Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Maja Bućan"'
Autor:
Kelly Finke, Michael Kourakos, Gabriela Brown, Huyen Trang Dang, Shi Jie Samuel Tan, Yuval B Simons, Shweta Ramdas, Alejandro A Schäffer, Rachel L Kember, Maja Bućan, Sara Mathieson
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 2, p e1008638 (2021)
In this work we develop a novel algorithm for reconstructing the genomes of ancestral individuals, given genotype or sequence data from contemporary individuals and an extended pedigree of family relationships. A pedigree with complete genomes for ev
Externí odkaz:
https://doaj.org/article/d24f8ecd506c42678b641f010b0c029d
Autor:
Stacey D. Elkhatib Smidt, Arpita Ghorai, Sara C. Taylor, Brielle N. Gehringer, Holly C. Dow, Allison Langer, Eric Rawot, Jing Zhang, Jonathan A. Mitchell, Daniel J. Rader, Laura Almasy, Edward S. Brodkin, Maja Bućan
Publikováno v:
Autism Research. 15:641-652
Autistic children and adults often have sleep disturbances, which may affect their and their family's quality of life. Yet, the relationship between sleep-wake patterns and autism spectrum traits is understudied. Identifying such relationships could
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e28de83e22a2dec9367c9fe4dc923f8
https://doi.org/10.1002/aur.2660
https://doi.org/10.1002/aur.2660
Autor:
Moe Nakanishi, Jun Nomura, Xiao Ji, Kota Tamada, Takashi Arai, Eiki Takahashi, Maja Bućan, Toru Takumi
Publikováno v:
PLoS Genetics, Vol 13, Iss 10, p e1007035 (2017)
[This corrects the article DOI: 10.1371/journal.pgen.1006940.].
Externí odkaz:
https://doaj.org/article/beb153ad20ce48a98103afadcff117fc
Autor:
Moe Nakanishi, Jun Nomura, Xiao Ji, Kota Tamada, Takashi Arai, Eiki Takahashi, Maja Bućan, Toru Takumi
Publikováno v:
PLoS Genetics, Vol 13, Iss 8, p e1006940 (2017)
Genetic mutations contribute to the etiology of autism spectrum disorder (ASD), a common, heterogeneous neurodevelopmental disorder characterized by impairments in social interaction, communication, and repetitive and restricted patterns of behavior.
Externí odkaz:
https://doaj.org/article/83b4b53600b84d8bae32a1bf0db7b363
Autor:
Benjamin Georgi, David Craig, Rachel L Kember, Wencheng Liu, Ingrid Lindquist, Sara Nasser, Christopher Brown, Janice A Egeland, Steven M Paul, Maja Bućan
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004229 (2014)
Bipolar disorder is a common, heritable mental illness characterized by recurrent episodes of mania and depression. Despite considerable effort to elucidate the genetic underpinnings of bipolar disorder, causative genetic risk factors remain elusive.
Externí odkaz:
https://doaj.org/article/1345e3e98470465ea318e2173d590b88
Publikováno v:
PLoS Genetics, Vol 9, Iss 5, p e1003484 (2013)
Understanding the core set of genes that are necessary for basic developmental functions is one of the central goals in biology. Studies in model organisms identified a significant fraction of essential genes through the analysis of null-mutations th
Externí odkaz:
https://doaj.org/article/58419f0b9fc74c90b04503a579f891e1
Autor:
Rachel L. Kember, Alison K. Merikangas, Shefali S. Verma, Anurag Verma, Renae Judy, Scott M. Damrauer, Marylyn D. Ritchie, Daniel J. Rader, Maja Bućan, Goncalo Abecasis, Aris Baras, Michael Cantor, Giovanni Coppola, Aris Economides, Luca Lotta, John D. Overton, Jeffrey G. Reid, Alan Shuldiner, Christina Beechert, Caitlin Forsythe, Erin D. Fuller, Zhenhua Gu, Michael Lattari, Alexander Lopez, Thomas D. Schleicher, Maria Sotiropoulos Padilla, Karina Toledo, Louis Widom, Sarah E. Wolf, Manasi Pradhan, Kia Manoochehri, Ricardo H. Ulloa, Xiaodong Bai, Suganthi Balasubramanian, Leland Barnard, Andrew Blumenfeld, Gisu Eom, Lukas Habegger, Young Hahn, Alicia Hawes, Shareef Khalid, Evan K. Maxwell, William Salerno, Jeffrey C. Staples, Ashish Yadav, Marcus B. Jones, Lyndon J. Mitnaul
Publikováno v:
Biol Psychiatry
Background Prediction of disease risk is a key component of precision medicine. Common traits such as psychiatric disorders have a complex polygenic architecture, making the identification of a single risk predictor difficult. Polygenic risk scores (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcae4d9b81d3bbf0536f99f86413b7f7
https://pubmed.ncbi.nlm.nih.gov/32919613
https://pubmed.ncbi.nlm.nih.gov/32919613
Autor:
Mary E, Dickinson, Ann M, Flenniken, Xiao, Ji, Lydia, Teboul, Michael D, Wong, Jacqueline K, White, Terrence F, Meehan, Wolfgang J, Weninger, Henrik, Westerberg, Hibret, Adissu, Candice N, Baker, Lynette, Bower, James M, Brown, L Brianna, Caddle, Francesco, Chiani, Dave, Clary, James, Cleak, Mark J, Daly, James M, Denegre, Brendan, Doe, Mary E, Dolan, Sarah M, Edie Helmut Fuchs, Valerie, Gailus-Durner, Antonella, Galli, Alessia, Gambadoro, Juan, Gallegos, Shiying, Guo, Neil R, Horner, Chih-Wei, Hsu, Sara J, Johnson, Sowmya, Kalaga, Lance C, Keith, Louise, Lanoue, Thomas N, Lawson, Monkol, Lek, Manuel, Mark, Susan, Marschall, Jeremy, Mason, Melissa L, McElwee, Susan Newbigging Lauryl M J, Nutter, Kevin A, Peterson, Ramiro, Ramirez-Solis, Douglas J, Rowland, Edward, Ryder, Kaitlin E, Samocha, John R, Seavitt, Mohammed, Selloum, Zsombor, Szoke-Kovacs, Masaru, Tamura, Amanda G, Trainor, Ilinca, Tudose, Shigeharu, Wakana, Jonathan, Warren, Olivia, Wendling, David B, West, Leeyean, Wong, Atsushi, Yoshiki, Wolfgang, Wurst, Daniel G, MacArthur, Glauco P, Tocchini-Valentini, Xiang, Gao, Paul, Flicek, Allan, Bradley, William C, Skarnes, Monica J, Justice, Helen E, Parkinson, Mark, Moore, Sara, Wells, Robert E, Braun, Karen L, Svenson, Martin Hrabe, de Angelis, Yann, Herault, Tim, Mohun, Ann-Marie, Mallon, R Mark, Henkelman, Steve D M, Brown, David J, Adams, K C Kent, Lloyd, Colin, McKerlie, Arthur L, Beaudet, Maja Bućan Stephen A, Murray
Publikováno v:
Nature
Approximately one third of all mammalian genes are essential for life. Phenotypes resulting from mouse knockouts of these genes have provided tremendous insight into gene function and congenital disorders. As part of the International Mouse Phenotypi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::74b5a3945655035b12ce6c274bdc013b
https://pubmed.ncbi.nlm.nih.gov/27626380
https://pubmed.ncbi.nlm.nih.gov/27626380
Autor:
Dickinson, Mary E, Flenniken, Ann M, Ji, Xiao, Teboul, Lydia, Wong, Michael D, White, Jacqueline K, Meehan, Terrence F, Weninger, Wolfgang J, Westerberg, Henrik, Adissu, Hibret, Baker, Candice N, Bower, Lynette, Brown, James M, Caddle, L Brianna, Chiani, Francesco, Clary, Dave, Cleak, James, Daly, Mark J, Denegre, James M, Doe, Brendan, Dolan, Mary E, Edie Helmut Fuchs, Sarah M, Gailus-Durner, Valerie, Galli, Antonella, Gambadoro, Alessia, Gallegos, Juan, Guo, Shiying, Horner, Neil R, Hsu, Chih-Wei, Johnson, Sara J, Kalaga, Sowmya, Keith, Lance C, Lanoue, Louise, Lawson, Thomas N, Lek, Monkol, Mark, Manuel, Marschall, Susan, Mason, Jeremy, McElwee, Melissa L, Nutter, Susan Newbigging Lauryl MJ, Peterson, Kevin A, Ramirez-Solis, Ramiro, Rowland, Douglas J, Ryder, Edward, Samocha, Kaitlin E, Seavitt, John R, Selloum, Mohammed, Szoke-Kovacs, Zsombor, Tamura, Masaru, Trainor, Amanda G, Tudose, Ilinca, Wakana, Shigeharu, Warren, Jonathan, Wendling, Olivia, West, David B, Wong, Leeyean, Yoshiki, Atsushi, International Mouse Phenotyping Consortium, Wurst, Wolfgang, MacArthur, Daniel G, Tocchini-Valentini, Glauco P, Gao, Xiang, Flicek, Paul, Bradley, Allan, Skarnes, William C, Justice, Monica J, Parkinson, Helen E, Moore, Mark, Wells, Sara, Braun, Robert E, Svenson, Karen L, de Angelis, Martin Hrabe, Herault, Yann, Mohun, Tim, Mallon, Ann-Marie, Henkelman, R Mark, Brown, Steve DM, Adams, David J, Lloyd, KC Kent, McKerlie, Colin, Beaudet, Arthur L, Murray, Maja Bućan Stephen A
Publikováno v:
Nature, vol 551, iss 7680
This corrects the article DOI: 10.1038/nature19356.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::32fcd8b4adc5cb08e911c01c01c8f19b
https://escholarship.org/uc/item/21m2349q
https://escholarship.org/uc/item/21m2349q
Autor:
Steve D.M. Brown, L. Brianna Caddle, Valerie Gailus-Durner, Xiao Ji, Sowmya Kalaga, Mark J. Daly, Kevin C K Lloyd, Susan Newbigging Lauryl M. J. Nutter, Jeremy Mason, Martin Hrabé de Angelis, Ann-Marie Mallon, Helen Parkinson, Paul Flicek, Timothy J. Mohun, Lynette Bower, Shiying Guo, Edward Ryder, Ramiro Ramirez-Solis, Ilinca Tudose, William C. Skarnes, Hibret A. Adissu, Francesco Chiani, Lance C. Keith, Maja Bućan Stephen A. Murray, Susan Marschall, John R. Seavitt, Henrik Westerberg, Chih-Wei Hsu, Terrence F. Meehan, David B. West, Ann M. Flenniken, Mohammed Selloum, Karen L. Svenson, Daniel G. MacArthur, Allan Bradley, Zsombor Szoke-Kovacs, Alessia Gambadoro, Glauco P. Tocchini-Valentini, James M. Denegre, Leeyean Wong, Neil R. Horner, Amanda G. Trainor, Mary E. Dickinson, James M. Brown, Shigeharu Wakana, Kevin A. Peterson, Lydia Teboul, Michael D. Wong, Atsushi Yoshiki, Robert Braun, Mark W. Moore, Masaru Tamura, Jacqueline K. White, Mary E. Dolan, Manuel Mark, David J. Adams, Kaitlin E. Samocha, Thomas N. Lawson, Monica J. Justice, Candice N. Baker, Wolfgang Weninger, Melissa L. McElwee, Sara Wells, Olivia Wendling, Douglas J. Rowland, R. Mark Henkelman, Juan Gallegos, Sara Johnson, Colin McKerlie, Wolfgang Wurst, Dave Clary, Xiang Gao, Louise Lanoue, Monkol Lek, Sarah M. Edie Helmut Fuchs, Jonathan Warren, Yann Herault, Arthur L. Beaudet, James Cleak, Brendan Doe, Antonella Galli
Publikováno v:
Nature. 551:398-398
Nature 537, 508–514 (2016); doi:10.1038/nature19356 In this Article, the author Wolfgang Wurst was erroneously omitted from the author list. They are associated with the affiliations: HelmholtzZentrum Munich, Institute of Developmental Genetics, 85
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b46803bbeb55e18795e064aa6cfb1c3
https://doi.org/10.1038/nature24643
https://doi.org/10.1038/nature24643