Kaempferol Protects Against Cadmium Chloride-Induced Memory Loss and Hippocampal Apoptosis by Increased Intracellular Glutathione Stores and Activation of PTEN/AMPK Induced Inhibition of Akt/mTOR Signaling

Autor: Samy M Eleawa, Mashael Mohammed Bin-Meferij, Majed M. Alshehri, Attalla F. El-kott

Publikováno v: Neurochemical Research. 45:295-309

This study investigated the protective effect of Kaempferol against CdCl2-induced hippocampal damage and memory deficit in rats and investigated if such effects involve modulating the activity of AMPK/PTEN/Akt/mTOR axis. Adult male rats (n = 12/group

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2dfe2fc0c83870478ec25f23143a55b
https://doi.org/10.1007/s11064-019-02911-4

Author response for 'Exendin‐4 protects the hearts of rats from ischemia/reperfusion injury by boosting antioxidant levels and inhibition of JNK/p 66 Shc/NADPH axis'

Autor: Mohamed Samir Ahmed Zaki, Majed M. Alshehri, Ayed A. Shati, Refaat A. Eid, Attalla F. El-kott, Muhammad Alaa Eldeen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1cc9773858e81418a7cf8da0b52d8f84
https://doi.org/10.1111/1440-1681.13299/v2/response1

Chronic consumption of a high-fat diet rich in corn oil activates intrinsic cell death pathway and induces several ultrastructural changes in the atria of healthy and type 1 diabetic rat

Autor: Attalla F. El-kott, Mansour A. Saeed, Mahmoud A. Alkhateeb, Hussain Aldera, Refaat A. Eid, Muhammad Alaa Eldeen, Abd Al‐Rahman Salem Al‐Shudiefat, Samy M Eleawa, Majed M. Alshehri, Mohammed Alassiri, Mubarak Al-Shraim, Mohammad A. Khalil, Mohamed Samir Ahmed Zaki

Publikováno v: Clinical and experimental pharmacologyphysiologyREFERENCES. 46(12)

This study investigates the effect of chronic consumption of a high-fat diet rich in corn oil (CO-HFD) on atrial cells ultrastructure, antioxidant levels and markers of intrinsic cell death of both control and type 1 diabetes mellitus (T1DM)-induced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4cd9f1c3d1b054cfbd2d12da8262846
https://pubmed.ncbi.nlm.nih.gov/31398260

Parathyroid hormone signaling in mature osteoblasts/osteocytes protects mice from age-related bone loss.

Autor: Uda Y; Department of Translational Dental Medicine, Goldman School of Dental Medicine, Boston University, Boston, MA 02118, USA., Saini V; Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Petty CA; Department of Translational Dental Medicine, Goldman School of Dental Medicine, Boston University, Boston, MA 02118, USA., Alshehri M; Department of Translational Dental Medicine, Goldman School of Dental Medicine, Boston University, Boston, MA 02118, USA., Shi C; Department of Translational Dental Medicine, Goldman School of Dental Medicine, Boston University, Boston, MA 02118, USA.; Department of Orthopaedics, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an 710004, Shaanxi Province, P.R. China., Spatz JM; Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.; School of Medicine, University of California San Francisco, San Francisco, CA 94143, USA., Santos R; Department of Translational Dental Medicine, Goldman School of Dental Medicine, Boston University, Boston, MA 02118, USA., Newell CM; Department of Translational Dental Medicine, Goldman School of Dental Medicine, Boston University, Boston, MA 02118, USA., Huang TY; Department of Translational Dental Medicine, Goldman School of Dental Medicine, Boston University, Boston, MA 02118, USA., Kochen A; Department of Translational Dental Medicine, Goldman School of Dental Medicine, Boston University, Boston, MA 02118, USA., Kim JW; Department of Translational Dental Medicine, Goldman School of Dental Medicine, Boston University, Boston, MA 02118, USA., Constantinou CK; Department of Translational Dental Medicine, Goldman School of Dental Medicine, Boston University, Boston, MA 02118, USA., Saito H; Heisenberg-Group for Molecular Skeletal Biology, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany., Held KD; Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA., Hesse E; Heisenberg-Group for Molecular Skeletal Biology, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany., Pajevic PD; Department of Translational Dental Medicine, Goldman School of Dental Medicine, Boston University, Boston, MA 02118, USA.; Endocrine Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

Publikováno v: Aging [Aging (Albany NY)] 2021 Dec 30; Vol. 13 (24), pp. 25607-25642. Date of Electronic Publication: 2021 Dec 30.