Direct synthesis of functionalized 3-pyrrolidines and 4-piperidines using the borrowing hydrogen methodology

Autor: Malvina Larduinat, Jordan François, Maiwenn Jacolot, Florence Popowycz

The Ir(III)-catalyzed synthesis of 3-pyrrolidinols and 4-piperidinols combining 1,2,4-butanetriol or 1,3,5-pentanetriol with primary amines was carried out. This borrowing hydrogen methodology (BH) was further extended to the sequential diamination o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8dfa27510a2e8f90ad3552ef9053b4fa
https://doi.org/10.26434/chemrxiv-2023-ctmh2

Synthesis of stachybotrin C and all of its stereoisomers: structure revision

Autor: Mickael Jean, Naresh Tumma, Arnaud Bondon, Maiwenn Jacolot, Srivari Chandrasekhar, Pierre van de Weghe

Publikováno v: Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2013, 78 (14), pp.7169-75. ⟨10.1021/jo401116r⟩
Journal of Organic Chemistry, 2013, 78 (14), pp.7169-75. ⟨10.1021/jo401116r⟩

International audience; We disclose the first total synthesis of stachybotrin C, a potent neuroprotective natural compound. All of the four stereoisomers have been prepared and fully characterized with the aim to attribute the absolute configuration

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcfa84adcf70ba7ea1d819ed4bf7b9ee
https://hal-univ-rennes1.archives-ouvertes.fr/hal-00862776

The Prins Reaction Using Ketones: Rationalization and Application toward the Synthesis of the Portentol Skeleton.

Autor: Maiwenn Jacolot, Mickael Jean, Nicolas Levoin, Pierre van de Weghe

Publikováno v: Organic Letters; Jan2012, Vol. 14 Issue 1, p58-61, 4p