Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Maite G. Férnandez-Barrena"'
Publikováno v:
Molecular Oncology, Vol 18, Iss 9, Pp 2107-2110 (2024)
Rewiring of cellular metabolism is now fully recognized as a hallmark of cancer. Tumor cells reprogram metabolic pathways to meet the energetic and macromolecular demands to support unrestricted growth and survival under unfavorable conditions. It is
Externí odkaz:
https://doaj.org/article/4357e0c3e3124af3bb2300de6cdfa96b
Autor:
Carla Rojo, María Gárate-Rascón, Miriam Recalde, Ane Álava, María Elizalde, María Azkona, Iratxe Aldabe, Elisabet Guruceaga, Amaya López-Pascual, M Ujue Latasa, Bruno Sangro, Maite G. Fernández-Barrena, Matías A. Ávila, María Arechederra, Carmen Berasain
Publikováno v:
JHEP Reports, Vol 6, Iss 8, Pp 101118- (2024)
Background & Aims: The homeostasis of the cellular transcriptome depends on transcription and splicing mechanisms. Moreover, the fidelity of gene expression, essential to preserve cellular identity and function is secured by different quality control
Externí odkaz:
https://doaj.org/article/839678c118424464b7ef2ce1b0908674
Autor:
Amaya Lopez-Pascual, Marc Cusachs, María Arechederra, Carmen Berasain, Matías A. Ávila, Maite G. Fernández-Barrena
Publikováno v:
Exploration of Digestive Diseases, Vol 1, Iss 2, Pp 80-96 (2022)
Caspases are key factors in the regulation of the apoptotic and/or inflammatory responses, both crucial in the pathogenesis of diverse diseases. Caspase-2 is the most evolutionary conserved albeit functionally poorly defined member of the caspase fam
Externí odkaz:
https://doaj.org/article/d92e9ff5315d42238b0b96d2e9861c93
Autor:
Leticia Colyn, Gloria Alvarez-Sola, M. Ujue Latasa, Iker Uriarte, Jose M. Herranz, Maria Arechederra, George Vlachogiannis, Colin Rae, Antonio Pineda-Lucena, Andrea Casadei-Gardini, Federica Pedica, Luca Aldrighetti, Angeles López-López, Angeles López-Gonzálvez, Coral Barbas, Sergio Ciordia, Sebastiaan M. Van Liempd, Juan M. Falcón-Pérez, Jesus Urman, Bruno Sangro, Silve Vicent, Maria J. Iraburu, Felipe Prosper, Leonard J. Nelson, Jesus M. Banales, Maria Luz Martinez-Chantar, Jose J. G. Marin, Chiara Braconi, Christian Trautwein, Fernando J. Corrales, F. Javier Cubero, Carmen Berasain, Maite G. Fernandez-Barrena, Matias A. Avila
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background Cholangiocarcinoma (CCA) is still a deadly tumour. Histological and molecular aspects of thioacetamide (TAA)-induced intrahepatic CCA (iCCA) in rats mimic those of human iCCA. Carcinogenic changes and therapeutic vulnerabilities i
Externí odkaz:
https://doaj.org/article/278c7dac66c24c988487ac905912005b
Autor:
Maria Rita Braghini, Oriana Lo Re, Ilaria Romito, Maite G. Fernandez-Barrena, Barbara Barbaro, Silvia Pomella, Rossella Rota, Manlio Vinciguerra, Matias A. Avila, Anna Alisi
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-21 (2022)
Abstract Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer, being the sixth most commonly diagnosed cancer and the fourth leading cause of cancer-related death. As other heterogeneous solid tumours, HCC results from a unique sy
Externí odkaz:
https://doaj.org/article/751e8906da5d41f0852a7aad588e4016
Autor:
María Gárate-Rascón, Miriam Recalde, Carla Rojo, Maite G. Fernández-Barrena, Matías A. Ávila, María Arechederra, Carmen Berasain
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13411 (2022)
SLU7 (Splicing factor synergistic lethal with U5 snRNA 7) was first identified as a splicing factor necessary for the correct selection of 3′ splice sites, strongly impacting on the diversity of gene transcripts in a cell. More recent studies have
Externí odkaz:
https://doaj.org/article/baa076ee88a54570b82ca350d497856b
Autor:
Maite G. Fernández-Barrena, María Arechederra, Leticia Colyn, Carmen Berasain, Matias A. Avila
Publikováno v:
JHEP Reports, Vol 2, Iss 6, Pp 100167- (2020)
Summary: Hepatocellular carcinoma (HCC) is a deadly tumour whose causative agents are generally well known, but whose pathogenesis remains poorly understood. Nevertheless, key genetic alterations are emerging from a heterogeneous molecular landscape,
Externí odkaz:
https://doaj.org/article/f2a9405c97b444279b2c7996898e492b
Autor:
Alex Claveria-Cabello, Leticia Colyn, Maria Arechederra, Jesus M. Urman, Carmen Berasain, Matias A. Avila, Maite G. Fernandez-Barrena
Publikováno v:
Cells, Vol 9, Iss 10, p 2321 (2020)
Chronic liver diseases (CLD) represent a worldwide health problem. While CLDs may have diverse etiologies, a common pathogenic denominator is the presence of liver fibrosis. Cirrhosis, the end-stage of CLD, is characterized by extensive fibrosis and
Externí odkaz:
https://doaj.org/article/18999c9f1d0c4f588307a584d85715e6
Autor:
Matteo Canale, Andrea Casadei-Gardini, Paola Ulivi, Maria Arechederra, Carmen Berasain, Pier-Luigi Lollini, Maite G. Fernández-Barrena, Matías A. Avila
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 15, p 5500 (2020)
Gastric cancer (GC) is one of the deadliest malignancies worldwide. Complex disease heterogeneity, late diagnosis, and suboptimal therapies result in the poor prognosis of patients. Besides genetic alterations and environmental factors, it has been d
Externí odkaz:
https://doaj.org/article/80935d64283843258726a4a6040830b3
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 10, p 2507 (2019)
Liver fibrosis is an essential component of chronic liver disease (CLD) and hepatocarcinogenesis. The fibrotic stroma is a consequence of sustained liver damage combined with exacerbated extracellular matrix (ECM) accumulation. In this context, activ
Externí odkaz:
https://doaj.org/article/17d081f97a684b79be61a149318fe405