Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Majib Jan"'
Autor:
Haibin Xi, Wakana Fujiwara, Karen Gonzalez, Majib Jan, Simone Liebscher, Ben Van Handel, Katja Schenke-Layland, April D. Pyle
Publikováno v:
Cell Reports, Vol 18, Iss 6, Pp 1573-1585 (2017)
Somites form during embryonic development and give rise to unique cell and tissue types, such as skeletal muscles and bones and cartilage of the vertebrae. Using somitogenesis-stage human embryos, we performed transcriptomic profiling of human presom
Externí odkaz:
https://doaj.org/article/2c5d8ad1d37f4e2fa142ed1be03ca66e
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0145280 (2015)
REST (RE1 silencing transcription factor), also known as NRSF (neuron-restrictive silencer factor), is a well-known transcriptional repressor of neural genes in non-neural tissues and stem cells. Dysregulation of REST activity is thought to play a ro
Externí odkaz:
https://doaj.org/article/b0ff6da33e514c5099d259d50c46626b
Autor:
Ben Van Handel, April D. Pyle, Katja Schenke-Layland, Haibin Xi, Wakana Fujiwara, Karen Gonzalez, Simone Liebscher, Majib Jan
Publikováno v:
Cell Reports, Vol 18, Iss 6, Pp 1573-1585 (2017)
Somites form during embryonic development and give rise to unique cell and tissue types, such as skeletal muscles and bones and cartilage of the vertebrae. Using somitogenesis-stage human embryos, we performed transcriptomic profiling of human presom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e5e4113135641649cd19411610b91b
https://doi.org/10.1016/j.celrep.2017.01.040
https://doi.org/10.1016/j.celrep.2017.01.040
Autor:
Majib Jan, Shahab Younesi, Haruko Nakano, Donald B. Kohn, M. Carrie Miceli, Jerome A. Zack, Michael R. Hicks, Chino Kumagai-Cresse, Courtney S. Young, Melissa J. Spencer, April D. Pyle, Derek W. Wang, Atsushi Nakano, Natalia Ermolova, Saravanan Karumbayaram, Stanley F. Nelson
Publikováno v:
Cell Stem Cell. 18:533-540
Mutations in DMD disrupt the reading frame, prevent dystrophin translation, and cause Duchenne muscular dystrophy (DMD). Here we describe a CRISPR/Cas9 platform applicable to 60% of DMD patient mutations. We applied the platform to DMD-derived hiPSCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::549143573ccbae1de1bea1ef1a16490e
https://doi.org/10.1016/j.stem.2016.01.021
https://doi.org/10.1016/j.stem.2016.01.021
Autor:
Jheem D. Medh, Majib Jan
Publikováno v:
Biochemical and Biophysical Research Communications. 462:33-37
In previous studies, we demonstrated that down-regulation of lipoprotein lipase in L6 muscle cells increased insulin-stimulated glucose uptake. In the current study, we used RNA interference technology to silence the LPL gene in L6 cells and generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26601044c59a4b60b6592682bb1b4299
https://doi.org/10.1016/j.bbrc.2015.04.098
https://doi.org/10.1016/j.bbrc.2015.04.098
Autor:
April D. Pyle, Ben Van Handel, Denis Evseenko, Michael R. Hicks, Haibin Xi, Ascia Eskin, Melissa J. Spencer, Stanley F. Nelson, Katrina Paras, Wakana Fujiwara, Majib Jan, Courtney S. Young, Julia Hiserodt
Publikováno v:
Nature cell biology, vol 20, iss 1
Human pluripotent stem cells (hPSCs) can be directed to differentiate into skeletal muscle progenitor cells (SMPCs). However, the myogenicity of hPSC-SMPCs relative to human fetal or adult satellite cells remains unclear. We observed that hPSC-SMPCs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e172ece1c34dae81ff8077469986f5e
https://pubmed.ncbi.nlm.nih.gov/29269948
https://pubmed.ncbi.nlm.nih.gov/29269948
Publikováno v:
PloS one, vol 10, iss 12
PLoS ONE, Vol 10, Iss 12, p e0145280 (2015)
PLoS ONE
PLoS ONE, Vol 10, Iss 12, p e0145280 (2015)
PLoS ONE
REST (RE1 silencing transcription factor), also known as NRSF (neuron-restrictive silencer factor), is a well-known transcriptional repressor of neural genes in non-neural tissues and stem cells. Dysregulation of REST activity is thought to play a ro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca1c83db5c57b4e5678787628af3a7d
https://escholarship.org/uc/item/4ws316tq
https://escholarship.org/uc/item/4ws316tq
Autor:
Majib Jan, April D. Pyle, Atsushi Nakano, Haruko Nakano, Melissa J. Spencer, Courtney S. Young, Michael R. Hicks, M. Carrie Miceli, Shahab Younesi, Stanley F. Nelson, Natalia Ermolova
Publikováno v:
Molecular Therapy. 24:S290
Duchenne muscular dystrophy (DMD) is typically due to frameshifting mutations in the DMD gene encoding dystrophin. Loss of dystrophin protein results in progressive muscle degeneration and premature death. Approximately 60% of DMD patients have frame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0fdc2cf3ef8c699487aac864bf9c3f6c
https://doi.org/10.1016/s1525-0016(16)33543-2
https://doi.org/10.1016/s1525-0016(16)33543-2