Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Major, Meriel R"'
Autor:
Zhang, Jihui, Chen, Jie, Richardson, Jonathan P., Francis-Newton, Nicola-Jane, Lai, Pei F., Jenkins, Kerry, Major, Meriel R., Key, Rebekah E., Stewart, Mark E., Firth-Clark, Stuart, Lloyd, Steven M., Newton, Gary K., Perrior, Trevor R., Garrod, David R., Robinson, Clive
Publikováno v:
ACS Pharmacology & Translational Science; 9/9/2022, Vol. 5 Issue 9, p735-751, 17p
Autor:
Leese, Mathew P, Jourdan, Fabrice L, Major, Meriel R, Dohle, Wolfgang, Thomas, Mark P, Hamel, Ernest, Ferrandis, Eric, Mahon, Mary F, Newman, Simon P, Purohit, Atul, Potter, Barry V L
Publikováno v:
Chemmedchem
A SAR translation strategy adopted for the discovery of tetrahydroisoquinolinone (THIQ)-based steroidomimetic microtubule disruptors has been extended to dihydroisoquinolinone (DHIQ)-based compounds. A steroid A,B-ring-mimicking DHIQ core was connect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa321691290cabdeefa1cb52a569b091
http://europepmc.org/articles/PMC4114533
http://europepmc.org/articles/PMC4114533
Autor:
Newton, Gary K., Perrior, Trevor R., Jenkins, Kerry, Major, Meriel R., Key, Rebekah E., Stewart, Mark R., Firth-Clark, Stuart, Lloyd, Steven M., Zhang, Jihui, Francis-Newton, Nicola J., Richardson, Jonathan P., Chen, Jie, Lai, Pei, Garrod, David R., Robinson, Clive
Publikováno v:
Journal of Medicinal Chemistry
Blocking the bioactivity of allergens is conceptually attractive as a small-molecule therapy for allergic diseases but has not been attempted previously. Group 1 allergens of house dust mites (HDM) are meaningful targets in this quest because they ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::698a12a02fca16567d35ac1be5ab47fd
https://openaccess.sgul.ac.uk/id/eprint/107340/1/The_discovery_of_potent_selective_reversible_inhibitors_house_dust_mites_peptidase.pdf
https://openaccess.sgul.ac.uk/id/eprint/107340/1/The_discovery_of_potent_selective_reversible_inhibitors_house_dust_mites_peptidase.pdf
Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors
Autor:
Donahue, Elizabeth H, Dawson, Lisa F, Valiente, Esmeralda, Firth-Clark, Stuart, Major, Meriel R, Littler, Eddy, Perrior, Trevor R, Wren, Brendan W
BACKGROUND: Bacterial sortases are transpeptidases that covalently anchor surface proteins to the peptidoglycan of the Gram-positive cell wall. Sortase protein anchoring is mediated by a conserved cell wall sorting signal on the anchored protein, com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::7f22fd651245f8c237fc0f3b4a005488
https://researchonline.lshtm.ac.uk/id/eprint/1918317/1/12866_2014_Article_219.pdf
https://researchonline.lshtm.ac.uk/id/eprint/1918317/1/12866_2014_Article_219.pdf
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Newton, Gary K., Perrior, Trevor R., Jenkins, Kerry, Major, Meriel R., Key, Rebekah E., Stewart, Mark R., Firth-Clark, Stuart, Lloyd, Steven M., Zhang, Jihui, Francis-Newton, Nicola J., Richardson, Jonathan P., Chen, Jie, Lai, Pei, Garrod, David R., Robinson, Clive
Publikováno v:
Journal of Medicinal Chemistry; Nov2014, Vol. 57 Issue 22, p9447-9462, 16p
Autor:
Leese, Mathew P., Jourdan, Fabrice L., Major, Meriel R., Dohle, Wolfgang, Hamel, Ernest, Ferrandis, Eric, Fiore, Ann, Kasprzyk, Philip G., Potter, Barry V. L.
Publikováno v:
ChemMedChem; Jan2014, Vol. 9 Issue 1, p1-1, 2p