Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Maja Šolman"'
Autor:
Maja Šolman, Alessio Ligabue, Olga Blaževitš, Alok Jaiswal, Yong Zhou, Hong Liang, Benoit Lectez, Kari Kopra, Camilo Guzmán, Harri Härmä, John F Hancock, Tero Aittokallio, Daniel Abankwa
Publikováno v:
eLife, Vol 4 (2015)
Hotspot mutations of Ras drive cell transformation and tumorigenesis. Less frequent mutations in Ras are poorly characterized for their oncogenic potential. Yet insight into their mechanism of action may point to novel opportunities to target Ras. He
Externí odkaz:
https://doaj.org/article/a84df42c6ba14fc0a17e36dc361c148f
Publikováno v:
PLoS ONE, Vol 9, Iss 1 (2014)
Externí odkaz:
https://doaj.org/article/f9764661da97459abe091a943bdaea06
Autor:
Bernd Thiede, Frauke Zipp, Daniel Abankwa, Krishnaraj Rajalingam, Stefan Tenzer, Hajime Yurugi, Katharina Schulenburg, Tobias Bopp, Alexander Ulges, Maja Šolman, Ulrike Buehler
Publikováno v:
The EMBO journal. 37(16)
T helper (Th)17 cells represent a unique subset of CD4(+) T cells and are vital for clearance of extracellular pathogens including bacteria and fungi. However, Th17 cells are also involved in orchestrating autoimmunity. By employing quantitative surf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f3e0a3bdc56a0e2ecacc2c35c88638b
https://pubmed.ncbi.nlm.nih.gov/30049713
https://pubmed.ncbi.nlm.nih.gov/30049713
Autor:
Luc Reymond, Daniel Abankwa, Debora M. Andrade, Camilo Guzmán, Maja Šolman, Christian Eggeling, Olga Blaževitš, Alessio Ligabue
Publikováno v:
The Journal of Biological Chemistry
Background: Ras nanoclusters contain 6-8 Ras proteins on the plasma membrane and serve as indispensable signaling platforms for Ras-MAPK signaling. Results: Ras membrane conformer mutants impart specific galectin-1-dependent nanoclustering responses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6aeef3fde9bcee1721f24958d5a90ac
https://ora.ox.ac.uk/objects/uuid:2ae79b1b-15e4-4d28-9354-deda5807c285
https://ora.ox.ac.uk/objects/uuid:2ae79b1b-15e4-4d28-9354-deda5807c285
Autor:
Maja Šolman, Anastassios C. Papageorgiou, Daniel Abankwa, Nicholas Ariotti, Olga Blaževitš, Alfred Wittinghofer, Yonatan G. Mideksa, Hossein Nakhaeizadeh, Alessio Ligabue, Eyad K. Fansa, Mohammad Reza Ahmadian
Publikováno v:
Scientific Reports
Galectin-1 (Gal-1) dimers crosslink carbohydrates on cell surface receptors. Carbohydrate-derived inhibitors have been developed for cancer treatment. Intracellularly, Gal-1 was suggested to interact with the farnesylated C-terminus of Ras thus speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa982875d6877ce5fdc7caf0ea73b4aa
http://juuli.fi/Record/0274950516
http://juuli.fi/Record/0274950516
Autor:
Olga Blaževitš, Benoit Lectez, Daniel Abankwa, Camilo Guzmán, Tero Aittokallio, Alok Jaiswal, Yong Zhou, Maja Šolman, Alessio Ligabue, Kari Kopra, Harri Härmä, Hong Liang, John F. Hancock
Publikováno v:
eLife, Vol 4 (2015)
eLife
eLife
Hotspot mutations of Ras drive cell transformation and tumorigenesis. Less frequent mutations in Ras are poorly characterized for their oncogenic potential. Yet insight into their mechanism of action may point to novel opportunities to target Ras. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d9bc1eaa1ad8fd706728d0df1b38499
https://doi.org/10.7554/elife.08905
https://doi.org/10.7554/elife.08905
Autor:
Alessio Ligabue, Yong Zhou, Hong Liang, Alok Jaiswal, John F. Hancock, Olga Blaževitš, Harri Härmä, Maja Šolman, Kari Kopra, Camilo Guzmán, Tero Aittokallio, Benoit Lectez, Daniel Abankwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f733995c9d788483988d793c6afa324
https://doi.org/10.7554/elife.08905.020
https://doi.org/10.7554/elife.08905.020
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 1 (2014)
PLoS ONE, Vol 9, Iss 1 (2014)
The first seven bars in the bar graph of Figure 4 were erroneously altered. Please see the corrected Figure 4 here: http://plosone.org/corrections/pone.0066425.g004.cn.tif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de481c644deb3dd299ce45ca647eb8b
https://doi.org/10.1371/annotation/98f18cba-53d7-43a5-9f23-4c35d0fd4ce1
https://doi.org/10.1371/annotation/98f18cba-53d7-43a5-9f23-4c35d0fd4ce1
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66425 (2013)
PLoS ONE
PLoS ONE
Hundreds of eukaryotic signaling proteins require myristoylation to functionally associate with intracellular membranes. N-myristoyl transferases (NMT) responsible for this modification are established drug targets in cancer and infectious diseases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24ea0413af6418c905a3972f4143012e
http://europepmc.org/articles/PMC3688908?pdf=render
http://europepmc.org/articles/PMC3688908?pdf=render
Publikováno v:
Biophysical Journal. 104:119a
Members of Ras family of proteins are central regulators of crucial cellular processes. Their deregulation is associated with severe diseases, such as cancer and neuro-cardio-facio-cutaneous syndromes. Ras isoforms are very similar in structure, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd027b7383cfc28d358f1724aa8915f1
https://doi.org/10.1016/j.bpj.2012.11.687
https://doi.org/10.1016/j.bpj.2012.11.687