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pro vyhledávání: '"Maj Simonsen"'
Akademický článek
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Autor:
de Lázaro, Irene, Bussy, Cyrill, Yilmazer, Açelya, Jackson, Maj Simonsen, Humphreys, Neil E., Kostarelos, Kostas
Publikováno v:
In Biomaterials September 2014 35(29):8312-8320
Autor:
Neil E. Humphreys, Werner Müller, Emmanuel Pinteaux, Ari Waisman, Ilgiz A. Mufazalov, Wesam H. Abdulaal, Sheila E. Francis, Maj Simonsen-Jackson
Publikováno v:
Pinteaux, E, Abdulaal, W H, Mufazalov, I A, Humphreys, N E, Simonsen-Jackson, M, Francis, S, Müller, W & Waisman, A 2020, ' Cell-specific conditional deletion of interleukin-1 (IL-1) ligands and its receptors: a new toolbox to study the role of IL-1 in health and disease ', Journal of Molecular Medicine, vol. 98, no. 7, pp. 923-930 . https://doi.org/10.1007/s00109-020-01928-5
Journal of Molecular Medicine (Berlin, Germany)
Journal of Molecular Medicine (Berlin, Germany)
The pro-inflammatory cytokine interleukin-1 (IL-1) plays a key role in many physiological processes and during the inflammatory and immune response to most common diseases. IL-1 exists as two agonists, IL-1α and IL-1β that bind to the only signalin
Autor:
Bageghni, Sumia A., Hemmings, Karen E., Yuldasheva, Nadira Y., Maqbool, Azhar, Gamboa-Esteves, Filomena O., Humphreys, Neil E., Jackson, Maj Simonsen, Denton, Christopher P., Francis, Sheila, Porter, Karen E., Ainscough, Justin F.X., Pinteaux, Emmanuel, Drinkhill, Mark J., Turner, Neil A.
Publikováno v:
JCI Insight
It has been hypothesized that IL-1α is released from damaged cardiomyocytes following myocardial infarction (MI) and activates cardiac fibroblasts via its receptor (IL-1R1) to drive the early stages of cardiac remodeling. This study aimed to definit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::80c33524bf2e36a8067fcf5ba4cfd04c
https://eprints.whiterose.ac.uk/149893/8/125074.2-20190830133803-covered-253bed37ca4c1ab43d105aefdf7b5536.pdf
https://eprints.whiterose.ac.uk/149893/8/125074.2-20190830133803-covered-253bed37ca4c1ab43d105aefdf7b5536.pdf
Publikováno v:
Joyce, W, Simonsen, M, Gesser, H & Wang, T 2016, ' The effects of hypoxic bradycardia and extracellular HCO3-/CO2 on hypoxic performance in the eel heart ', The Journal of Experimental Biology, vol. 219, no. 3, pp. 302-305 . https://doi.org/10.1242/jeb.130971
During hypoxia, fishes exhibit a characteristic hypoxic bradycardia, the functional significance of which remains debated. Here, we investigated the hypothesis that hypoxic bradycardia primarily safeguards cardiac performance. In preparations from th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::686ac44bacd4893672d36d93f8e79641
https://pure.au.dk/portal/da/publications/the-effects-of-hypoxic-bradycardia-and-extracellular-hco3co2-on-hypoxic-performance-in-the-eel-heart(81bd1928-6bee-4a2d-8380-8740f5e8d5c6).html
https://pure.au.dk/portal/da/publications/the-effects-of-hypoxic-bradycardia-and-extracellular-hco3co2-on-hypoxic-performance-in-the-eel-heart(81bd1928-6bee-4a2d-8380-8740f5e8d5c6).html
Autor:
Neil E. Humphreys, Maj Simonsen Jackson, Irene de Lázaro, Cyrill Bussy, Açelya Yilmazer, Kostas Kostarelos
Publikováno v:
Biomaterials. 35(29)
The in vivo cell reprogramming of terminally differentiated somatic cells to a pluripotent state by the ectopic expression of defined transcription factors has been previously shown in the BALB/c mouse liver upon plasmid DNA injection with no teratom
Akademický článek
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Autor:
Preece C; Wellcome Centre for Human Genetics, Oxford, UK., Biggs D; Wellcome Centre for Human Genetics, Oxford, UK., Grencis E; University of Manchester, Manchester, UK., Jackson MS; University of Manchester, Manchester, UK., Allen S; Mary Lyon Centre at MRC Harwell, Didcot, UK., Fray M; Mary Lyon Centre at MRC Harwell, Didcot, UK., Adamson A; University of Manchester, Manchester, UK., Davies B; Wellcome Centre for Human Genetics, Oxford, UK. ben.davies@crick.ac.uk.; The Francis Crick Institute, London, UK. ben.davies@crick.ac.uk.
Publikováno v:
Lab animal [Lab Anim (NY)] 2024 Jul; Vol. 53 (7), pp. 181-185. Date of Electronic Publication: 2024 Jun 17.
Autor:
Bageghni SA; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom., Hemmings KE; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom., Yuldasheva NY; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom., Maqbool A; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom., Gamboa-Esteves FO; Leeds Institute of Cancer and Pathology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom., Humphreys NE; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom., Jackson MS; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom., Denton CP; Institute of Immunity and Transplantation, Centre for Rheumatology and Connective Tissue Diseases, University College London and Royal Free Hospital, London, United Kingdom., Francis S; Department of Infection, Immunity & Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, United Kingdom., Porter KE; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom., Ainscough JF; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom., Pinteaux E; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom., Drinkhill MJ; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom., Turner NA; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom.
Publikováno v:
JCI insight [JCI Insight] 2019 Aug 08; Vol. 5. Date of Electronic Publication: 2019 Aug 08.