Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Maja Etzel"'
Publikováno v:
Sensors, Vol 17, Iss 9, p 1990 (2017)
RNA aptamers readily recognize small organic molecules, polypeptides, as well as other nucleic acids in a highly specific manner. Many such aptamers have evolved as parts of regulatory systems in nature. Experimental selection techniques such as SELE
Externí odkaz:
https://doaj.org/article/2cf4c4f8f8894591a0126c4816bfa464
Publikováno v:
Nucleic Acids Research
We describe a synthetic riboswitch element that implements a regulatory principle which directly addresses an essential tRNA maturation step. Constructed using a rational in silico design approach, this riboswitch regulates RNase P-catalyzed tRNA 5
Autor:
Robert, Serfling, Christian, Lorenz, Maja, Etzel, Gerda, Schicht, Thore, Böttke, Mario, Mörl, Irene, Coin
Publikováno v:
Nucleic Acids Research
The pyrrolysyl-tRNA synthetase/tRNAPyl pair is the most versatile and widespread system for the incorporation of non-canonical amino acids (ncAAs) into proteins in mammalian cells. However, low yields of ncAA incorporation severely limit its applicab
Autor:
Maja Etzel, Mario Mörl
Publikováno v:
Biochemistry. 56(9)
In synthetic biology, metabolic engineering, and gene therapy, there is a strong demand for orthogonal or externally controlled regulation of gene expression. Here, RNA-based regulatory devices represent a promising emerging alternative to proteins,