

SIAP-1 and SIAP-2 are proteins which are implicated in early events involving Plasmodium falciparum infection of the Anopheles mosquito vector and the human host. High affinity HeLa and HepG2 cell binding conserved peptides have been previously ident

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d53b8aec5d74d72d5a94859ccc8c54
https://doi.org/10.1016/j.bbrc.2011.11.039

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Quantum Chemical Analysis of MHC-Peptide Interactions for Vaccine Design

Autor: M E Patarroyo, W A Agudelo

Publikováno v: Mini Reviews in Medicinal Chemistry
Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario

The development of an adequate immune response against pathogens is mediated by molecular interactions between different cell types. Among them, binding of antigenic peptides to the Major Histocompatibility Complex (MHC) molecule expressed on the mem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9778d490d3f37642ea224d1ba869a96
https://doi.org/10.2174/138955710791572488

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Structural characteristics of immunogenic liver-stage antigens derived from P. falciparum malarial proteins

Autor: Camilo Pirajan, Manuel E. Patarroyo, Nora L. Martínez, Gladys Cifuentes, Magnolia Vanegas

Publikováno v: Repositorio EdocUR-U. Rosario
Universidad del Rosario
instacron:Universidad del Rosario

A fully effective antimalarial vaccine must contain multiple proteins from the different development stages of Plasmodium falciparum parasites involved in host-cell invasion or their biologically active fragments. It must therefore include sporozoite

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c559b79b8b6618b55a5d9b7034dc06
https://doi.org/10.1016/j.bbrc.2009.04.138

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