Fluorescent chitosan-based nanohydrogels and encapsulation of gadolinium MRI contrast agent for magneto-optical imaging

Autor: Juliette Moreau, Maité Callewaert, Volodymyr Malytskyi, Céline Henoumont, Sorina N. Voicu, Miruna S. Stan, Michael Molinari, Cyril Cadiou, Sophie Laurent, Françoise Chuburu

Publikováno v: Carbohydrate Polymer Technologies and Applications, Vol 2, Iss , Pp 100104- (2021)

In the field of medical imaging, multimodal nanoparticles combining complementary imaging modalities can give rise to new forms of imaging techniques that are able to make diagnosis more precise and confident. In this context, resolution and sensitiv

Externí odkaz: https://doaj.org/article/73ca52aacf0f46dfabf9d3fbd7e7ea3a

Synthesis and Characterization of Conjugated Hyaluronic Acids. Application to Stability Studies of Chitosan-Hyaluronic Acid Nanogels Based on Fluorescence Resonance Energy Transfer

Autor: Volodymyr Malytskyi, Juliette Moreau, Maité Callewaert, Céline Henoumont, Cyril Cadiou, Cécile Feuillie, Sophie Laurent, Michael Molinari, Françoise Chuburu

Publikováno v: Gels, Vol 8, Iss 3, p 182 (2022)

Hyaluronic acid (HA) was functionalized with a series of amino synthons (octylamine, polyethylene glycol amine, trifluoropropyl amine, rhodamine). Sodium hyaluronate (HAs) was first converted into its protonated form (HAp) and the reaction was conduc

Externí odkaz: https://doaj.org/article/22fa250717c344f7aa17d15d03ba167c

Biocompatibility of Gd-Loaded Chitosan-Hyaluronic Acid Nanogels as Contrast Agents for Magnetic Resonance Cancer Imaging

Autor: Cecilia Virginia Gheran, Guillaume Rigaux, Maité Callewaert, Alexandre Berquand, Michael Molinari, Françoise Chuburu, Sorina Nicoleta Voicu, Anca Dinischiotu

Publikováno v: Nanomaterials, Vol 8, Iss 4, p 201 (2018)

Although the research on nanogels incorporating Gd chelates for theranostic applications has grown exponentially in recent years, knowledge about their biocompatibility is limited. We compared the biocompatibility of Gd-loaded hyaluronic acid-chitosa

Externí odkaz: https://doaj.org/article/74985fc79c614f149035fde50e760e4b

Pyclen-based Gd complex with ionisable side-chain as a contrastophore for the design of hypersensitive MRI nanoprobes: Synthesis and relaxation studies

Autor: Françoise Chuburu, Sophie Laurent, Maité Callewaert, Céline Henoumont, Cyril Cadiou, Michael Molinari, Fabienne Dioury, Marc Port, Christophe Portefaix

Publikováno v: Results in Chemistry
Results in Chemistry, Elsevier, 2021, 3, pp.100237. ⟨10.1016/j.rechem.2021.100237⟩
Results in Chemistry, Vol 3, Iss, Pp 100237-(2021)

A straightforward method for synthesizing at the multigram scale a low molecular weight PCTA-based gadolinium complex bearing an ionizable oxyacetic chain on the pyridine unit was described, together with its encapsulation within a nanohydrogel matri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd6c033096832e11a1a034af851b6d0
https://hal.archives-ouvertes.fr/hal-03435946/document

Fluorescent Chitosan Nanogels Developed for Targeting Endothelial Cells of Axillary Lymph Nodes

Autor: Hildegard Herman, Sorina Nicoleta Voicu, Anca Dinischiotu, Juliette Moreau, Cyril Cadiou, Françoise Chuburu, Ionela Cristina Nica, Maité Callewaert, Anca Hermenean, Miruna-Silvia Stan

Publikováno v: The 2nd International Online-Conference on Nanomaterials.

Nanogels are a novel class of three-dimensional cross-linked polymers able to retain high amounts of water in their network structure, with large potential applications in nanomedicine. In our study, the polymer matrix selected was chitosan, as this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4aa4834473dc7c5c679051b6e7d1d6a8
https://doi.org/10.3390/iocn2020-07847