Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Majid, Sheykhzade"'
Autor:
Jacob C. A. Edvinsson, Aida Maddahi, Isabella M. Christiansen, Philip V. Reducha, Karin Warfvinge, Majid Sheykhzade, Lars Edvinsson, Kristian A. Haanes
Publikováno v:
The Journal of Headache and Pain, Vol 23, Iss 1, Pp 1-19 (2022)
Abstract Background 5-Hydroxytryptamine (5-HT) receptors 1B, 1D and 1F have key roles in migraine pharmacotherapy. Selective agonists targeting these receptors, such as triptans and ditans, are effective in aborting acute migraine attacks and inhibit
Externí odkaz:
https://doaj.org/article/4847186bbf3c4ec384a7edc6c2e430d5
Autor:
Hande Coskun, Fatima Azzahra Elbahi, Mohammad Al-Mahdi Al-Karagholi, Hashmat Ghanizada, Majid Sheykhzade, Messoud Ashina
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
BackgroundCalcitonin gene-related peptide (CGRP) dilates cranial arteries and triggers headache. The CGRP signaling pathway is partly dependent on activation of ATP-sensitive potassium (KATP) channels. Here, we investigated the effect of the KATP cha
Externí odkaz:
https://doaj.org/article/ad476ca140d44eaf8cc8efa7acf4ac92
Autor:
Jacob C. A. Edvinsson, Karin Warfvinge, Diana N. Krause, Frank W. Blixt, Majid Sheykhzade, Lars Edvinsson, Kristian A. Haanes
Publikováno v:
The Journal of Headache and Pain, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Monoclonal antibodies (mAbs) towards CGRP or the CGRP receptor show good prophylactic antimigraine efficacy. However, their site of action is still elusive. Due to lack of passage of mAbs across the blood-brain barrier the trigemi
Externí odkaz:
https://doaj.org/article/fb0db77b98364d4ea02dfa89ec36cdd2
Autor:
Rasmus Dreier, Ulrik B. Andersen, Julie L. Forman, Majid Sheykhzade, Martin Egfjord, Jørgen L. Jeppesen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 9 (2021)
Background Increased potassium intake lowers blood pressure in patients with hypertension, but increased potassium intake also elevates plasma concentrations of the blood pressure‐raising hormone aldosterone. Besides its well‐described renal effe
Externí odkaz:
https://doaj.org/article/456b81994b4a4a3db5ff7eada00f2cf3
Autor:
Lilliana Beck, Estéfano Pinilla, Daniel Dias Rufino Arcanjo, Raquel Hernanz, Judit Prat-Duran, Asbjørn Graver Petersen, Ralf Köhler, Majid Sheykhzade, Simon Comerma-Steffensen, Ulf Simonsen
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Endothelial cell dysfunction and fibrosis are associated with worsening of the prognosis in patients with cardiovascular disease. Pirfenidone has a direct antifibrotic effect, but vasodilatation may also contribute to the effects of pirfenidone. Ther
Externí odkaz:
https://doaj.org/article/34134b1c93264b05a5e166de31839f1e
Autor:
Lilliana Beck, Junjing Su, Simon Comerma-Steffensen, Estéfano Pinilla, Rune Carlsson, Raquel Hernanz, Majid Sheykhzade, Carl Christian Danielsen, Ulf Simonsen
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Endothelial cell dysfunction and vessel stiffening are associated with a worsened prognosis in diabetic patients with cardiovascular diseases. The present study hypothesized that sex impacts endothelial dysfunction and structural changes in arteries
Externí odkaz:
https://doaj.org/article/8f9bcd1d62d84f4aa8c081719c8906b4
Autor:
Ditte Marie Jensen, Daniel Vest Christophersen, Majid Sheykhzade, Gry Freja Skovsted, Jens Lykkesfeldt, Rasmus Münter, Martin Roursgaard, Steffen Loft, Peter Møller
Publikováno v:
Particle and Fibre Toxicology, Vol 15, Iss 1, Pp 1-18 (2018)
Abstract Background Humans are continuously exposed to particles in the gastrointestinal tract. Exposure may occur directly through ingestion of particles via food or indirectly by removal of inhaled material from the airways by the mucociliary clear
Externí odkaz:
https://doaj.org/article/96e505bacf1c4836adf1d64acdb952dc
Publikováno v:
The Journal of Headache and Pain, Vol 18, Iss 1, Pp 1-9 (2017)
Abstract Background Calcitonin gene-related peptide (CGRP) is one of the most potent endogenous vasodilators identified to date. The present study elucidates the differential interaction of CGRP, its receptor and the effect of the CGRP-receptor antag
Externí odkaz:
https://doaj.org/article/0efe3cc88ff4473f92f40b154194dee4
Autor:
Jing Zhu, Mahdieh Dagina Pedersen, Laraib Sabbah Ahmed, Bahareh Abdolalizadeh, Anne-Sofie Grell, Jais Oliver Berg, Peter Waaben Thulstrup, Henrik Franzyk, Lars Edvinsson, Anette Sams, Majid Sheykhzade, Paul Robert Hansen
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 4, p 1343 (2020)
Human α-calcitonin gene-related peptide (h-α-CGRP) is a highly potent vasodilator peptide that belongs to the family of calcitonin peptides. There are two forms of CGRP receptors in humans and rodents: α-CGRP receptor predominately found in the ca
Externí odkaz:
https://doaj.org/article/2bd44a4ce20b4cfbb3971e9d9df6de42
Autor:
Daniel Vest Christophersen, Nicklas Raun Jacobsen, Ditte Marie Jensen, Ali Kermanizadeh, Majid Sheykhzade, Steffen Loft, Ulla Vogel, Håkan Wallin, Peter Møller
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160731 (2016)
Inflammation and oxidative stress are considered the main drivers of vasomotor dysfunction and progression of atherosclerosis after inhalation of particulate matter. In addition, new studies have shown that particle exposure can induce the level of b
Externí odkaz:
https://doaj.org/article/93b9241eac4e45aa9691bb3022c2b053