Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Majid Mehtali"'
Autor:
Tania Sorg, Majid Mehtali
Publikováno v:
Transgenic Animals ISBN: 9781003211099
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3139ffa8ddc9202d3abc72a5cf9ec226
https://doi.org/10.1201/9781003211099-77
https://doi.org/10.1201/9781003211099-77
Autor:
Nicola Beltraminelli, Sévérine Danet, Marine Jacoby, Audrey Angel, Olivier Nerriere, Boussad Souttou, Laurent Gauthier, Fabienne Guehenneux, Stéphane Olivier, Majid Mehtali, Cédric Brillon, Thomas Mollet, Mathilde Berthomé, Henri Vié, Sylvana Bouletreau
Publikováno v:
mAbs. 2:405-415
Monoclonal antibodies (mAbs) represent the fastest growing class of therapeutic proteins. The increasing demand for mAb manufacturing and the associated high production costs call for the pharmaceutical industry to improve its current production proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b455bc75ed4f961d48dc69c3f9429b0
https://doi.org/10.4161/mabs.12350
https://doi.org/10.4161/mabs.12350
Autor:
Majid Mehtali, Stéphane Olivier
Publikováno v:
médecine/sciences. 25:1163-1168
Les anticorps monoclonaux therapeutiques commercialises ou en developpement sont produits a partir de cellules de mammiferes en culture, dont notamment la cellule de hamster CHO. Ces systemes cellulaires permettent la production industrielle de prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d513e1130c68a7c7ae633ef8fbfdeed
https://doi.org/10.1051/medsci/200925121163
https://doi.org/10.1051/medsci/200925121163
Autor:
Majid Mehtali, Giulio Cabrini, Andrea Pavirani, Patrice Diot, Elena Nicolis, Sté Phanie Lerondel, Serge Bernard, Alain Le Pape, Claude Sene, Laurence Faure, Monika Lusky
Publikováno v:
Human Gene Therapy. 12:1-11
Cystic fibrosis is a common, heriditary disease resulting from mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Airway transfer of the CFTR gene is a potential strategy to treat or prevent the lung pathology that is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de06ee3a4e75ed931547f5563ac598f
https://doi.org/10.1089/104303401450915
https://doi.org/10.1089/104303401450915
Autor:
Michael Courtney, Thierry Dorval, Pierre Pouillart, Wolf H. Fridman, P Squiban, Christoph Rochlitz, Peter Jantscheff, Eric Tartour, I Joyeux, J M Pleau, Majid Mehtali, C Mathiot, Richard Herrmann, X. Sastre-Garau
Publikováno v:
British Journal of Cancer
Various studies have emphasized an immunodepression state observed at the tumour site. To reverse this defect and based upon animal studies, we initiated a phase I clinical trial of gene therapy in which various doses of xenogeneic monkey fibroblasts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc34db2bd15e9f4b6b159dec3edc982
https://doi.org/10.1054/bjoc.2000.1492
https://doi.org/10.1054/bjoc.2000.1492
Autor:
Philippe Leissner, Laurence Kehrli, Linda Grave, Christine Rouzioux, Jean-Louis Touraine, Jean-Claude Tardy, Kamel Sanhadji, Reza Firouzi, Majid Mehtali
Publikováno v:
AIDS. 14:2813-2822
OBJECTIVE: To study the anti-HIV-1 effects of the delivery of anti-gp41 monoclonal antibody (mAb) and soluble CD4 (sCD4) immunoadhesin by genetically modified cells in HIV-1-infected, humanized severe combined immunodeficient (SCID) mice. DESIGN: The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0afc689c4f158a879237a40acbd6bf7f
https://doi.org/10.1097/00002030-200012220-00002
https://doi.org/10.1097/00002030-200012220-00002
Autor:
S Blanchard, Pierre-Olivier Vidalain, Arend Jan Winter, Philippe Leissner, François-Loïc Cosset, Jean-Luc Darlix, Didier Nègre, Chantal Rabourdin-Combe, Majid Mehtali, Ghislaine Duisit, Philippe Moullier, Philippe E. Mangeot
Publikováno v:
Gene Therapy. 7:1613-1623
We describe the generation and the characterization of new lentiviral vectors derived from SIVmac251, a simian immunodeficiency virus (SIV). A methodical approach was used to engineer both efficient and safe packaging constructs allowing the producti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a124179e6e04e6050965028fe0569420
https://doi.org/10.1038/sj.gt.3301292
https://doi.org/10.1038/sj.gt.3301292
Autor:
Lexander N Zakhartchouk, Majid Mehtali, P. Seshidhar Reddy, Suresh K. Tikoo, Lorne A. Babiuk, Neeraja Idamakanti
Publikováno v:
Virus Research
Adenoviral vectors expressing foreign genes have many desirable properties in applications such as vaccination. Recently, we have generated replication-competent (E3 deleted) bovine adenovirus-3 (BAV-3) recombinants expressing significant amounts of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::804f5538afbd5f75b4b3ea46ebf70cb6
https://doi.org/10.1016/s0168-1702(00)00209-4
https://doi.org/10.1016/s0168-1702(00)00209-4
Autor:
Dalila Ali Hadji, Fabienne Stoeckel, Dominique Dreyer, Jacqueline Kintz, Linda Grave, Majid Mehtali, Bernard Louis, A Dieterle, Monika Lusky, M. Christ
Publikováno v:
Human Gene Therapy. 11:415-427
Liver toxicity and inflammation were assessed in C57BL/6, CBA, and BALB/c mice injected intravenously with a series of recombinant adenoviruses deleted simultaneously in E1/E3, in E1/E3/E2A, or in E1/E3/E4. All vectors were either devoid of transgene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2e8ef575a3f2178449e34a8e1c72f1
https://doi.org/10.1089/10430340050015888
https://doi.org/10.1089/10430340050015888
Autor:
Anne-Isabelle Michou, Monika Lusky, Linda Grave, A Dieterle, Majid Mehtali, Andrea Pavirani, Cecile Doderer, Pierre Leroy, Dominique Dreyer
Publikováno v:
The Journal of Gene Medicine. 2:433-443
Background Strong and stable transgene expression is fundamental to the success of recombinant adenovirus vectors in human gene therapy. However, control of transgene expression is a complex process, involving both viral and cellular factors. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ed2019398931fdc448b56cb17b99fa1
https://doi.org/10.1002/1521-2254(200011/12)2:6<433::aid-jgm143>3.0.co
https://doi.org/10.1002/1521-2254(200011/12)2:6<433::aid-jgm143>3.0.co