Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Majid safa"'
Autor:
Seyed Esmaeil Ahmadi, Elahe Rahimian, Samira Rahimi, Bahman Zarandi, Mehran Bahraini, Maral Soleymani, Seyed Mehrab Safdari, Ashkan Shabannezhad, Niloofar Jaafari, Majid Safa
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-60 (2024)
Abstract The p53 protein, encoded by the TP53 gene, serves as a critical tumor suppressor, playing a vital role in maintaining genomic stability and regulating cellular responses to stress. Dysregulation of p53 is frequently observed in hematological
Externí odkaz:
https://doaj.org/article/edd454dcab5842c794282c615d36013f
Autor:
Mahdi Pakjoo, Seyed Esmaeil Ahmadi, Mohammad Zahedi, Niloofar Jaafari, Reyhane Khademi, Ali Amini, Majid Safa
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-28 (2024)
Abstract The current scientific literature has extensively explored the potential role of proteasome inhibitors (PIs) in the NF-κB pathway of leukemia and lymphoma. The ubiquitin-proteasome system (UPS) is a critical component in regulating protein
Externí odkaz:
https://doaj.org/article/864fe8486ee64ea5b94ffd10fac109ce
Autor:
Seyed Esmaeil Ahmadi, Ashkan Shabannezhad, Amir Kahrizi, Armin Akbar, Seyed Mehrab Safdari, Taraneh Hoseinnezhad, Mohammad Zahedi, Soroush Sadeghi, Mahsa Golizadeh Mojarrad, Majid Safa
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-39 (2023)
Abstract Tissue factor (TF) is a protein that plays a critical role in blood clotting, but recent research has also shown its involvement in cancer development and progression. Herein, we provide an overview of the structure of TF and its involvement
Externí odkaz:
https://doaj.org/article/7ba860a27e074eb5b497cfca55d1ac0c
Autor:
Javad Firouzi, Abbas Hajifathali, Masoumeh Azimi, Neda Parvini, Fatemeh Ghaemi, Niloufar Shayan Asl, Amir Abbas Hedayati Asl, Majid Safa, Marzieh Ebrahimi
Publikováno v:
Cell Journal, Vol 25, Iss 2, Pp 92-101 (2023)
Objective: Natural killer (NK) cells are critical immune cells for acute myeloid leukemia (AML) targeting. However,little is known about the relationship between using checkpoint inhibitors and heat shock protein 70 (Hsp70) as NK cellactivators to co
Externí odkaz:
https://doaj.org/article/2301b974e96f4804b5bdef6c0cdb5896
Autor:
Somaye Fatahi, Ali Akbar Sayyari, Masoud Salehi, Majid Safa, Mohammadhassan Sohouli, Farzad Shidfar, Heitor O. Santos
Publikováno v:
BMC Pediatrics, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Chitosan is one of dietary fiber that has received great attention in improving obesity-related markers, but little is known on its effects on adolescents. Objectives To analyze the effects of chitosan supplementation on obesity-r
Externí odkaz:
https://doaj.org/article/5ab514e76fff45dfbfd1bedb6f6b4fff
Autor:
Javad Firouzi, Fattah Sotoodehnejadnematalahi, Alireza Shokouhifar, Mahsa Rahimi, Niloufar Sodeifi, Parisa Sahranavardfar, Masoumeh Azimi, Ehsan Janzamin, Majid Safa, Marzieh Ebrahimi
Publikováno v:
BioImpacts, Vol 12, Iss 5, Pp 415-429 (2022)
Introduction: Malignant breast cancer (BC) frequently contains a rare population of cells called cancer stem cells which underlie tumor relapse and metastasis, and targeting these cells may improve treatment options and outcomes for patients with BC.
Externí odkaz:
https://doaj.org/article/eb024cb36663414db814aa533912b7e6
Publikováno v:
Biotechnology Reports, Vol 38, Iss , Pp e00792- (2023)
Background: HIV-1-derived lentiviral vectors (LVs) are capable of transducing human cells by integrating the transgene into the host genome. In order to do that, LVs should have enough time and space to interact with the surface of the target cells.
Externí odkaz:
https://doaj.org/article/61cf6f15fac54afaba4cfce81f23da97
Autor:
Saba Jahangiri, Samideh Khoei, Sepideh Khoee, Majid Safa, Sakine Shirvalilou, Vahid Pirhajati Mahabadi
Publikováno v:
Cancer Nanotechnology, Vol 12, Iss 1, Pp 1-17 (2021)
Abstract Background The purpose of the present study was to evaluate the efficacy of chemo-magnetic hyperthermia (MH), a combination of alternating magnetic field (AMF) and superparamagnetic nanoparticles (SPIONs) coated with Polyethylene glycol-Poly
Externí odkaz:
https://doaj.org/article/5d74514b2824476bb81eb260e47cb894
Publikováno v:
Experimental Hematology & Oncology, Vol 10, Iss 1, Pp 1-26 (2021)
Abstract Chromosomal translocations are the main etiological factor of hematologic malignancies. These translocations are generally the consequence of aberrant DNA double-strand break (DSB) repair. DSBs arise either exogenously or endogenously in cel
Externí odkaz:
https://doaj.org/article/f65821dddac94eee87c69283e2a72504
Autor:
Ali Amirinejad, Ali Saneei Totmaj, Farzaneh Mardali, Azita Hekmatdoost, Hadi Emamat, Majid Safa, Farzad Shidfar
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide. The aim of this study was to evaluate the effects of hydro-alcoholic extract of spinach (HES) on hepatic and serum measurements of NAFLD in a rat
Externí odkaz:
https://doaj.org/article/0461428504eb47eebb5f99e8a9ce4e1b