Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Maite Muñoz-Melero"'
B cell focused transient immune suppression protocol for efficient AAV readministration to the liver
Autor:
Jyoti Rana, Roland W. Herzog, Maite Muñoz-Melero, Kentaro Yamada, Sandeep R.P. Kumar, Anh K. Lam, David M. Markusic, Dongsheng Duan, Cox Terhorst, Barry J. Byrne, Manuela Corti, Moanaro Biswas
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 1, Pp 101216- (2024)
Adeno-associated virus (AAV) vectors are used for correcting multiple genetic disorders. Although the goal is to achieve lifelong correction with a single vector administration, the ability to redose would enable the extension of therapy in cases in
Externí odkaz:
https://doaj.org/article/dbfee83096ee41878357669ddf1b4522
Autor:
Moanaro Biswas, Kaman So, Thais B. Bertolini, Preethi Krishnan, Jyoti Rana, Maite Muñoz-Melero, Farooq Syed, Sandeep R. P. Kumar, Hongyu Gao, Xiaoling Xuei, Cox Terhorst, Henry Daniell, Sha Cao, Roland W. Herzog
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Oral administration of antigen induces regulatory T cells (Treg) that can not only control local immune responses in the small intestine, but also traffic to the central immune system to deliver systemic suppression. Employing murine models of the in
Externí odkaz:
https://doaj.org/article/305eae01744641ecb9a275cdec627bbe
CAR- and TRuC-redirected regulatory T cells differ in capacity to control adaptive immunity to FVIII
Autor:
Jyoti Rana, Sandeep R. P. Kumar, Todd M. Brusko, Rania Saboungi, Moanaro Biswas, Maite Muñoz-Melero, Daniel J. Perry
Publikováno v:
Molecular Therapy. 29:2660-2676
Regulatory T cells (Tregs) control immune responses in autoimmune disease, transplantation, and enable antigen-specific tolerance induction in protein-replacement therapies. Tregs can exert a broad array of suppressive functions through their T cell
Autor:
Miguel Gonzalez-Visiedo, Roland W. Herzog, Maite Munoz-Melero, Sophia A. Blessinger, Joan M. Cook-Mills, Henry Daniell, David M. Markusic
Publikováno v:
Viruses, Vol 16, Iss 7, p 1125 (2024)
Food allergy (FA) is estimated to impact up to 10% of the population and is a growing health concern. FA results from a failure in the mucosal immune system to establish or maintain immunological tolerance to innocuous dietary antigens, IgE productio
Externí odkaz:
https://doaj.org/article/9a57a1000a05483fb8e70f3d617faad2
Autor:
Miguel Gonzalez-Visiedo, Xin Li, Maite Munoz-Melero, Michael D. Kulis, Henry Daniell, David M. Markusic
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 26, Iss , Pp 309-322 (2022)
Immunotherapies for patients with food allergy have shown some success in limiting allergic responses. However, these approaches require lengthy protocols with repeated allergen dosing and patients can relapse following discontinuation of treatment.
Externí odkaz:
https://doaj.org/article/5eb6814f4187470190ad8278d7d9c90c