Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Maja Hemmings-Mieszczak"'
Autor:
Nania Schärer-Hernández, Diana Dominguez, Johannes Fütterer, Mikhail M. Pooggin, D. Kirk, Lyubov A. Ryabova, S. Corsten, Maja Hemmings-Mieszczak, Thomas Hohn
Publikováno v:
Micron. 32:51-57
In eukaryotes standard initiation of translation involved 40S ribosome scanning to bridge the distance from the cap to the initiation codon. Recently deviations from that rule had been described, including “internal initiation”, “poly-A depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642d9634a198e930c1c8c7a2f7bab031
https://doi.org/10.1016/s0968-4328(00)00020-2
https://doi.org/10.1016/s0968-4328(00)00020-2
Autor:
Thomas Hohn, Maja Hemmings-Mieszczak
Publikováno v:
RNA. 5:1149-1157
The regulation of cauliflower mosaic virus (CaMV) pregenomic 35S RNA translation occurs via nonlinear ribosome migration (ribosome shunt) and is mediated by an elongated hairpin structure in the leader. The replacement of the viral leader by a series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95222e3543fb98ac9f990d3f701356b9
https://doi.org/10.1017/s1355838299990325
https://doi.org/10.1017/s1355838299990325
Publikováno v:
Nucleic Acids Research. 24:619-627
Introns of nuclear pre-mRNAs in dicotyledonous plants, unlike introns in vertebrates or yeast, are distinctly rich in A+U nucleotides and this feature is essential for their processing. In order to define more precisely sequence elements important fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4f11726408f9a883badb485b5b5074c
https://doi.org/10.1093/nar/24.4.619
https://doi.org/10.1093/nar/24.4.619
Autor:
Brian A. Hemmings, Stefaan Wera, Patric Turowski, Regina E. Mayer-Jaekel, Anne Fernandez, Maja Hemmings-Mieszczak, Ned J.C. Lamb
Publikováno v:
Journal of Biological Chemistry. 270:21374-21381
Efficient translation of the mRNA encoding the 65-kDa regulatory subunit (PR65 alpha) of protein phosphatase 2A (PP2A) is prevented by an out of frame upstream AUG and a stable stem-loop structure (delta G = -55.9 kcal/mol) in the 5'-untranslated reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc29b81e9a3ea10d94c0421d6909be23
https://doi.org/10.1074/jbc.270.36.21374
https://doi.org/10.1074/jbc.270.36.21374
Publikováno v:
Plant Molecular Biology. 28:569-574
We have previously characterized nuclear cDNA clones encoding two RNA binding proteins, CP-RBP30 and CP-RBP-31, which are targeted to chloroplasts in Nicotiana plumbaginifolia. In this report we describe the analysis of the 3'-untranslated regions (3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f563f34a668b59be85c0e4c613ff72
https://doi.org/10.1007/bf00020402
https://doi.org/10.1007/bf00020402
Autor:
Bettina Dummler, Brian A. Hemmings, Zhong Zhou Yang, Thomas Michaelis, Daniela Brodbeck, Jens Frahm, Takashi Watanabe, Oliver Tschopp, Maja Hemmings-Mieszczak
Publikováno v:
Development (Cambridge, England). 132(13)
Protein kinase B is implicated in many crucial cellular processes, such as metabolism, apoptosis and cell proliferation. In contrast to Pkb(alpha) and Pkb(beta)-deficient mice, Pkb(gamma)(-/-) mice are viable, show no growth retardation and display n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20fe491a424c138127ef2bd7110512a5
https://pubmed.ncbi.nlm.nih.gov/15930105
https://pubmed.ncbi.nlm.nih.gov/15930105
Autor:
Zhong-Zhou Yang, Jianhua Feng, Daniela Brodbeck, Oliver Tschopp, Maja Hemmings-Mieszczak, Brian A. Hemmings, Elias Perentes
Publikováno v:
The Journal of biological chemistry. 278(34)
Protein kinase B alpha (PKB alpha/Akt1) is implicated in the regulation of metabolism, transcription, cell survival, angiogenesis, cell migration, growth, and tumorigenesis. Previously, it was reported that PKB alpha-deficient mice are small with inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a71345e60bff89e82f0f6f27b795bc9
https://pubmed.ncbi.nlm.nih.gov/12783884
https://pubmed.ncbi.nlm.nih.gov/12783884
Autor:
Maja Hemmings-Mieszczak, Gabriele Dorn, William Leonard Wishart, Francois Natt, Jonathan Hall
Synthetic 21-bp-long short interfering RNAs (siRNA) can stimulate sequence-specific mRNA degradation in mammalian cell cultures, a process referred to as RNA interference (RNAi). In the present study, the potential of RNAi was compared to the traditi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e402c6eb985f5237a1c9dfaea5d02cc0
https://europepmc.org/articles/PMC153750/
https://europepmc.org/articles/PMC153750/
Publikováno v:
Genesdevelopment. 16(20)
Hereditary cancers have revealed the existence of a number of tumor suppressor genes that function to control cell proliferation and maintain normal tissue homeostasis (Macleod 2000). Two tumor suppressors have been implicated in the PI3K-signaling p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26898fb21604fee4ec59a66a0022803
https://pubmed.ncbi.nlm.nih.gov/12381661
https://pubmed.ncbi.nlm.nih.gov/12381661
Autor:
Maja Hemmings-Mieszczak, Ulrich Klahre, D A Wieczorek Kirk, Witold Filipowicz, Zdravko J. Lorković
Publikováno v:
RNA (New York, N.Y.). 6(11)
Introns in plant nuclear pre-mRNAs are highly enriched in U or U + A residues and this property is essential for efficient splicing. Moreover, 3'-untranslated regions (3'-UTRs) in plant pre-mRNAs are generally UA-rich and contain sequences that are i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5588c7d8d75f1d0a99fdd5262c6761e5
https://pubmed.ncbi.nlm.nih.gov/11105760
https://pubmed.ncbi.nlm.nih.gov/11105760