Effect of allopurinol in addition to hypothermia treatment in neonates for hypoxic-ischemic brain injury on neurocognitive outcome (ALBINO): study protocol of a blinded randomized placebo-controlled parallel group multicenter trial for superiority (phase III)

Autor: Benders, MJNL, Klebermass-Schrehof, K, Metsaranta, M, Rudiger, M, Poets, CF, Benders, M, Allegaert, K, Naulaers, G, Guimaraes, H, Stiris, T, Vanhatalo, S, Metsvaht, T, Engel, C, Maiwald, CA, von Oldershausen, G, Bergmann, I, Weiss, M, Wichera, CJBR, Eichhorn, A, Raubuch, M, Schuler, B, van Veldhuizen, CKW, Lameris, B, Jacobs, Y, van der Vlught-Meijer, R, Kliniken, T, Griesmaier, E, Salzburg, U, Brandner, J, Tackoen, M, Reibel, R, Cornette, L, Viellevoye, LR, Saik, P, Kaar, R, Andresson, P, Franz, AR, Carus, CG, Winkler, S, Hoehn, T, Teig, N, Schroth, M, Fusch, C, Thome, UH, Ehrhardt, H, Cattarossi, L, Mauro, I, Baraldi, E, Carnielli, V, Paterlini, MG, Napolitano, M, Faldini, F, Lista, GL, Barbarini, M, Pagani, L, Anna, S, Mastretta, E, Vento, G, Fumagalli, MM, Binotti, NM, van Weissenbruch, MM, van Straaten, HLM, Annink, KV, van Bel, F, Dudink, J, Derks, JB, de Boer, IP, Meijssen, CB, de Haan, TR, van Rooij, LG, van Hillegersberg, JL, van Dongen, M, Dassel, ACM, Dijkman, KP, van Houten, MA, van der Schoor, SRD, Nestaas, E, Mazela, J, Karpinski, L, Vilan, AI, de Pinho, LF, Ferraz, C, Pereira, A, Barroso, R, da Graca, M, Tome, T, Pinto, F, Vento, M, Rodilla, JM, Luz, M, Pico, C, Camprubi, MC, Suazo, JAH, Valverde, E, Lorenzo, JRF, Orgado, JM, Boix, H, Parrilla, FJ, Blanco, D, Moral-Pumarega, MT, Bassler, D, Maletzki, J, Knoepfli, C, Hagmann, C, Kleber, M, Schulzke, S, Stocker, M, Birkenmaier, A, Riedel, T, ALBINO Study Grp

Publikováno v: BMC PEDIATRICS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
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BackgroundPerinatal asphyxia and resulting hypoxic-ischemic encephalopathy is a major cause of death and long-term disability in term born neonates. Up to 20,000 infants each year are affected by HIE in Europe and even more in regions with lower leve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::93b4a8fa7524c7f697947c7507bb5e52
https://fundanet.iislafe.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=10700

Response to: 'Randomised crossover study on pulse oximeter readings from different sensors in very preterm infants' by Sharma et al .

Autor: Maiwald CA; Department of Neonatology, University Hospital Tübingen, Tübingen, Germany.; Center for Pediatric Clinical Studies (CPCS), University Hospital Tübingen, Tübingen, Germany., Schwarz CE; Department of Neonatology, Center for Pediatric and Adolescent Medicine, University Hospital Heidelberg, Heidelberg, Germany., Böckmann K; Department of Neonatology, University Hospital Tübingen, Tübingen, Germany., Springer L; Department of Neonatology, University Hospital Tübingen, Tübingen, Germany., Poets CF; Department of Neonatology, University Hospital Tübingen, Tübingen, Germany christian-f.poets@med.uni-tuebingen.de., Franz AR; Department of Neonatology, University Hospital Tübingen, Tübingen, Germany.; Center for Pediatric Clinical Studies (CPCS), University Hospital Tübingen, Tübingen, Germany.

Publikováno v: Archives of disease in childhood. Fetal and neonatal edition [Arch Dis Child Fetal Neonatal Ed] 2024 Nov 01. Date of Electronic Publication: 2024 Nov 01.

Less Invasive Surfactant Administration in Preterm Infants in Tertiary Neonatal Intensive Care Units in Germany: A Survey.

Autor: Maiwald CA; Department of Neonatology, University Children's Hospital Tübingen, Tübingen, Germany.; Center for Pediatric Clinical Studies (CPCS), University Hospital Tübingen, Tübingen, Germany., Franz AR; Department of Neonatology, University Children's Hospital Tübingen, Tübingen, Germany.; Center for Pediatric Clinical Studies (CPCS), University Hospital Tübingen, Tübingen, Germany., Poets CF; Department of Neonatology, University Children's Hospital Tübingen, Tübingen, Germany., Springer L; Department of Neonatology, University Children's Hospital Tübingen, Tübingen, Germany.

Publikováno v: Neonatology [Neonatology] 2024 Jul 17, pp. 1-10. Date of Electronic Publication: 2024 Jul 17.

Parental perspectives about information and deferred versus two-stage consent in studies of neonatal asphyxia.

Autor: Maiwald CA; Department of Neonatology, University Children's Hospital Tübingen, Tübingen, Baden-Württemberg, Germany Christian.Maiwald@med.uni-tuebingen.de.; Center for Pediatric Clinical Studies (CPCS), University Hospital Tübingen, Tübingen, Baden-Württemberg, Germany., Rovers C; Department of Neonatology, University Children's Hospital Tübingen, Tübingen, Baden-Württemberg, Germany., Janvier A; Department of Pediatrics, Bureau de l'Éthique Clinique, Université de Montréal, Montreal, Québec, Canada.; Division of Neonatology, Research Center, Clinical Ethics Unit, Palliative Care Unit, Unité de recherche en éthique clinique et partenariat famille, CHU Sainte-Justine, Montreal, Québec, Canada., Sturm H; Centre for Public Health and Health Services Research, Faculty of Medicine, University Hospital Tübingen, Tübingen, Baden-Württemberg, Germany., Michaelis M; Centre for Public Health and Health Services Research, Faculty of Medicine, University Hospital Tübingen, Tübingen, Baden-Württemberg, Germany.; Institute of Occupational and Social Medicine and Health Services Research, University Hospital Tübingen, Tübingen, Baden-Württemberg, Germany., Marckmann G; Institute of Ethics, History and Theory of Medicine, Ludwig Maximilians University (LMU) Munich, Munich, Bayern, Germany., Ehni HJ; Institute for Ethics and History of Medicine, Medical Faculty, University of Tübingen, Tübingen, Baden-Württemberg, Germany., Poets CF; Department of Neonatology, University Children's Hospital Tübingen, Tübingen, Baden-Württemberg, Germany., Rüdiger M; Clinic for Pediatrics, Department of Neonatology and Pediatric Intensive Care, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Saxony, Germany., Franz AR; Department of Neonatology, University Children's Hospital Tübingen, Tübingen, Baden-Württemberg, Germany.; Center for Pediatric Clinical Studies (CPCS), University Hospital Tübingen, Tübingen, Baden-Württemberg, Germany.

Publikováno v: Archives of disease in childhood. Fetal and neonatal edition [Arch Dis Child Fetal Neonatal Ed] 2023 Dec 15; Vol. 109 (1), pp. 106-111. Date of Electronic Publication: 2023 Dec 15.

Pharmacokinetic/Pharmacodynamic Modelling of Allopurinol, its Active Metabolite Oxypurinol, and Biomarkers Hypoxanthine, Xanthine and Uric Acid in Hypoxic-Ischemic Encephalopathy Neonates.

Autor: Chu WY; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Annink KV; Department of Neonatology, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., Nijstad AL; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands., Maiwald CA; Center for Pediatric Clinical Studies and Department for Neonatology, University Hospital Tuebingen, Tuebingen, Germany., Schroth M; Department of Neonatology and Pediatric Intensive Care, Cnopf Children's Hospital, Nuremberg, Germany., Bakkali LE; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., van Bel F; Department of Neonatology, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., Benders MJNL; Department of Neonatology, University Medical Center Utrecht Brain Center, Utrecht University, Utrecht, The Netherlands., van Weissenbruch MM; Department of Neonatology, Emma Children's Hospital, Amsterdam UMC, Location VUmc, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands., Hagen A; Department of Neonatology and Pediatric Intensive Care, Cnopf Children's Hospital, Nuremberg, Germany., Franz AR; Center for Pediatric Clinical Studies and Department for Neonatology, University Hospital Tuebingen, Tuebingen, Germany., Dorlo TPC; Department of Pharmacy and Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Allegaert K; Department of Development and Regeneration, and Pharmaceutical and Pharmacological Sciences, KU Leuven, Leuven, Belgium.; Department of Clinical Pharmacy, Erasmus MC, Rotterdam, The Netherlands., Huitema ADR; Department of Clinical Pharmacy, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands. a.huitema@nki.nl.; Department of Pharmacy and Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands. a.huitema@nki.nl.; Department of Pharmacology, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands. a.huitema@nki.nl.

Publikováno v: Clinical pharmacokinetics [Clin Pharmacokinet] 2022 Feb; Vol. 61 (2), pp. 321-333. Date of Electronic Publication: 2021 Oct 07.