Zobrazeno 1 - 10
of 3 595
pro vyhledávání: '"Major Articles"'
Publikováno v:
J Infect Dis
Chlamydia trachomatis serovars A–L cause important diseases of the eyes and reproductive tract by infecting epithelium lining those organs. A major hurdle for vaccine trials is finding a surrogate biomarker for protective immunity. Investigational
Autor:
Ronald J, Bosch, Rajesh T, Gandhi, Hanna, Mar, Joseph J, Eron, Joshua C, Cyktor, Deborah K, McMahon, John W, Mellors
Publikováno v:
J Infect Dis
Clinical research to achieve antiretroviral therapy-free remission requires quantitative assays of the HIV-1 reservoir. Intact proviral DNA (IPD) measurement has greater throughput than the quantitative viral outgrowth assay (QVOA). In 25 individuals
Autor:
Kathrin Zürcher, Julien Riou, Carl Morrow, Marie Ballif, Anastasia Koch, Simon Bertschinger, Digby F Warner, Keren Middelkoop, Robin Wood, Matthias Egger, Lukas Fenner
Publikováno v:
J Infect Dis
Background Congregate settings, such as healthcare clinics, may play an essential role in Mycobacterium tuberculosis (Mtb) transmission. Using patient and environmental data, we studied transmission at a primary care clinic in South Africa. Methods W
Autor:
Lewis, Lisa A, Gulati, Sunita, Zelek, Wioleta M., Morgan, B. Paul, Song, Wen-Chao, Zheng, Bo, Nowak, Nancy, DeOliveira, Rosane B., Sanchez, Bryan, DeSouza Silva, Leandro, Schuurman, Janine, Beurskens, Frank, Ram, Sanjay, Rice, Peter A
Publikováno v:
J Infect Dis
A safe and effective vaccine against multidrug-resistant gonorrhea is urgently needed. An experimental peptide vaccine called TMCP2 that mimics an oligosaccharide epitope in gonococcal lipooligosaccharide, when adjuvanted with glucopyranosyl lipid ad
Autor:
Lewis, Nathaniel M, Naioti, Eric A, Self, Wesley H, Ginde, Adit A, Douin, David J, Keipp Talbot, H, Casey, Jonathan D, Mohr, Nicholas M, Zepeski, Anne, Gaglani, Manjusha, Ghamande, Shekhar A, McNeal, Tresa A, Shapiro, Nathan I, Gibbs, Kevin W, Clark Files, D, Hager, David N, Shehu, Arber, Prekker, Matthew E, Erickson, Heidi L, Gong, Michelle N, Mohamed, Amira, Henning, Daniel J, Steingrub, Jay S, Peltan, Ithan D, Brown, Samuel M, Martin, Emily T, Hubel, Kinsley, Hough, Catherine L, Busse, Laurence W, ten Lohuis, Caitlin C, Duggal, Abhijit, Wilson, Jennifer G, Gordon, Alexandra J, Qadir, Nida, Chang, Steven Y, Mallow, Christopher, Rivas, Carolina, Babcock, Hilary M, Kwon, Jennie H, Exline, Matthew C, Halasa, Natasha, Chappell, James D, Lauring, Adam S, Grijalva, Carlos G, Rice, Todd W, Rhoads, Jillian P, Stubblefield, William B, Baughman, Adrienne, Womack, Kelsey N, Lindsell, Christopher J, Hart, Kimberly W, Zhu, Yuwei, Schrag, Stephanie J, Kobayashi, Miwako, Verani, Jennifer R, Patel, Manish M, Tenforde, Mark W
Publikováno v:
J Infect Dis
Vaccine effectiveness (VE) against COVID-19 hospitalization was evaluated among immunocompetent adults (≥18 years) during March–August 2021 using a case-control design. Among 1669 hospitalized COVID-19 cases (11% fully vaccinated) and 1950 RT-PCR
Autor:
Zoe L Lyski, Amanda E Brunton, Matt I Strnad, Peter E Sullivan, Sarah A R Siegel, Fikadu G Tafesse, Mark K Slifka, William B Messer
Publikováno v:
J Infect Dis
The unprecedented severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has called for substantial investigations into the capacity of the human immune system to protect against reinfection and keep pace with the evolution of SARS-CoV
Autor:
Donna Ambrosino, Htay Htay Han, Branda Hu, Joshua Liang, Ralf Clemens, Marina Johnson, George Siber, David Goldblatt
Publikováno v:
The Journal of Infectious Diseases
A significant correlation has been shown between the binding antibody responses against original severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein and vaccine efficacy of 4 approved coronavirus disease 2019 vaccines. We there
Autor:
Simphiwe Simelane, Harukazu Suzuki, Suraj P. Parihar, Mumin Ozturk, Justin Komguep Nono, Thabo Mpotje, Sugata Roy, Shandre Pillay, Shelby-Sara Jones, Sibongiseni K L Poswayo, Julius Ebua Chia, Frank Brombacher, Reto Guler, Lerato Hlaka
Publikováno v:
The Journal of Infectious Diseases
Background Interleukin 4 (IL-4i1)–induced gene 1 encodes L-phenylalanine oxidase that catabolizes phenylalanine into phenylpyruvate. IL-4i1 is mainly expressed by antigen-presenting cells (APCs), inhibits T-cell proliferation, regulates B-cell acti
Publikováno v:
Clinical infectious diseases, 73(9), E2545-E2551. Oxford University Press
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background Recurrent bacterial meningitis has been found to occur in about 5% of meningitis cases. Methods We analyzed adults with recurrent episodes in a prospective nationwide cohort study of community-acquired bacterial meningitis. Results Of 2264
Autor:
Harold Obiakor, Shaji Daniel, Justin Doritchamou, Andrew V. Oleinikov, Tracy Saveria, Robert Morrison, Nicholas J. MacDonald, Bethany J Jenkins, Gladys J. Keitany, David L. Narum, Atis Muehlenbachs, Sanjay A. Desai, Jean-Philippe Semblat, Marissa Vignali, Benoit Gamain, Michal Fried, Patrick E. Duffy
Publikováno v:
J Infect Dis
Background Plasmodium falciparum-infected red blood cells (iRBCs) bind and sequester in deep vascular beds, causing malaria-related disease and death. In pregnant women, VAR2CSA binds to chondroitin sulfate A (CSA) and mediates placental sequestratio